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Unbound Medicine.
(uterus-didelphys)
422 results
  • Mayer-Rokitansky-Küster-Hauser syndrome with rare findings of inferior crossed-fused renal ectopia and Gartner's duct cyst: a video case report. [Journal Article]
    Fertil Steril. 2020 Oct 14 [Online ahead of print]Liang G, Xia W, … Jiang H
  • CONCLUSIONS: The distal Wolffian ducts in the female are absorbed but may persist as vestigial remnants (Gartner's duct cysts). A few cases of the combined urogenital-Wolffian anomalies are reported; most of them are associated with the anomalies of müllerian duct fusion, such as Herlyn-Werner-Wunderlich syndrome (uterus didelphys, obstructed hemivagina, and mesonephric duct anomalies). The embryogenesis of the combined anomalies is not completely understood. With comprehensive preoperative assessments, laparoscopic surgery could be a safe and effective treatment to these cases.
  • Herlyn-Werner-Wunderlich Syndrome: Comparison of Two Cases. [Case Reports]
    Int J Environ Res Public Health. 2020 Sep 30; 17(19)Kozłowski M, Nowak K, … Cymbaluk-Płoska A
  • CONCLUSIONS: Lower abdominal pain accompanying hematocolpos suggested Herlyn-Werner-Wunderlich Syndrome (HWWS) as the cause of symptoms. 3D transvaginal ultrasound enabled the determination of a congenital uterine defect with high probability, although inconclusive cases required confirmation by laparoscopy. Incision of the blocked vagina and drainage of hematocolpos were the key components of treatment. The treatment of HWWS is a multi-step process.
  • Longitudinal vaginal septum: a proposed classification and surgical management. [Journal Article]
    Fertil Steril. 2020 Oct; 114(4):899-901.Ludwin A, Lindheim SR, … Ludwin I
  • CONCLUSIONS: A new classification of longitudinal vaginal septum allows better characterization compared with the currently available classification systems. Different surgical modalities are discussed with their respective advantages and disadvantages. Vaginoscopic incision using resectoscope is a reasonable alternative for women with an intact hymen and vaginal stenosis. The impact of vaginal septum resection on obstetric, reproductive, and sexual outcomes should be assessed in randomized controlled trials and large well-designed studies.
  • Coexistence of urogenital malformations in a female fetus with de novo 15q24 microdeletion and a literature review. [Journal Article]
    Mol Genet Genomic Med. 2020 07; 8(7):e1265.Liu Y, Mapow B
  • CONCLUSIONS: We report the first case of coexistence of urogenital abnormalities, including left kidney agenesis and uterus didelphys, with 15q24 microdeletion syndrome, which is also associated with midline defects secondary to abnormal development. Since 15q24 microdeletion syndrome is a relatively new entity, fully characterizing its variation and severity requires additional examination of the genetics, molecular profile and structural and functional abnormalities in affected patients. Due to the limited data in the literature, statistical analysis of abnormalities in each organ system is not possible. However, we can predict that novel genetic pathways involving cell migration, adhesion, apoptosis, and embryo development might be discovered with the advanced study of 15q24 microdeletion syndrome.
  • Pregnancy and Childbirth in Uterus Didelphys: A Report of Three Cases. [Case Reports]
    Medicina (Kaunas). 2020 Apr 23; 56(4)Slavchev S, Kostov S, Yordanov A
  • Uterus didelphys is a rare form of congenital anomaly of the Müllerian ducts. The clinical significance of this anomaly of the female reproductive tract is associated with various reproductive issues: increased risk of preterm birth before 37 weeks' gestation, abnormal fetal presentation, delivery by caesarean section, intrauterine fetal growth restriction, low birth weight less than 2500 g, and …
  • An interesting case of Herlyn-Werner-Wunderlich syndrome. [Case Reports]
    Ci Ji Yi Xue Za Zhi. 2020 Apr-Jun; 32(2):216-218.Tigga MP
  • Herlyn-Werner-Wunderlich syndrome (HWWS) is a rare congenital anomaly characterized by uterus didelphys with blind hemivagina and ipsilateral renal agenesis. Usually, such patients present with dysmenorrhea shortly after menarche, increasing pelvic pain and a palpable mass due to the obstructed hemivagina. Interestingly in the present case, the patient had her menarche seven years ago, but dysmen…
  • Resection of Longitudinal Vaginal Septum Using a Surgical Stapler. [Case Reports]
    J Pediatr Adolesc Gynecol. 2020 Aug; 33(4):435-437.Chu K, James D, … Velcek F
  • CONCLUSIONS: We introduce a safe and effective technique for resecting a longitudinal vaginal septum using stapler technology. This technique eliminates the potential risk of thermal injury to nearby structures from currently described methods.
