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4,309 results
  • Growth and cellular patterning during fetal human inner ear development studied by a correlative imaging approach. [Journal Article]
  • BDBMC Dev Biol 2019 May 20; 19(1):11
  • Johnson Chacko L, Wertjanz D, … Handschuh S
  • CONCLUSIONS: We present structural information on human inner ear development across multiple levels of biological organization, including gross-morphology of the inner ear, cellular and subcellular details of hearing and vestibular organs, as well as ultrastructural details in the developing sensory epithelia. This enabled the gathering of detailed information regarding morphometric changes as well in realizing the complex developmental patterns of the human inner ear. We were able to quantify the volumetric and linear aspects of selected gestational inner ear specimens enabling a better understanding of the cellular changes across the fetal gestational timeline. Moreover, these data could serve as a reference for better understanding disorders that arise during inner ear development.
  • Otopetrin-2 Immunolocalization in the Human Macula Utricle. [Journal Article]
  • AOAnn Otol Rhinol Laryngol 2019; 128(6_suppl):96S-102S
  • Lopez PhD IA, Ishiyama Md G, … Ishiyama Md A
  • CONCLUSIONS: Otopetrin-2 was localized in supporting cells in a similar fashion that otopetrin-1 previously reported in the mouse macula utricle. The differential expression of otopetrin-2 in the supporting cells of the human macula utricle suggest an important role in the vestibular sensory periphery homeostasis and otolith maintenance.
  • Vestibular function in panic disorder patients: a vestibular-evoked myogenic potentials and video head impulse test study. [Journal Article]
  • EAEur Arch Otorhinolaryngol 2019; 276(6):1607-1616
  • Angov G, Mihaylova-Angelova E, … Stambolieva K
  • CONCLUSIONS: The VEMPs and vHIT tests demonstrated that there is no evidence of hypofunction of the semicircular canals in the high-frequency spectrum of VOR functioning. Nor are there any indications of impairment of the otolith system in patients with PD, regardless of their subjective vestibular sensations. The findings of the current study confirm the proposed link between anxiety, panic symptoms and postural instability in PD patients.
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