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22,338 results
  • Conceptualization of a Parasympathetic Endocrine System. [Journal Article]
    Front Neurosci 2019; 13:1008Gorky J, Schwaber J
  • We here propose a parasympathetic endocrine system (PES) comprised of circulating peptides released from secretory cells in the gut, significantly modulated by vagal projections from the dorsal motor nucleus of the vagus (DMV). While most of these gut peptides mediate well-described satiety and digestive effects that increase parasympathetic control of digestion (Lee et al., 1994; Gutzwiller et a…
  • Mechanisms contributing to the genesis of hypoglossal preinspiratory discharge. [Journal Article]
    J Integr Neurosci 2019; 18(3):313-325Ghali MGZ
  • Preinspiratory discharge manifests in the neuronal recordings of the pre-Bötzinger complex, parafacial respiratory group, retrotrapezoid nucleus, and Kölliker-Fuse nucleus, as well as the efferent neural discharge of respiratory-related nerves innervating upper airway musculature. This neural component of triphasic eupnea contemporaneously contributes to the genesis of native and originate respir…
  • Hypertonic Saline Stimulates Vagal Afferents that Respond to Lung Deflation. [Journal Article]
    Am J Physiol Regul Integr Comp Physiol 2019Guardiola J, Saad M, Yu J
  • In our present studies, we seek to determine whether increased osmolarity stimulates deflation-activated receptors (DARs). In anesthetized, open-chest and mechanically ventilated rabbits, we recorded single unit activities from typical slowly adapting receptors (SARs, responding only to lung inflation) and DAR-containing SARs (DAR-SARs, responding to both lung inflation and deflation) and identif…
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