- Fruits and vegetables consumption and the risk of gallstone diasease: A systematic review and meta-analysis. [Journal Article]
- MMedicine (Baltimore) 2019; 98(28):e16404
- CONCLUSIONS: This study suggests vegetables and fruits consumption is correlated with a significantly reduced risk of gallstone disease.
- Evaluation of pharmacological and toxic effects of ethanolic extract of radish pods in albino rabbits: A biochemical and histopathological study. [Journal Article]
- PJPak J Pharm Sci 2019; 32(3 (Supplementary)):1275-1279
- Radish pods are known as vegetable eaten as a part of diet. Though the pharmacologic potential of radish has been well known but there are fewer reports regarding pharmacological and toxic effects of…
Radish pods are known as vegetable eaten as a part of diet. Though the pharmacologic potential of radish has been well known but there are fewer reports regarding pharmacological and toxic effects of radish pods. On account of this reason, the current study was aimed to evaluate the pharmacological and toxic effects of ethanol extract of Raphanus caudatus (radish pods) in rabbits after 60 days of administration. The plant extract was administered in 250, 500 and 1000mg/kg doses and effect was observed on hepatic, renal, cardiac and lipid profile. The extract was found to be hepatoprotective, nephroprotective and cardioprotective. Also it showed hypocholestrolemic potential at 1000 mg/kg. However at higher doses the extract presented chronic gastritis. Conversely, no indication of histological alterations was seen in other vital organs such as liver, kidneys, heart. Thus there is critical requirement to identify toxic constituent/s inducing gastritis so that safety profile of the plant can be established for effective therapeutic use.
- Contamination of foods with arsenic and mercury in Iran: a comprehensive review. [Journal Article]
- ESEnviron Sci Pollut Res Int 2019 Jul 13
- Human and animals are exposed to heavy metals such as arsenic (As) and mercury (Hg) through atmospheric depositions, industrial effluents, chemical pesticides and fertilizers, erosion of geological b…
Human and animals are exposed to heavy metals such as arsenic (As) and mercury (Hg) through atmospheric depositions, industrial effluents, chemical pesticides and fertilizers, erosion of geological beds, and mining wastes which can result in the contamination of food chains. The aim of the current study was to review the available papers reporting contamination levels of As and Hg in commonly consumed foods in Iran. A descriptive search was carried out with specific keywords and entry criteria in databases of Science-Direct, PubMed, Scopus, Google Scholar, and Scientific Iranian Database (SID) published from January 2000 to July 2018. All articles were assessed by two reviewers, and final decision was made through discussions or a third reviewer arbitration. The articles were categorized based on the type of food groups including rice, fruit, vegetable, fish, seafood, drinking water, tea, and miscellanies. Of 221 identified articles on As and Hg contaminations in foods, 92 articles were selected using defined criteria. Published articles were reviewed to report contamination (mean and rate) of each food group in Iran. Results showed that rice and fish included the highest contamination rates of As and Hg, respectively. In general, As and Hg contents in Iranian foods cause serious health concerns due to the consumption quantities of the main foods. Further risk-based surveillance studies must be carried out to decrease exposure to As and Hg from dietary and non-dietary sources.
- Concentrations and distributions of polycyclic aromatic hydrocarbon in vegetables and animal-based foods before and after grilling: Implication for human exposure. [Journal Article]
- STSci Total Environ 2019 Jul 05; 690:965-972
- The effects of grilling on health risks posed by polycyclic aromatic hydrocarbons (PAHs) in food remain poorly understood. The changes of concentrations, distributions, and risks of PAHs in vegetable…
The effects of grilling on health risks posed by polycyclic aromatic hydrocarbons (PAHs) in food remain poorly understood. The changes of concentrations, distributions, and risks of PAHs in vegetables and animal-based foods before and after grilling were investigated in this study. The sum of 16 (∑16) PAH concentrations in grilled vegetables and grilled animal-based foods were 60.4-1936 and 69.1-4668 ng/g, respectively. Grilling markedly increased the ∑16 PAH concentrations in most foods analyzed. Grilling clearly increased the low-molecular-weight PAH contributions to the ∑16 PAH concentrations in vegetables but increased the heavier PAH contributions to the ∑16 PAH concentrations in some animal-based foods. With the grilling, the total benzo[a]pyrene-equivalent concentrations of the 16 PAHs in Chinese chives and enoki mushrooms and most animal-based foods were improved significantly. Source assessments indicated that environmental sources contributed PAHs to the raw foods and high-temperature pyrolysis during grilling contributed large proportions of the PAHs in the grilled foods. The carcinogenic risks to humans from the exposure of PAHs in vegetables and animal-based foods were estimated. Grilling increased the total risks of PAHs in vegetables and animal-based foods by factors of 3.12 and 5.49, respectively. Total risks of PAHs in the 11 foods were 3.43 times higher when the foods were grilled than when raw. The results suggested that the negative effects of grilling on human health should be of great concern.
