- Development and prospective in-patient proof-of-concept of a surface photogrammetry + CT-based volumetric motion model for lung radiotherapy. [Journal Article]Med Phys 2019MP
- CONCLUSIONS: We described the development and a proof-of-concept validation for a volumetric motion model that uses surface photogrammetry to correlate the time-varying thoraco-abdominal surface to the time-varying internal thoraco-abdominal volume. These early results indicate that the proposed approach can result in a marked improvement over 4DCT. While limited by the duration of the fluoroscopic acquisitions as well as the resolution of the acquired images, the DRF-based proof-of-concept technique developed here is model-agnostic, and therefore, has the potential to be used as an in-patient validation tool for other volumetric motion models.
- Evaluating the Knowledge of Endotracheal Cuff Pressure Monitoring Among Critical Care Providers by Palpation of Pilot Balloon and By Endotracheal Tube Cuff Manometer. [Journal Article]Cureus 2019; 11(7):e5061C
- Introduction Mishandled endotracheal cuff pressure may either make ventilation difficult or cause damage to the airway. Therefore, the aim of this audit was to assess the knowledge about endotracheal cuff pressure monitoring with a manometer and manual palpation of pilot balloon among critical care providers. Methods This audit includes 150 critical care providers having experience of handling en…
Introduction Mishandled endotracheal cuff pressure may either make ventilation difficult or cause damage to the airway. Therefore, the aim of this audit was to assess the knowledge about endotracheal cuff pressure monitoring with a manometer and manual palpation of pilot balloon among critical care providers. Methods This audit includes 150 critical care providers having experience of handling endotracheal tube (ETT) cuff at critical care area of National Institute of Cardiovascular Diseases (NICVD), Karachi from April 2017 to June 2017. Knowledge about endotracheal cuff pressure monitoring with the manometer and deleterious effects of mishandled ETT cuff was assessed using a self-reported questionnaire. Enrolled healthcare providers were asked to palpate the patient and cuff pressure was recorded and categorized. Results Out of 150 participants, 66 (44.0%) were doctors. Only 46 (30.67%) participants had prior knowledge about ETT cuff manometer and 110 (73.33%) had never used a manometer. Similarly only 42 (28.0%) had knowledge of hazardous effects of mishandled ETT cuff. Kappa coefficient of 0.155 with p=0.015 showed significant yet low agreement between participant prediction and the actual amount of air in cuff balloon. Agreement level was comparatively higher for staff as compared to doctors with a Kappa coefficient of 0.210 (p=0.018) vs. 0.133 (p=0.099). Conclusion In this study of knowledge and practice of ETT tube cuff pressure monitoring, we observed low levels of knowledge (30.67%), poor adherence to standard practice (73.33%) and were able to demonstrate poor agreement (Kappa coefficient 0.155; p=0.015) between the palpation method and cuff manometer measurements for assessing cuff pressure.
- Quantitative comparison between single-photon emission computed tomography and positron emission tomography imaging of lung ventilation with 99mTc-technegas and 68Ga-gallgas in patients with chronic obstructive pulmonary disease: A pilot study. [Journal Article]World J Nucl Med 2019 Jul-Sep; 18(3):251-257WJ
- The aim of this study was quantitative comparison between 68Ga-Gallgas positron emission tomography (PET) and 99mTc-Technegas single photon emission computed tomography (SPECT) for lung ventilation function assessment in patients with moderate-to-severe obstructive pulmonary disease and to identify image-derived texture features correlating to the physiologic parameters. Five patients with modera…
The aim of this study was quantitative comparison between 68Ga-Gallgas positron emission tomography (PET) and 99mTc-Technegas single photon emission computed tomography (SPECT) for lung ventilation function assessment in patients with moderate-to-severe obstructive pulmonary disease and to identify image-derived texture features correlating to the physiologic parameters. Five patients with moderate-to-severe chronic obstructive pulmonary disease with PET and SPECT lung ventilation scans were selected for this study. Threshold-based segmentations were used to compare ventilated regions between both imaging techniques. Histograms of both scans were compared to reveal main differences in distributions of radiotracers. Volumes of segmentation as well as 50 textural features measured in the pulmonary region were correlated to the forced expiratory volume in 1 s (FEV1) as the relevant physiological variable. A better peripheral distribution of the radiotracer was observed in PET scans for three out of five patients. A segmentation threshold of 27% and 31% for normalized scans, for PET and SPECT respectively, was found optimal for volume correlation with FEV1. A high correlation (Pearson correlation coefficient >0.9) was found between 16 texture features measured from SPECT and 7 features measured from PET and FEV1. Quantitative measurements revealed different tracer distribution in both techniques. These results suggest that tracer distribution patterns may depend on the cause of the pulmonary obstruction. We found several texture features measured from SPECT to correlate to FEV1.
