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183,509 results
  • Survival After Norwood Procedure in High Risk Patients. [Journal Article]
    Ann Thorac Surg 2019Tanem J, Rudd N, … Hill GD
  • CONCLUSIONS: Outcomes following the Norwood procedure have improved for standard risk patients. Those with pre-operative risk factors account for the majority of early mortality following the Norwood procedure. This high risk status does not resolve after Glenn, as longer term survival continues to diverge from the standard risk group.
  • Patients' selection for transcatheter tricuspid valve interventions: Who will benefit? [Review]
    Prog Cardiovasc Dis 2019Harb SC, Kapadia SR
  • Tricuspid regurgitation (TR) is a common valvular pathology and is associated with significant morbidity and mortality. However, there is no currently defined optimal management strategy: medical therapy is limited to diuretics, and tricuspid valve surgery is rarely performed and associated with high risks. This has led to the emergence of numerous transcatheter therapies that are showing promisi…
  • From embryogenesis to adulthood: Critical role for GATA factors in heart development and function. [Review]
    IUBMB Life 2019Whitcomb J, Gharibeh L, Nemer M
  • Cardiac development is governed by a complex network of transcription factors (TFs) that regulate cell fates in a spatiotemporal manner. Among these, the GATA family of zinc finger TFs plays prominent roles in regulating the development of the myocardium, endocardium, and outflow tract. This family comprises six members three of which, GATA4, 5, and 6, are predominantly expressed in cardiac cells…
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