- The aortic root hexagon as an aide memoire to the important surgical landmarks. [Journal Article]Clin Anat 2020CA
- CONCLUSIONS: The aortic root hexagon is made by two triangles superimposed on each other, these are the commissural and nadir triangle respectively. We have found this concept to be a quick way to learn and remember the key anatomical relationships of the aortic root. This article is protected by copyright. All rights reserved.
- Paracentesis as valve re-bubbling technique for Descemet's membrane endothelial keratoplasty (DMEK) graft detachment. [Journal Article]Int Ophthalmol 2020IO
- CONCLUSIONS: Slit-lamp re-bubbling is a practical and safe alternative to taking patients back to the operating room. Using a new paracentesis for valve action control over air injection with a blunt cannula adds better control and may help to reduce complications.
- Early cost-utility analysis of tissue-engineered heart valves compared to bioprostheses in the aortic position in elderly patients. [Journal Article]Eur J Health Econ 2020EJ
- CONCLUSIONS: Despite the relatively short life expectancy of elderly patients undergoing SAVR/TAVI, hypothetical TEHV are predicted to be cost-effective compared to bioprostheses, commercially viable and result in national cost savings when biomedical engineers succeed in realising improved durability and/or infection resistance of TEHV.
- Induction of aortic valve calcification by celecoxib and its COX-2 independent derivatives is glucocorticoid-dependent. [Journal Article]Cardiovasc Pathol 2019; 46:107194CP
- CONCLUSIONS: Here we identify glucocorticoids as a possible source of the increased valvular calcification risk associated with celecoxib and its cyclooxygenase-2 independent derivatives. In the absence of glucocorticoids, these inhibitors effectively reduce calcification. Furthermore, the offtarget effects are not due to the drug's intrinsic properties as dual cyclooxygenase-2 and cadherin-11 inhibitors. These findings inform future design and development of celecoxib derivatives for potential clinical therapy.
- Transcatheter closure of left ventricular pseudoaneurysm after mitral valve replacement. [Case Reports]Ann Thorac Surg 2020AT
- Left ventricular pseudoaneurysm (LVPA) is a rare but lethal complication of mitral valve replacement (MVR) or myocardial infarction. Early correction is necessary for patients with extensive and expanding LVPA. We report a transcatheter closure of LVPA after MVR. A 63-year-old woman presented with an LVPA two months after MVR. The repeated computed tomographic scan and transthoracic echocardiogra…
Left ventricular pseudoaneurysm (LVPA) is a rare but lethal complication of mitral valve replacement (MVR) or myocardial infarction. Early correction is necessary for patients with extensive and expanding LVPA. We report a transcatheter closure of LVPA after MVR. A 63-year-old woman presented with an LVPA two months after MVR. The repeated computed tomographic scan and transthoracic echocardiography showed enhancement of pseudoaneurysm. The LVPA was successfully closed with Amplatzer Vascular Plug by transcatheter approach.
- Misclassification of Mitral Valve Disease and Rate of Surgical Repair in the STS Database (Commentary). [Journal Article]Ann Thorac Surg 2020AT
- Transcatheter closure of a perimembranous ventricular septal defect with Nit-Occlud Lê VSD Coil: A French multicentre study. [Journal Article]Arch Cardiovasc Dis 2020AC
- CONCLUSIONS: pmVSD closure with the Nit-Occlud Lê VSD Coil is feasible in older children and adults. However, residual shunting (leading to haemolysis) is a dreaded complication that should not be tolerated. pmVSD closure with the Nit-Occlud Lê VSD as a therapeutic strategy remains controversial and is limited to selected patients.
- Management of prosthetic valve thrombosis complicated by ischemic stroke in pregnancy. [Letter]Rev Port Cardiol 2020RP
- Acute coronary artery obstruction following surgical repair of congenital heart disease. [Journal Article]J Thorac Cardiovasc Surg 2019JT
- CONCLUSIONS: Time from clinically relevant postoperative sentinel event to diagnosis of coronary artery obstruction by angiography was associated with transplant-listing-free survival. Clinicians should maintain a high index of suspicion for coronary obstruction and consider early catheterization and coronary angiography for patients in whom post-operative coronary compromise is suspected.
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- Daytime variation does not impact outcome of cardiac surgery: Results from a diverse, multi-institutional cardiac surgery network. [Journal Article]J Thorac Cardiovasc Surg 2019JT
- CONCLUSIONS: There were no differences in operative mortality nor in major morbidity between well-matched AM and PM patients undergoing either CABG or AVR.