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Unbound Medicine.
(uvula of cerebellum)
4,550 results
  • A Third Somatomotor Representation in the Human Cerebellum. [Journal Article]
    J Neurophysiol. 2022 Sep 21 [Online ahead of print]Saadon-Grosman N, Angeli PA, … Buckner RL
  • Seminal neurophysiological studies in the 1940s discovered two somatomotor maps in the cerebellum - an inverted anterior lobe map and an upright posterior lobe map. Both maps have been confirmed in the human using non-invasive neuroimaging with additional hints of a third map within and near to the cerebellar vermis. Here we sought direct evidence for the third somatomotor map by using intensive,…
  • Epidermoid cyst of the cerebellar vermis: Case report of a rare medial topography. [Case Reports]
    Radiol Case Rep. 2022 Nov; 17(11):4248-4251.Diop AD, Dia AM, … Ba S
  • Intracranial epidermoid cysts are very rare benign tumors representing less than 2% of intracranial tumors. They are located preferentially in the cerebellopontine angles, parasellar, and temporal regions. We report here the case of an epidermoid cyst of very uncommon medial location in the cerebellar vermis, in a 61-year-old female patient complicated with tumor protrusion into the foramen magnu…
  • The Yin and Yang of Operating on a Posterior Fossa Meningioma: The Schmahmann Syndrome. [Case Reports]
    Neurol India. 2022 Jul-Aug; 70(4):1661-1664.Ruparelia J, Gosal JS, … Bhatia PK
  • The cerebellum is classically linked with control of motor function, such as coordination, balance, and regulation of movement. There is an increasing awareness, now, of the non-motor functions of the cerebellum, and the occurrence of behavioral anomalies with cerebellar disorders. We present the first report of Schmahmann syndrome (cerebellar cognitive affective syndrome [CCAS]) occurring second…
  • Paraneoplastic Cerebellar Degeneration With P/Q-VGCC vs Yo Autoantibodies. [Journal Article]
    Neurol Neuroimmunol Neuroinflamm. 2022 Jul; 9(4)Winklehner M, Bauer J, … Höftberger R
  • CONCLUSIONS: Anti-Yo-PCD showed characteristic features of a T cell-mediated pathology, whereas this was not observed in 1 case of anti-P/Q-VGCC-PCD. Our findings support a pathogenic role of anti-P/Q-VGCC autoantibodies in causing neuronal dysfunction, probably due to altered synaptic transmission resulting in calcium dysregulation and subsequent PC death. Because disease progression may lead to irreversible PC loss, anti-P/Q-VGCC-PCD patients could benefit from early oncologic and immunologic therapies.
  • Multiple ciliary localization signals control INPP5E ciliary targeting. [Journal Article]
    Elife. 2022 Sep 05; 11Cilleros-Rodriguez D, Martin-Morales R, … Garcia-Gonzalo FR
  • Primary cilia are sensory membrane protrusions whose dysfunction causes ciliopathies. INPP5E is a ciliary phosphoinositide phosphatase mutated in ciliopathies like Joubert syndrome. INPP5E regulates numerous ciliary functions, but how it accumulates in cilia remains poorly understood. Herein, we show INPP5E ciliary targeting requires its folded catalytic domain and is controlled by four conserved…
  • A Rare Case of Pontocerebellar Hypoplasia Type 1B With Literature Review. [Case Reports]
    Cureus. 2022 Jul; 14(7):e27098.Spyridakis AC, Cao Y, Litra F
  • A full-term female newborn was transferred to our neonatal intensive care unit (NICU) on day two of life for hypotonia. Physical examination was significant for overriding sutures, displaced small anterior fontanelle, axial hypotonia, extremity hypertonia, and slow deep tendon reflexes. She was also noted to have stridor with crying but had unlabored breathing without oxygen requirements and a no…
  • Explicit and Implicit Emotion Processing in the Cerebellum: A Meta-analysis and Systematic Review. [Journal Article]
    Cerebellum. 2022 Aug 23 [Online ahead of print]Pierce JE, Thomasson M, … Péron J
  • The cerebellum's role in affective processing is increasingly recognized in the literature, but remains poorly understood, despite abundant clinical evidence for affective disruptions following cerebellar damage. To improve the characterization of emotion processing and investigate how attention allocation impacts this processing, we conducted a meta-analysis on task activation foci using GingerA…
  • Insular functional connectivity in migraine with aura. [Journal Article]
    J Headache Pain. 2022 Aug 19; 23(1):106.Gollion C, Lerebours F, … Péran P
  • CONCLUSIONS: The anterior insula and superior cerebellum, including vermis VI, are components of the central Autonomic Nervous System (ANS) network. As these regions are involved in the control of cardiovascular parasympathetic tone, we hypothesize that this connectivity may reflect the cardiovascular features of MA.The anterior dorsal insula is connected with vermis VI in MA patients in the resting state. This connectivity may reflect the cardiovascular features of MA.
