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2,338 results
  • Highly effective fibrin biopolymer scaffold for stem cells upgrading bone regeneration. [Journal Article]
    Materials (Basel). 2020 Jun 17; 13(12)Creste CFZ, Orsi PR, … Ferreira RS
  • Fibrin scaffold fits as a provisional platform promoting cell migration and proliferation, angiogenesis, connective tissue formation and growth factors stimulation. We evaluated a unique heterologous fibrin biopolymer as scaffold to mesenchymal stem cells (MSCs) to treat a critical-size bone defect. Femurs of 27 rats were treated with fibrin biopolymer (FBP); FBP + MSCs; and FBP + MSC differentia…
  • Looking for Mimicry in a Snake Assemblage Using Deep Learning. [Journal Article]
    Am Nat. 2020 Jul; 196(1) Solan T, Renoult JP, … Crochet PA
  • Batesian mimicry is a canonical example of evolution by natural selection, popularized by highly colorful species resembling unrelated models with astonishing precision. However, Batesian mimicry could also occur in inconspicuous species and rely on subtle resemblance. Although potentially widespread, such instances have been rarely investigated, such that the real frequency of Batesian mimicry h…
  • The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish- A review. [Review]
    Toxicon X. 2020 Jun; 6:100025.Gorman LM, Judge SJ, … Caldwell GS
  • In comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, remain relatively uncharacterised. Envenomation reports mainly include mild symptoms consisting of noc…
  • Revealing the venomous secrets of the spider's web. [Journal Article]
    J Proteome Res. 2020 Jun 15 [Online ahead of print]Esteves FG, Dos Santos-Pinto JRA, … Palma MS
  • Orb-weaving spiders use a highly strong, sticky and elastic web to catch their prey. These web properties alone would be enough for the entrapment of prey; however, these spiders may be hiding venomous secrets in the web, which current research is revealing. Here, we provide strong proteotranscriptomic evidence for the presence of toxin/neurotoxin-like proteins, defensins and proteolytic enzymes …
  • Animal toxins - Nature's evolutionary-refined toolkit for basic research and drug discovery. [Review]
    Biochem Pharmacol. 2020 Jun 11 [Online ahead of print]Herzig V, Cristofori-Armstrong B, … King GF
  • Venomous animals have evolved toxins that interfere with specific components of their victim's core physiological systems, thereby causing biological dysfunction that aids in prey capture, defense against predators, or other roles such as intraspecific competition. Many animal lineages evolved venom systems independently, highlighting the success of this strategy. Over the course of evolution, to…
  • Extracellular vesicles in infectious diseases caused by protozoan parasites in buffaloes. [Journal Article]
    J Venom Anim Toxins Incl Trop Dis. 2020; Pontes LG, Altei WF, … Dos Santos LD
  • CONCLUSIONS: EVs from buffaloes infected with Theileria spp. were successfully isolated and characterized. This is an advance in the knowledge of host-parasite relationship that contributes to the understanding of host immune response and theileriosis evasion mechanisms. These findings may pave the way for searching new EVs candidate-markers for a better production of safe biological products derived from buffaloes.
  • Along came a spider: Medicine's most famous spider eponyms. [Journal Article]
    Clin Dermatol. 2020 Mar - Apr; 38(2):257-261.Hoenig LJ
  • Spiders have long been admired for the beauty of their webs. They are celebrated in popular culture as well as in medical eponyms. This contribution provides the historical background for three spider-related eponyms: nevus araneus (spider angioma), arachnodactyly, and the arachnoid mater. Nevus araneus was first named and described by Sir Erasmus Wilson in 1842. Arachnodactyly was described in 1…
  • Binding of Organophosphorus Nerve Agents and Their Simulants to Metal Salts. [Journal Article]
    ACS Appl Mater Interfaces. 2020 Jun 08 [Online ahead of print]Gold J, Szilvási T, … Mavrikakis M
  • Nerve agents (NAs) pose a great threat to society because they are easy to produce and are deadly in nature, which makes developing methods to detect, adsorb, and destroy them crucial. To enable development of these methods, we report the use of first principles electronic structure calculations to understand the binding properties of NAs and NA simulants on metal-salt surfaces. We report calcula…
  • StatPearls: Snake Toxicity [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Meyers Stephen E. SE Madigan Army Medical Center Tadi Prasanna P Creighton University- CHI health BOOK
  • Venomous snakes inflict considerable morbidity and mortality worldwide, although specific data on the total number of venomous snakebites globally are lacking. In the United States, approximately 7,000 to 8,000 venomous snakebites occur each year, with about 5 to 10 deaths reported per year, although there is no mandated reporting for snakebites, so these data are likely incomplete. Notably, bees…
  • Zanthoxylum nitidum (Roxb.) DC: Traditional uses, phytochemistry, pharmacological activities and toxicology. [Review]
    J Ethnopharmacol. 2020 May 31 [Online ahead of print]Lu Q, Ma R, … Li C
  • CONCLUSIONS: This article generalises the current research achievements related to Z. nitidum, which is an important medicinal material in China. Some traditional uses of Z. nitidum have been assessed by pharmacological studies. Unresolved problems remain, including molecular mechanisms underlying biological activities, pharmacokinetics, toxicology and therapeutic effect, which are still being studied and explored before Z. nitidum can be integrated into clinical medicine.
  • Scorpion venom phospholipases A2: A minireview. [Journal Article]
    Toxicon. 2020 May 29; 184:48-54.Krayem N, Gargouri Y
  • Many venomous species, including snakes, bees and scorpions, contain a variety of secreted phospholipases A2 (sPLA2) that contribute to prey digestion and venom toxicity. Based on their primary structures, the different venom sPLA2 have been classified into four groups I, II, III and IX. While the structure of sPLA2 groups II and I has been well characterized, only one crystal structure of group …
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