- Archaea and Bacteria Exposure in Danish Livestock Farmers. [Journal Article]Ann Work Expo Health 2019AW
- CONCLUSIONS: Archaea levels were not neglible and appeared to vary greatly between farm types. In pig farms they varied with some farm characteristics. Archaea levels appeared to depend on factors that differed from those of bacteria.
- Effect of a scaled-up neonatal resuscitation quality improvement package on intrapartum-related mortality in Nepal: A stepped-wedge cluster randomized controlled trial. [Journal Article]PLoS Med 2019; 16(9):e1002900PM
- CONCLUSIONS: These results suggest scaled-up implementation of a QI package for neonatal resuscitation can reduce intrapartum-related mortality and improve clinical care. The QI intervention package is likely to be effective in similar settings. More implementation research is required to assess the sustainability of QI interventions and quality of care.
- Oxygen data assimilation for estimating micro-organism communities' parameters in river systems. [Journal Article]Water Res 2019; 165:115021WR
- The coupling of high frequency data of water quality with physically based models of river systems is of great interest for the management of urban socio-ecosystems. One approach to exploit high frequency data is data assimilation which has received an increasing attention in the field of hydrology, but not for water quality modeling so far. We present here a first implementation of a particle fi…
The coupling of high frequency data of water quality with physically based models of river systems is of great interest for the management of urban socio-ecosystems. One approach to exploit high frequency data is data assimilation which has received an increasing attention in the field of hydrology, but not for water quality modeling so far. We present here a first implementation of a particle filtering algorithm into a community-centered hydro-biogeochemical model to assimilate high frequency dissolved oxygen data and to estimate metabolism parameters in the Seine River system. The procedure is designed based on the results of a former sensitivity analysis of the model (Wang et al., 2018) that allows for the identification of the twelve most sensible parameters all over the year. Those parameters are both physical and related to micro-organisms (reaeration coefficient, photosynthetic parameters, growth rates, respiration rates and optimal temperature). The performances of the approach are assessed on a synthetic case study that mimics 66 km of the Seine River. Virtual dissolved oxygen data are generated using time varying parameters. This paper aims at retrieving the predefined parameters by assimilating those data. The simulated dissolved oxygen concentrations match the reference concentrations. The identification of the parameters depends on the hydrological and trophic contexts and more surprisingly on the thermal state of the river. The physical, bacterial and phytoplanktonic parameters can be retrieved properly, leading to the differentiation of two successive algal blooms by comparing the estimated posterior distribution of the optimal temperature for phytoplankton growth. Finally, photosynthetic parameters' distributions following circadian cycles during algal blooms are discussed.
- Influence of Obesity on Work Ability, Respiratory Symptoms, and Lung Function in Adults with Asthma. [Journal Article]Respiration 2019; :1-9R
- CONCLUSIONS: There were indications that patients with obesity had a higher symptom burden, poorer asthma control, higher consumption of asthma medication, and reduced lung function, in particular for FVC, compared with normal-weight patients.
- Microbiological analysis of endotracheal aspirate and endotracheal tube cultures in mechanically ventilated patients. [Journal Article]BMC Pulm Med 2019; 19(1):162BP
- CONCLUSIONS: Combining microbiological culture and statistical analysis of samples collected from 81 patients who were undergoing MV in ICU, we showed that microbe found in the ETAs had high similarity with that found in the ETTs which collected at the end of the catheters. In clinical practice, ETAs analysis is easily accessible meanwhile provides a valuable information for MV patients.
- Enhancing liver tumor localization accuracy by prior-knowledge-guided motion modeling and a biomechanical model. [Journal Article]Quant Imaging Med Surg 2019; 9(7):1337-1349QI
- CONCLUSIONS: Compared to Bio-CBCT, MM-Bio-CBCT further improves the accuracy of liver tumor localization. MM-Bio-CBCT can potentially be used towards pre-treatment liver tumor localization and intra-treatment liver tumor location verification to achieve substantial radiotherapy margin reduction.
New Search Next
- [Impact of Respiratory Waveform on Gate Signal Generation on Respiratory Gated Irradiation and Evaluation Method of Respiratory Waveform to Be Used]. [Journal Article]Nihon Hoshasen Gijutsu Gakkai Zasshi 2019; 75(8):777-784NH
- CONCLUSIONS: In respiratory gated irradiation using RPM, it became clear that the gated signal is generated out of the phase set by the respiratory waveform change. Coefficient of variation of the respiratory wavelength is considered to be an indicator for evaluating the respiratory waveform to be used in the respiratory gated irradiation.