- Determination of glycerophospholipids in vegetable edible oils: Proof of concept to discriminate olive oil categories. [Journal Article]
- FCFood Chem 2019 Jul 06; 299:125136
- Glycerophospholipids (GPLs) constitute a chemical family within the saponifiable fraction of vegetable oils. GPLs have been scarcely studied in edible oils owing to the lack of sensitive and selectiv…
Glycerophospholipids (GPLs) constitute a chemical family within the saponifiable fraction of vegetable oils. GPLs have been scarcely studied in edible oils owing to the lack of sensitive and selective analytical methods. We have developed a method for identification, confirmation and relative quantitation of GPLs in vegetable oils. The method is based on solid-phase extraction (SPE) for isolation of GPLs and determination by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). As proof of concept, the approach has been applied to characterize GPLs in different olive oil categories, thus revealing compositional changes, which could be explained by factors such as the quality of fruits and the extraction process. Families such as glycerophosphatidic acids and phosphatidylglycerides are remarkable because of their capability to discriminate virgin olive oils from the rest of categories. These results open a door to additional studies targeted at the identification of olive oil quality by monitoring these lipids.
- Dietary pattern, dietary total antioxidant capacity, and dyslipidemia in Korean adults. [Journal Article]
- NJNutr J 2019 Jul 13; 18(1):37
- CONCLUSIONS: This study provides basic data for the lipid-lowering effect of dietary TAC and its interaction with dietary patterns. Further study will be needed to investigate the association between dietary TAC and dietary patterns with other diseases like metabolic syndrome, cardiovascular disease, or cancer.
- Temperature and composition induced morphology transition of Cerberus emulsion droplets. [Journal Article]
- JCJ Colloid Interface Sci 2019 Jul 08; 554:210-219
- Various advanced geometries are endowed by the unique structure of "three rooms" of immiscible oils composing the Cerberus droplets. Adjustable interfacial properties and tunable volume ratio in the …
Various advanced geometries are endowed by the unique structure of "three rooms" of immiscible oils composing the Cerberus droplets. Adjustable interfacial properties and tunable volume ratio in the four-liquid system render it possible to realize the controlled morphology transition by the variation of temperature and emulsion composition.
- Natural variation in a calreticulin gene causes reduced resistance to Ca2+ deficiency-induced tipburn in Chinese cabbage (Brassica rapa ssp. pekinensis). [Journal Article]
- PCPlant Cell Environ 2019 Jul 13
- Tipburn is an irreversible physiological disorder of Chinese cabbage that decreases crop value. Because of a strong environmental component, tipburn-resistant cultivars are the only solution, althoug…
Tipburn is an irreversible physiological disorder of Chinese cabbage that decreases crop value. Because of a strong environmental component, tipburn-resistant cultivars are the only solution, although tipburn resistance genes are unknown in Chinese cabbage. We studied three populations of Chinese cabbage over four growing seasons under field conditions; (1) 194 diverse inbred lines, (2) a doubled haploid (DH100) population, and (3) an F2 population. The 194 lines were genotyped using SNP (single nucleotide polymorphism) markers, and genome-wide-association (GWA) mapping showed that 24 gQTLs were significantly associated with tipburn disease index (DI). Analysis of the DH100 and F2 populations identified a shared tipburn-associated locus, gqbTRA06, that was found to cover the region defined by one of the 24 gQTLs. Of 35 genes predicted in the 0.14-Mb QTL region, Bra018575 (calreticulin family protein, BrCRT2) showed higher expression levels during disease development. We cloned the two BrCRT2 alleles from tipburn-resistant (BrCRT2R) and -susceptible (BrCRT2S) lines, and identified a 51-bp deletion in BrCRT2S . Overexpression of BrCRT2R increased Ca2+ storage in the Arabidopsis crt2 mutant and also reduced cell death in leaf tips and margins under Ca2+ -depleted conditions. Our results suggest that BrCRT2 is a possible candidate gene for controlling tipburn in Chinese cabbage.
- Improving fruit and vegetable intake attenuates the genetic association with long-term weight gain. [Journal Article]
- AJAm J Clin Nutr 2019 Jul 13
- CONCLUSIONS: Genetically associated increased BMI and body weight could be mitigated by increasing fruit and vegetable intake, and the beneficial effect of improving fruit and vegetable intake on weight management was more pronounced in individuals with greater genetic susceptibility to obesity.
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- MaMPK2 enhances MabZIP93-mediated transcriptional activation of cell wall modifying genes during banana fruit ripening. [Journal Article]
- PMPlant Mol Biol 2019 Jul 12
- Transcriptional regulation is an essential molecular machinery in controlling gene expression in diverse plant developmental processes including fruit ripening. This involves the interaction of trans…
Transcriptional regulation is an essential molecular machinery in controlling gene expression in diverse plant developmental processes including fruit ripening. This involves the interaction of transcription factors (TFs) and promoters of target genes. In banana, although a number of fruit ripening-associated TFs have been characterized, their number is relatively small. Here we identified a nuclear-localized basic leucine zipper (bZIP) TF, MabZIP93, associated with banana ripening. MabZIP93 activated cell wall modifying genes MaPL2, MaPE1, MaXTH23 and MaXGT1 by directly binding to their promoters. Transient over-expression of MabZIP93 in banana fruit resulted in the increased expression of MaPL2, MaPE1, MaXTH23 and MaXGT1. Moreover, a mitogen-activated protein kinase MaMPK2 and MabZIP93 were found to interact with MabZIP93. The interaction of MabZIP93 with MaMPK2 enhanced MabZIP93 activation of cell wall modifying genes, which was likely due to the phosphorylation of MabZIP93 mediated by MaMPK2. Overall, this study shows that MaMPK2 interacts with and phosphorylates MabZIP93 to promote MabZIP93-mediated transcriptional activation of cell wall modifying genes, thereby expanding our understanding of gene networks associated with banana fruit ripening.