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(vaccine therapy)
116,924 results
  • Current prevention and potential treatment options for dengue infection. [Journal Article]
    J Pharm Pharm Sci 2019; 22(1):440-456Jasamai M, Yap WB, … Jaleel A
  • Currently, treatments for dengue infection are only symptomatic as no antiviral agents nor vaccines are available to combat this virus. Despite challenges faced by researchers, many efforts are ongoing to reduce cases of dengue infection either by targeting the vector or the virus. Vector population is monitored and reduced by using mechanical, chemical and biological controls. Chemical control i…
  • Hepatitis B infection in the general population of China: a systematic review and meta-analysis. [Journal Article]
    BMC Infect Dis 2019; 19(1):811Wang H, Men P, … Wu J
  • CONCLUSIONS: The prevalence of HBV infection in the general population of China was classified as higher intermediate prevalence (5-7.99%), of which more than 90% of the HBV infection population included adults older than 20 years. The blocking of mother-to-infant hepatitis B transmission and plans involving timely birth dose of hepatitis B vaccine within 24 h should be implemented. Additionally, improving the quality of life and survival rate of the infected population through antiviral therapy and high-risk adult vaccination will be the priority of our future work. Moreover, various control measures should be implemented in different provinces across China.
  • The Landscape of Early Clinical Gene Therapies outside of Oncology. [Review]
    Mol Ther 2019Rittié L, Athanasopoulos T, … Clay TM
  • The field of cell and gene therapy (GT) is expanding rapidly and there is undoubtedly a wave of enthusiasm and anticipation for what these treatments could achieve next. Here we assessed the worldwide landscape of GT assets currently in early clinical development (clinical trial phase 1/2 or about to enter clinical trial). We included all gene therapies, i.e., strategies that modify an individual…
  • How plausible is an Alzheimer's disease vaccine? [Journal Article]
    Expert Opin Drug Discov 2019; :1-6Cacabelos R
  • Introduction: Alzheimer's disease (AD) vaccination is one of the last therapeutic options after two decades of stagnation in terms of drug development. About 140 (85%) immunization procedures against Aβ deposition and 25 (15%) against Tau have been reported, but no Food and Drug Administration approval of any AD vaccine has been achieved. This might be attributed to deficient pathogenic targets, …
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