Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.
(vascular tuft)
303 results
  • Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity. [Journal Article]
    J Clin Invest. 2019 12 02; 129(12):5204-5218.Hu J, Bibli SI, … Fleming I
  • Polyunsaturated fatty acids such as docosahexaenoic acid (DHA) positively affect the outcome of retinopathy of prematurity (ROP). Given that DHA metabolism by cytochrome P450 and soluble epoxide hydrolase (sEH) enzymes affects retinal angiogenesis and vascular stability, we investigated the role of sEH in a mouse model of ROP. In WT mice, hyperoxia elicited tyrosine nitration and inhibition of sE…
  • Silver nanoparticle-induced nephrotoxicity in Clarias gariepinus: physio-histological biomarkers. [Journal Article]
    Fish Physiol Biochem. 2019 Dec; 45(6):1895-1905.Mahmoud UM, Mekkawy IAA, … Sayed AEH
  • The present study investigates the nephrotoxic effects of two acute doses of silver nanoparticles (AgNPs) and silver nitrate (AgNO3) on the African catfish, Clarias gariepinus, using biochemical, histochemical, and histopathological changes as biomarkers. AgNP-induced impacts were recorded in some of these characteristics on the bases of their size (20 and 40 nm) and concentration (10 and 100 μg/…
  • Systemic Rho-kinase inhibition using fasudil in mice with oxygen-induced retinopathy. [Journal Article]
    Graefes Arch Clin Exp Ophthalmol. 2019 Aug; 257(8):1699-1708.Brockmann C, Corkhill C, … Joussen AM
  • CONCLUSIONS: In conclusion, our findings support that daily systemic application of fasudil does not decrease retinal neovascularization in rodents with oxygen-induced retinopathy. The results of our study together with the controversial results on the effects of different ROCK inhibitors from the literature makes it apparent that effects of ROCK inhibition are more complex, and further studies are necessary to analyze its potential therapeutic effects.
  • 53BP1 Deficiency Promotes Pathological Neovascularization in Proliferative Retinopathy. [Journal Article]
    Thromb Haemost. 2019 Mar; 119(3):439-448.Troullinaki M, Garcia-Martin R, … Economopoulou M
  • The replication stress inflicted on retinal endothelial cells (ECs) in the context of hypoxia-induced pathological neovascularization during proliferative retinopathy is linked with activation of the deoxyribonucleic acid (DNA) repair response. Here, we studied the effect of deficiency of the DNA damage response adaptor 53BP1, which is an antagonist of homologous recombination (HR), in the contex…
  • Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy. [Journal Article]
    J Pharmacol Sci. 2018 Nov; 138(3):203-208.Iizuka N, Morita A, … Nakahara T
  • Pathological retinal angiogenesis contributes to the pathogenesis of several ocular diseases. Valproic acid, a widely used antiepileptic drug, exerts anti-angiogenic effects by inhibiting histone deacetylase (HDAC). Herein, we investigated the effects of valproic acid and vorinostat, a HDAC inhibitor, on pathological retinal angiogenesis in mice with oxygen-induced retinopathy (OIR). OIR was indu…
  • Renal Involvement in Antiphospholipid Syndrome. [Review]
    Front Immunol. 2018; 9:1008.Turrent-Carriles A, Herrera-Félix JP, Amigo MC
  • Antiphospholipid syndrome is a complex autoimmune disease, characterized by the presence of vascular thrombosis, obstetric, hematologic, cutaneous, and cardiac manifestations. Renal disease in patients with antiphospholipid syndrome was not recognized in the first descriptions of the disease, but later on, the renal manifestations of the syndrome have been investigated widely. Renal manifestation…
  • Diabetic bone lesions: a study on 38 known modern skeletons and the implications for forensic scenarios. [Journal Article]
    Int J Legal Med. 2019 Jul; 133(4):1225-1239.Biehler-Gomez L, Castoldi E, … Cattaneo C
  • Diabetes mellitus is a condition with severe and life-threatening complications and epidemic proportions worldwide. The study of diabetes on bones can provide crucial information to the forensic practice, the archeological field and medical research. In this paper, the authors report and discuss the lesions observed on the skeletons of 38 individuals (plus 11 negative control samples) of the CAL …
  • Acute Compartment Syndrome of the Foot Due To Frostbite: Literature Review and Case Report. [Case Reports]
    J Foot Ankle Surg. 2018 Mar - Apr; 57(2):382-387.Brandão RA, St John JM, … Burns PR
  • Acute compartment syndrome of the foot and ankle is a relatively rare clinical finding. Lower extremity compartment syndrome is customarily due to vascular or orthopedic traumatic limb-threatening pathologic issues. Clinical correlation and measurement of intracompartmental pressure are paramount to efficient diagnosis and treatment. Delayed treatment can lead to local and systemically adverse co…
  • Post-infectious acute glomerulonephritis with podocytopathy induced by parvovirus B19 infection. [Case Reports]
    Pathol Int. 2018 Mar; 68(3):190-195.Hara S, Hirata M, … Kawano M
  • Human parvovirus B19 infection causes a variety of glomerular diseases such as post-infectious acute glomerulonephritis and collapsing glomerulopathy. Although each of these appears independently, it has not been fully determined why parvovirus B19 provokes such a variety of different glomerular phenotypes. Here, we report a 68-year-old Japanese man who showed endocapillary proliferative glomerul…
  • Spatial distribution of CD115+ and CD11b+ cells and their temporal activation during oxygen-induced retinopathy in mice. [Journal Article]
    Graefes Arch Clin Exp Ophthalmol. 2018 Feb; 256(2):313-323.Brockmann C, Dege S, … Joussen AM
  • CONCLUSIONS: Using two different approaches to monitor MP/MG cells, our findings demonstrated that MP/MG concentrate within pathologically vascularized areas during OIR. We were able to clarify that reactive changes of CD11b+ cell distribution to OIR primarily occur in the deep retinal layers. Furthermore, we found the highest proportion of activated CD11b+ cells in regions with pathologic neovascularization processes. Our findings support previous reports about activated MP/MG guiding revascularization in avascular areas and playing a key role in the formation and regression of neovascular tufts.
New Search Next