  • Diagnosis and treatment of müllerian malformations. [Review]
    Taiwan J Obstet Gynecol. 2020 Mar; 59(2):183-188.Passos IMPE, Britto RL
  • Anomalies in the müllerian ducts are congenital alterations with more prevalence than it is imagined, varying from 0.5 to 6.7% in the general population and up to 16.7% in women with recurrent miscarriage. The main findings are primary amenorrhea, dysmenorrhea, pelvic pain, endometriosis, sexual difficulties and low self-esteem. The major impact on the quality of life in women stricken by these p…
  • Extracranial midline defects in a patient with craniofrontonasal syndrome with a novel EFNB1 mutation. [Case Reports]
    . 2020 05; 182(5):1223-1229.Acosta-Fernández E, Zenteno JC, … Corona-Rivera JR
  • We report a female patient with craniofrontonasal syndrome (CFNS) who in addition showed other cranial and extracranial midline defects including partial corpus callosum agenesis, ocular melanocytosis, pigmentary glaucoma, duplex collecting system, uterus didelphys, and septate vagina. She was found to have a novel pathogenic variant in exon 5 of EFNB1, c.646G>T (p.Glu216*) predicted to cause pre…
  • Ovarian dysgerminoma with Müllerian anomaly: a case report. [Case Reports]
    Obstet Gynecol Sci. 2020 Jan; 63(1):98-101.Kim HN, Byun JM, … Sung MS
  • Müllerian anomalies are rare deformities in women, and only a few cases concerning gynecologic malignancies arising in patients with congenital uterine malformations have been reported. Herein, we present the case of a 34-year-old woman with dysgerminoma with a Müllerian anomaly (uterus didelphys). She had secondary amenorrhea, and an ovarian mass and uterus didelphys were discovered during exami…
  • Successful external cephalic version in a patient with uterus didelphys and fetal malpresentation. [Case Reports]
    BMJ Case Rep. 2019 Nov 19; 12(11)Mirzai S, Wolf SB, … Rifai AO
  • Müllerian anomalies are congenital malformations of the female reproductive organs that occur when the müllerian ducts develop abnormally. Different types of müllerian anomalies have different pregnancy outcomes. Breech presentation is a common occurrence in pregnant women with uterus didelphys, and caesarean section is the traditional mode of delivery under such circumstances. Here, we present t…
  • Herlyn-Werner-Wunderlich syndrome: Diagnosis and treatment of an atypical case and review of literature. [Journal Article]
    Int J Surg Case Rep. 2019; 63:129-134.Girardi Fachin C, Aleixes Sampaio Rocha JL, … Dos Santos Dias AIB
  • CONCLUSIONS: With normal external genitalia, HWWS is usually asymptomatic until menarche when patients present with worsening abdominal pain during menses and a palpable pelvic or abdominal mass. Untreated, HWWS may lead to a number of complications including endometriosis, infertility, and spontaneous abortion.Greater awareness of HWWS will lead to earlier detection and is the key to alleviating patient suffering and avoiding potentially severe complications.
  • An Unusual Cause of Recurrent Urinary Retention in an Adolescent Female. [Case Reports]
    Cureus. 2019 Jul 15; 11(7):e5136.Gajendran I, Uzamere O, … Pierre L
  • Herlyn-Werner-Wunderlich syndrome (HWWS) is a rare, combined Mullerian and Mesonephric duct anomaly characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. We present the case of an otherwise healthy 16-year-old female with acute urinary retention secondary to HWWS. The diagnosis was established with abdominal ultrasound and Magnetic Resonance Imaging…
  • How many challenges we may encounter in anterior megalophthalmos with white cataract: a case report. [Case Reports]
    BMC Ophthalmol. 2019 May 30; 19(1):122.Miao A, Zhang K, … Zhu X
  • CONCLUSIONS: We presented the challenges and the original findings from a case of congenital anterior megalophthalmos with white cataract who underwent phacoemulsification and IOL implantation. This is the first report describing the comparison of the different IOL power calculation formulas in anterior megalophthalmos. Compared to the SRK/T and the Holladay II formulas, the Haigis formula could be a more accurate choice for the IOL calculation in anterior megalophthalmos according to our case. Moreover, the deliberate selection of IOLs is essential for IOL stability in these patients.
  • Herlyn-Werner-Wunderlich syndrome - a rare genitourinary anomaly in females: a series of four cases. [Case Reports]
    Pol J Radiol. 2018; 83:e306-e310.Ilyas M, Khan I, Saldanha CL
  • We present case series of four patients with an important syndrome known as Herlyn-Werner-Wunderlich syndrome. Herlyn-Werner-Wunderlich syndrome is a rare congenital anomaly characterised by uterus didelphys with blind hemivagina and ipsilateral renal agenesis. It usually presents after menarche with progressive pelvic pain during menses secondary to haematocolpos. Awareness is necessary to diagn…
  • Herlyn-Werner-Wunderlich Syndrome: Report of a Prenatally Recognised Case and Review of the Literature. [Case Reports]
    Urology. 2019 Mar; 125:205-209.Tuna T, Estevão-Costa J, … Fragoso AC
  • Herlyn-Werner-Wunderlich syndrome, defined by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis, is a rare Mullerian malformation, usually diagnosed after menarche, when symptoms related to hematocolpos arise. Rarely, this malformation is diagnosed in the neonatal period, normally following prenatal diagnosis of renal agenesis. Herein, a case recognized on prenat…
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