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Unbound Medicine.
(vernal conjunctivitis)
5,414 results
  • Current Knowledge in Allergic Conjunctivitis. [Journal Article]
    Turk J Ophthalmol. 2021 Feb 25; 51(1):45-54.Villegas BV, Benitez-Del-Castillo JM
  • Allergic conjunctivitis is a disease of increasing prevalence that affects both children and adults and causes significant deterioration of their quality of life and sometimes irreversible visual damage. There are various forms of the disease, some are allergen-induced such as seasonal and perennial allergic conjunctivitis, giant papillary conjunctivitis, and contact allergic blepharoconjunctivit…
  • Ectoine in the Treatment of Irritations and Inflammations of the Eye Surface. [Review]
    Biomed Res Int. 2021; 2021:8885032.Bilstein A, Heinrich A, … Mösges R
  • The ocular surface is facing various unspecific stress factors resulting in irritation and inflammation of the epithelia, causing discomfort to the patients. Ectoine is a bacteria-derived extremolyte with the ability to protect proteins and biological membranes from damage caused by extreme environmental conditions like heat, UV-light, high osmolarity, or dryness. Evidence from preclinical and cl…
  • Peanuts in the air - clinical and experimental studies. [Journal Article]
    Clin Exp Allergy. 2021 Feb 06 [Online ahead of print]Lovén Björkman S, Sederholm U, … Nilsson C
  • CONCLUSIONS: Allergic reactions to airborne peanut proteins are rare and cannot be predicted by high levels of IgE-antibodies to peanut or Ara h 2. Only small amounts of biologically active peanut proteins were detected in the air and seem unlikely to trigger moderate/severe allergic reactions.
  • Allergy and Dry Eye Disease. [Journal Article]
    Ocul Immunol Inflamm. 2021 Feb 05 [Online ahead of print]Leonardi A, Modugno RL, Salami E
  • Ocular allergy (OA) and dry eye disease (DED) are the most common ocular surface disorders with a potential severe impact on the patient's quality of life. OA and DED may coexist and have a significant clinical overlap. Therefore, clinical features commonly believed to be distinctive of OA or DED may be sometimes insufficient for a differential diagnosis. Alterations of the tear film, epithelial …
  • Factors associated with self-assessed asthma severity. [Journal Article]
    J Asthma. 2021 Jan 27 [Online ahead of print]Bouhuis D, Giezeman M, … Sundh J
  • CONCLUSIONS: Poor asthma control, allergic rhino-conjunctivitis, recent sinusitis and older age were independently associated with self-assessed moderate or severe asthma. Important implications are that comorbid conditions of the upper airways should always be considered as part of asthma management, and that elderly patients may need extra attention.
  • Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma. [Journal Article]
    Am J Clin Dermatol. 2021 Jan; 22(1):101-115.Bansal A, Simpson EL, … Ardeleanu M
  • CONCLUSIONS: Dupilumab-treated adolescents in atopic dermatitis trials had a higher incidence of conjunctivitis than placebo-treated patients, whereas overall rates of conjunctivitis among adolescents in the asthma trial were lower than in atopic dermatitis trials and were similar for dupilumab- and placebo-treated patients. Most events were mild to moderate, most recovered/resolved, and none prompted study withdrawal. These results are similar to those reported in adult trials and support a drug-disease interaction. CLINICALTRIALS.
  • Nanosystems as curative platforms for allergic disorder management. [Review]
    J Mater Chem B. 2021 Feb 25; 9(7):1729-1744.Fan PS, Sun MJ, … Liu Y
  • Allergy, IgE-mediated inflammatory disorders including allergic rhinitis, asthma, and conjunctivitis, affects billions of people worldwide. Conventional means of allergy management include allergen avoidance, pharmacotherapy, and emerging therapies. Among them, chemotherapeutant intake via oral, intravenous, and intranasal routes is always the most common mean. Although current pharmacotherapy ex…
  • Allergy to oak pollen in North America. [Journal Article]
    Allergy Asthma Proc. 2021 01 01; 42(1):43-54.Bernstein DI, Würtzen PA, … Nolte H
  • CONCLUSIONS: Allergy to oak pollen is common in North America and has a substantial clinical impact. Oak pollen allergens are cross-reactive with birch pollen allergens, which may have implications for AIT.
  • Research Progress of the Application of Hypothermia in the Eye. [Journal Article]
    Oxid Med Cell Longev. 2020; 2020:3897168.Xi L
  • Hypothermia is widely used in the medical field to protect organs or tissues from damage. Different research fields have different explanations of the protection mechanism of hypothermia. Hypothermia is also widely used in the field of ophthalmology, for example, in the eye bank, the preservation of corneal tissue and the preservation of the eyeball. Low temperature can also be applied to some op…
  • Self-Reported Allergic Rhinitis Prevalence and Related Factors in Civil Aviation Aircrew of China. [Journal Article]
    Aerosp Med Hum Perform. 2021 Jan 01; 92(1):25-31.Bai Y, Hu M, … Wang H
  • CONCLUSIONS: The prevalence of self-reported AR among civil aviation aircrew is higher than the general population in China. The severity of nasal symptoms and complications are significantly associated with quality of life and flying duties.Bai Y, Hu M, Ma F, Liu K, Xu H, Wu X, Wang H. Self-reported allergic rhinitis prevalence and related factors in civil aviation aircrew of China. Aerosp Med Hum Perform. 2021; 92(1):2531.
  • Mechanisms of Allergen Immunotherapy in Allergic Rhinitis. [Review]
    Curr Allergy Asthma Rep. 2020 Dec 12; 21(1):2.Drazdauskaitė G, Layhadi JA, Shamji MH
  • CONCLUSIONS: A comprehensive understanding of these mechanisms is necessary for optimal selection of AIT-responsive patients and monitoring treatment efficacy. Moreover, it could inspire novel and more efficient AIT approaches.
  • The spectrum of allergic ocular diseases. [Review]
    Ann Allergy Asthma Immunol. 2021 Mar; 126(3):240-254.Rodrigues J, Kuruvilla ME, … Wallace DV
  • CONCLUSIONS: Ocular allergy is frequently encountered by allergists and eye-care specialists, and despite progressively increasing incidence, it often remains underdiagnosed and, hence, untreated.
  • Allergic rhinitis. [Review]
    Nat Rev Dis Primers. 2020 12 03; 6(1):95.Bousquet J, Anto JM, … Toppila-Salmi S
  • Allergic rhinitis (AR) is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens and is one of the most common chronic conditions globally. AR often co-occurs with asthma and conjunctivitis and is a global health problem causing major burden and disability worldwide. Risk factors include inhalant and occupational allergens, as well as genetic factors. AR impairs quality of life,…
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