  • Cerebello-Thalamo-Cortical Network Dynamics in the Harmaline Rodent Model of Essential Tremor. [Journal Article]
    Front Syst Neurosci. 2022; 16:899446.Woodward K, Apps R, … Cerminara NL
  • Essential Tremor (ET) is a common movement disorder, characterised by a posture or movement-related tremor of the upper limbs. Abnormalities within cerebellar circuits are thought to underlie the pathogenesis of ET, resulting in aberrant synchronous oscillatory activity within the thalamo-cortical network leading to tremors. Harmaline produces pathological oscillations within the cerebellum, and …
  • Atezolizumab-associated encephalitis in metastatic breast cancer: A case report. [Journal Article]
    Oncol Lett. 2022 Sep; 24(3):324.Chen G, Zhang C, … Zhao Y
  • Immune checkpoint inhibitors have been critical in the treatment of advanced malignancies in recent years. Encephalitis caused by atezolizumab is an uncommon immune-related adverse event. The case of a 65-year-old female diagnosed with encephalitis closely associated with atezolizumab medication for metastatic advanced breast cancer is presented in the current study. Following a fourth atezolizum…
  • Joubert-Plus syndrome with an atretic cephalocele: a case report. [Case Reports]
    Radiol Case Rep. 2022 Oct; 17(10):3630-3634.Al-Smair A, Younes S, … Jaber O
  • Joubert syndrome is a rare heterogeneous disease affecting the cerebellum. It usually presents with hypotonia, abnormal breathing pattern, with distinctive cerebellar and brain stem malformation called the molar tooth sign. It may present with different organ involvement or with other neurological alterations such as Dandy-Walker syndrome. Joubert syndrome with dandy walker syndrome is called Jou…
  • Cerebellum and Neurorehabilitation in Emotion with a Focus on Neuromodulation. [Journal Article]
    Adv Exp Med Biol. 2022; 1378:285-299.van Dun K, Manto M, Meesen R
  • More and more research has focused on the role of the cerebellum in emotions and social cognition. Structural cerebellar and cerebello-cerebral connectivity abnormalities have been identified in several prevalent neuropsychiatric conditions, which have in some cases even been linked to the severity of the emotional disorder.Non-invasive brain stimulation (NIBS) techniques are currently used to mo…
  • The Neurophysiology of the Cerebellum in Emotion. [Journal Article]
    Adv Exp Med Biol. 2022; 1378:87-108.Adamaszek M, Kirkby KC
  • Neuroscientific investigation of the detailed neurophysiology of emotion processing is a rapidly progressing field, which has opened discussion on key findings regarding the timing characteristics of the neuronal networks involved. Study designs incorporating quantitative electroencephalography (EEG) and event-related potentials (ERP) have mapped neuronal representations at various stages of emot…
  • Cerebellum and Emotion Memory. [Journal Article]
    Adv Exp Med Biol. 2022; 1378:53-73.Mark M, Pakusch J, … Timmann D
  • Fear is an important emotion for survival, and the cerebellum has been found to contribute not only to innate affective and defensive behavior, but also to learned fear responses. Acquisition and retention of fear conditioned bradycardia and freezing have been shown to depend on the integrity of the cerebellar vermis in rodents. There is a considerable number of brain imaging studies, which obser…
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