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(vacuole)
33,501 results
  • Increased Tattoo Fading in a Single Laser Tattoo Removal Session Enabled by a Rapid Acoustic Pulse Device: A Prospective Clinical Trial. [Case Reports]
    Lasers Surg Med 2019Kaminer MS, Capelli CC, … Robertson DW
  • CONCLUSIONS: The RAP device, applied as an accessory to the 1064 nm Nd:YAG QS laser, safely enables multiple QS laser treatments in a single office laser tattoo removal session by clearing the whitening caused by the previous QS laser pass. Enabling multiple QS laser passes results in a statistically significant increase in tattoo fading in a single office laser tattoo removal session compared to the clinical standard single-pass QS laser tattoo removal session. © 2019 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.
  • The Atlastin ER-shaping proteins facilitate Zika virus replication. [Journal Article]
    J Virol 2019Monel B, Rajah MM, … Schwartz O
  • The Endoplasmic Reticulum (ER) is the site for Zika virus (ZIKV) replication and is central to the cytopathic effects observed in infected cells. ZIKV induces the formation of ER-derived large cytoplasmic vacuoles followed by "implosive" cell death. Little is known about the nature of the ER factors that regulate flavivirus replication. Atlastins (ATL1/2/3) are dynamin-related GTPases that contro…
  • How bacteria can block xenophagy: an insight from Salmonella. [Journal Article]
    Autophagy 2019; :1-2Wen X, Klionsky DJ
  • Xenophagy, a unique type of selective macroautophagy/autophagy, targets invading pathogens as part of the host immune response. In order to survive within the host, bacteria have established various self-defense mechanisms. In a recent paper from Feng Shao's lab, the Salmonella effector protein SopF has been demonstrated to block xenophagy by interrupting the vacuolar type H+-translocating (v-) A…
  • The huntingtin inclusion is a dynamic phase-separated compartment. [Journal Article]
    Life Sci Alliance 2019; 2(5)Aktar F, Burudpakdee C, … Emtage L
  • Inclusions of disordered protein are a characteristic feature of most neurodegenerative diseases, including Huntington's disease. Huntington's disease is caused by expansion of a polyglutamine tract in the huntingtin protein; mutant huntingtin protein (mHtt) is unstable and accumulates in large intracellular inclusions both in affected individuals and when expressed in eukaryotic cells. Using mHt…
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