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18,515 results
  • Pregabalin-associated stuttering and frequent blepharospasm: case report and review. [Journal Article]
    Daru. 2020 Jul 06 [Online ahead of print]Ge L, Li A, … Li W
  • Herpes zoster is an acute, painful, herpes skin disease caused by varicella-zoster virus, which may cause viral meningitis. Pregabalin has been shown to be efficacious in the treatment of pain in patients with herpes zoster. However, it has the side effects of neurotoxicity. We describe a 68-year-old female patient with herpes zoster, and she was treated with pregabalin. The patient presented wit…
  • A previously treated severe haemophilia A patient developed high-titre inhibitor after vaccinations. [Journal Article]
    Int J Immunopathol Pharmacol. 2020 Jan-Dec; 34:2058738420934618.Li Z, Chen Z, … Wu R
  • The factor VIII (FVIII)-neutralizing antibody (inhibitor) seen in 25%-30% of patients with severe haemophilia A (SHA). Vaccination is a non-genetic risk factor of inhibitor development as 'danger signal' which may provide a pro-inflammatory microenvironment to increase FVIII immunogenicity. We reported a previously treated SHA patient postponed the first vaccination to 15-month age received dipht…
  • Meningoradiculitis due to varicella zoster virus reactivation in a patient treated with ixekizumab. [Case Reports]
    Ann Dermatol Venereol. 2020 Jun 30 [Online ahead of print]Dubois M, Morel G, … Vermersch-Langlin A
  • CONCLUSIONS: This case raises the question of the risk of viral reactivation during treatment with an IL-17 inhibitor and with biologics in general. Neurological and vascular complications of VZV may occur without skin lesions and their occurrence during ixekizumab therapy must be investigated by PCR testing of CSF for VZV DNA.
  • Coronavirus (COVID-19) Infection-Induced Chilblains: A Brisk Perieccrine Inflammatory Response. [Journal Article]
    Am J Dermatopathol. 2020 Jun 30 [Online ahead of print]Wargo JJ, Weir NM, Shamma HN
  • The varying cutaneous and pathological manifestations of coronavirus 2 (SARS-CoV-2 or COVID-19) may have prognostic implications. Acral ischemic findings present with a hypercoagulable state in critically ill COVID-19 patients. Pathologically confirmed varicella-like exanthem and perniosis COVID-19 cases have correlated with paucisymptomatic and asymptomatic patients in previous reports. We prese…
  • No evidence of SARS-Cov-2 infection by PCR or serology in children with pseudochilblain. [Letter]
    Br J Dermatol. 2020 Jul 01 [Online ahead of print]Caselli D, Chironna M, … Aricò M
  • Despite its aggressive clinical course, leading to 6.4% fatality rate as of May 25, 2020 (, COVID-19 turned out to be only marginally aggressive in children. In a report from Lombardy, 18/88 COVID-19 hospitalized adults (20%) had developed cutaneous manifestations: erythematous rash, widespread urticarial, and chickenpox-like ves…
  • "Vesicular eruption in COVID-19 - to exclude varicella": reply from the authors. [Letter]
    Br J Dermatol. 2020 Jul 01 [Online ahead of print]Català A, Galván Casas C, … García-Doval I
  • We and agree with Drs Lim and Tey on the need to exclude varicella in vesicular eruptions in patients with COVID-19, as this diagnosis has important implications. Once that it is established that some patients with COVID-19 can have a vesicular eruption, there is a need to further characterize this group of patients. The link of some of these lesions with herpesvirus infections is very likely. On…
  • Effects of Intravenous Immunoglobulin and Acyclovir in Preventing Neonatal Varicella. [Case Reports]
    Case Rep Infect Dis. 2020; 2020:2709389.Piyanonpong W
  • Neonatal varicella mostly results from maternal varicella. The disease can cause presentation ranging from mild symptoms to varicella pneumonia, hepatitis, meningoencephalitis, or fatality. If the mother develops symptoms implying varicella 4-5 days antepartum to 2 days postpartum, the mortality rate of the baby may reach 20%. We report a case of neonatal varicella from maternal varicella. The pa…
  • Zoster sine herpete: a review. [Review]
    Korean J Pain. 2020 Jul 01; 33(3):208-215.Zhou J, Li J, … Cao S
  • Zoster sine herpete (ZSH) is one of the atypical clinical manifestations of herpes zoster (HZ), which stems from infection and reactivation of the varicella-zoster virus (VZV) in the cranial nerve, spinal nerve, viscera, or autonomic nerve. Patients with ZSH display variable symptoms, such as neuralgia, however, different from HZ, ZSH show no zoster, which makes clinical diagnosis difficult. ZSH …
  • Intratonsillar Detection of 27 Distinct Viruses: A Cross-Sectional Study. [Journal Article]
    J Med Virol. 2020 Jun 30 [Online ahead of print]Silvoniemi A, Mikola E, … Jartti T
  • CONCLUSIONS: This study comprehensively reports a cross-sectional view of intratonsillar virus infections in elective tonsillectomy patients in a wide age range cohort. Tonsils are a major virus reservoir for distinct herpes and respiratory viruses without a positive association with tonsillar disease or respiratory symptoms. This article is protected by copyright. All rights reserved.
  • Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses. [Journal Article]
    J Vis Exp. 2020 Jun 14Laval K, Maturana CJ, Enquist LW
  • This protocol describes a footpad inoculation model used to study the initiation and development of neuroinflammatory responses during alphaherpesvirus infection in mice. As alphaherpesviruses are main invaders of the peripheral nervous system (PNS), this model is suitable to characterize the kinetics of viral replication, its spread from the PNS to CNS, and associated neuroinflammatory responses…
  • Varicella zoster virus in inflammatory bowel disease patients: what every gastroenterologist should know. [Journal Article]
    J Crohns Colitis. 2020 Jun 27 [Online ahead of print]Schreiner P, Mueller NJ, … Biedermann L
  • Primary Varicella Zoster virus (VZV) infection results in varicella (chickenpox) while its reactivation results in herpes zoster (HZ; shingles). Patients with Inflammatory Bowel Disease (IBD) are susceptible to complications of primary VZV infection and have an increased risk of HZ. Concerns of VZV and HZ infection in the IBD population has been highlighted by the emergence of JAK-inhibitors and …
  • Paediatrics in Theresienstadt ghetto. [Journal Article]
    Cent Eur J Public Health. 2020 Jun; 28(2):155-160.Horáčková K, Ševčovičová A, … Zaviš M
  • The main objective of this study is to describe the most common childhood diseases occurring in the Theresienstadt ghetto during the Second World War as well as applied anti-epidemic measures. A partial objective is to describe medical and nursing care of sick child prisoners. The data was obtained by the method of synthesis of primary and secondary data with the highest importance after adequate…
  • Relapsing symmetric livedo reticularis in a patient with COVID-19 infection. [Letter]
    J Eur Acad Dermatol Venereol. 2020 Jun 25 [Online ahead of print]Verheyden M, Grosber M, … Velkeniers B
  • During the Coronavirus 2019 (COVID-19) pandemic, several associated skin conditions were reported in infected patients, including; urticaria [1], exanthema [1], erythema multiforme [2], chickenpox-like vesicles [1], pityriasis rosea [3], herpes simplex reactivation [4], erythema nodosum like Sweet's syndrome [5], Symmetrical Drug-Related Intertriginous and Flexural Exanthema [6], petechial rash […
  • Herpes zoster ophthalmicus with ocular involvement in overtreated hyperthyroidism. [Case Reports]
    Indian J Ophthalmol. 2020 Jul; 68(7):1457-1458.Khurana S, Gupta PC, … Ram J
  • A 25-year-old man, with a history of hyperthyroidism presented with herpes zoster ophthalmicus (HZO) with neurotrophic ulcer and superadded infection 4 weeks after a sudden decrease in his thyroid hormones, caused by overtreatment of hyperthyroidism and radioactive iodine therapy. He underwent lateral tarsorrhaphy and was started on conservative treatment for the ulcer. The ulcer had resolved aft…
  • Disseminated herpes zoster with acute encephalitis in an immunocompetent elderly man. [Journal Article]
    BMJ Case Rep. 2020 Jun 24; 13(6)Oh JH, Tummala S, Husnain MG
  • Varicella-zoster virus (VZV) encephalitis typically occurs in immunosuppressed populations such as in patients with HIV/AIDS, transplantation and autoimmune disease. However, it can also occur in healthy hosts. We present the case of an immunocompetent patient who presented with a clinical picture of VZV encephalitis with the sole precipitating factor of advanced age. We want to stress the import…
  • Stop, think SCORTCH: rethinking the traditional 'TORCH' screen in an era of re-emerging syphilis. [Review]
    Arch Dis Child. 2020 Jun 25 [Online ahead of print]Penner J, Hernstadt H, … Lyall H
  • CONCLUSIONS: The traditional 'TORCH screen' focuses on serology-specific investigations, often omits important direct diagnostic testing of the infant, and fails to consider emerging and re-emerging congenital infections. In recognition of syphilis as a re-emerging pathogen and the overlapping clinical presentations of various infectious aetiologies, we advocate for a broader outlook using the SCORTCH diagnostic approach.
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