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297,388 results
  • The COVID-19 Pandemic: A View from New York City. [Journal Article]
    Homeopathy. 2020 Jul 14 [Online ahead of print]Masiello DJ
  • This article provides a view of homeopathic clinical practice in the New York City area in the first few months of 2020 as the coronavirus disease 2019 (COVID-19) pandemic began to evolve in the United States. Key symptoms used to generate a short list of potentially curative remedies are given, and the pandemic syndrome is viewed as appearing in stages or as having various clinical manifestation…
  • Hematolological Manifestations of COVID-19: From Cytopenia to Coagulopathy. [Review]
    Eur J Haematol. 2020 Jul 14 [Online ahead of print]Agbuduwe C, Basu S
  • s Emerging data from the management of patients with Coronavirus Disease 2019 (COVID-19) suggests multisystemic involvement, including the hemopoietic system. The hematological manifestations of COVID-19 include blood count anomalies notably lymphopenia and neutrophilia which are of prognostic significance. Hyperferritinemia and elevated lactate dehydrogenase have also been associated with increa…
  • Hard criteria for empirical theories of consciousness. [Journal Article]
    Cogn Neurosci. 2020 Jul 14 [Online ahead of print]Doerig A, Schurger A, Herzog MH
  • Consciousness is now a well-established field of empirical research. A large body of experimental results has been accumulated and is steadily growing. In parallel, many Theories of Consciousness (ToCs) have been proposed. These theories are diverse in nature, ranging from computational to neurophysiological and quantum theoretical approaches. This contrasts with other fields of natural science, …
  • Traumatic Meniscal Tears Are Associated With Meniscal Degeneration. [Journal Article]
    Am J Sports Med. 2020 Jul 14 [Online ahead of print]Wesdorp MA, Eijgenraam SM, … Reijman M
  • CONCLUSIONS: Traumatically torn menisci possess a higher degree of degeneration than intact menisci. Our results suggest that patients with a traumatic meniscal tear may already have had a certain degree of meniscal degeneration. These findings potentially challenge the classic view of traumatic versus degenerative meniscal tears.
  • A machine vision system to detect and count laying hens in battery cages. [Journal Article]
    Animal. 2020 Jul 14 [Online ahead of print]Geffen O, Yitzhaky Y, … Halachmi I
  • Manually counting hens in battery cages on large commercial poultry farms is a challenging task: time-consuming and often inaccurate. Therefore, the aim of this study was to develop a machine vision system that automatically counts the number of hens in battery cages. Automatically counting hens can help a regulatory agency or inspecting officer to estimate the number of living birds in a cage an…
  • Guiding Lights: Tissue Bioprinting Using Photoactivated Materials. [Journal Article]
    Chem Rev. 2020 Jul 14 [Online ahead of print]Lee M, Rizzo R, … Zenobi-Wong M
  • Photoactivated materials have found widespread use in biological and medical applications and are playing an increasingly important role in the nascent field of three-dimensional (3D) bioprinting. Light can be used as a trigger to drive the formation or the degradation of chemical bonds, leading to unprecedented spatiotemporal control over a material's chemical, physical, and biological propertie…
  • Design Models for Single Patient Rooms Tested for Patient Preferences. [Journal Article]
    HERD. 2020 Jul 14 [Online ahead of print]van Oel CJ, Mlihi M, Freeke A
  • Using 3D design models, this study aims to better involve patients in the design of hospitals by investigating what physical environmental characteristics in hospital patient rooms are valued by patients. There is a plea for shared-decision-making and collaborative design processes with representatives from healthcare and the construction sector based on evidence and end users' perspectives. Exis…
  • Functions of the Plasminogen Receptor, Plg-RKT. [Review]
    J Thromb Haemost. 2020 Jul 13 [Online ahead of print]Miles LA, Vago JP, … Parmer RJ
  • Plg-RKT , is a structurally unique transmembrane plasminogen receptor with both N- and C-terminal domains exposed on the extracellular face of the cell. Its C-terminal lysine functions to tether plasminogen to cell surfaces. Over expression of Plg-RKT increases cell surface plasminogen binding capacity while genetic deletion of Plg-RKT decreases plasminogen binding. Plasminogen binding to Plg-RKT…
  • Acid-Base Free Main Group Carbonyl Analogues. [Journal Article]
    Angew Chem Int Ed Engl. 2020 Jul 13 [Online ahead of print]Loh YK, Aldridge S
  • Carbonyl compounds (R 2 C=O) are cornerstones of organic chemistry. In sharp contrast, main group carbonyl analogues (R 2 E=O) derived from p -block elements from groups 13 to 15, have long been considered to be elusive species. Employment of chemical tricks such as acid/base stabilization protocols granted access to these transient species in their masked forms. However, electronic and steric ef…
  • Early Do-Not-Resuscitate Orders and Outcome After Intracerebral Hemorrhage. [Journal Article]
    Neurocrit Care. 2020 Jul 13 [Online ahead of print]Madhok DY, Vitt JR, … Hemphill JC
  • CONCLUSIONS: The use of early DNR orders for ICH continues to be a strong predictor of in-hospital mortality. However, patients treated at hospitals with an overall high or low use of early DNR had similar relative risks of death whether or not there was an early DNR order, suggesting that such orders may not be a proxy for less aggressive care as seen previously.
  • Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease. [Journal Article]
    Computation (Basel). 2020 Jun; 8(2)Qiao Z, Zhang H, … Chen Q
  • Since the outbreak of the 2019 novel coronavirus disease (COVID-19), the medical research community is vigorously seeking a treatment to control the infection and save the lives of severely infected patients. The main potential candidates for the control of viruses are virally targeted agents. In this short letter, we report our calculations on the inhibitors for the SARS-CoV-2 3CL protease and t…
  • The molecular virology of Coronaviruses. [Review]
    J Biol Chem. 2020 07 13 [Online ahead of print]Hartenian E, Nandakumar D, … Glaunsinger BA
  • Few human pathogens have been the focus of as much concentrated worldwide attention as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), the cause of COVID-19. Its emergence into the human population and ensuing pandemic came on the heels of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV),  two other highly pathogenic…
  • Neuroimmune mechanisms and sexual dimorphism in the pathophysiology of mental disorders. [Journal Article]
    J Pharmacol Exp Ther. 2020 Jul 13 [Online ahead of print]Kokkosis AG, Tsirka SE
  • Innate and adaptive immune mechanisms have emerged as critical regulators of CNS homeostasis and mental health. A plethora of immunological factors have been reported to interact with emotion- and behavior-related neuronal circuits, modulating susceptibility and resilience to mental disorders. However, it remains unclear whether immune dysregulation is a cardinal causal factor, or an outcome of t…
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