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284,075 results
  • Domain-general and domain-specific computations in single word processing. [Journal Article]
    Neuroimage 2019; :116112Klimovich-Gray A, Bozic M
  • Language comprehension relies on a multitude of domain-general and domain-specific cognitive operations. This study asks whether the domain-specific grammatical computations are obligatorily invoked whenever we process linguistic input. Using fMRI and three complementary measures of neural activity, we tested how domain-general and domain-specific demands of single word comprehension engage corti…
  • Trends in Endoscopic Mucosal Resection for Nonmalignant Colorectal Polyps in the United States. [Journal Article]
    Gastrointest Endosc 2019Yu JX, Lin JL, … Kaltenbach T
  • CONCLUSIONS: EMR is increasingly used in the United States, although there is significant regional variation. The rates of adverse events after EMR and polypectomies were low and stable, confirming the continuing safety of EMR procedures. A better understanding of the regional barriers and facilitators may improve the use of EMR as the standard management for benign colorectal lesions throughout the United States.
  • Technical Note: Characterization of X-ray beam profiles for a fluoroscopic system incorporating copper filtration. [Journal Article]
    Med Phys 2019Wunderle KA, Godley AR, … Dong FF
  • CONCLUSIONS: This study investigated and characterized 2-dimensional radiation dose deposition in water from X-ray beam spectra commonly used by modern fluoroscopes in interventional procedures. This knowledge can be applied to manual dosimetry calculations or can be used to refine the accuracy of automated dose mapping tools or Monte Carlo simulations of the radiation dose to soft tissue within the X-ray field and to tissue adjacent to the primary beam. Additionally, this study illustrates a substantial reduction of the anode heel effect by using moderate amounts of additional copper filtration to harden the X-ray beam spectrum. This article is protected by copyright. All rights reserved.
  • Two distinct actin waves correlated with turns-and-runs of crawling microglia. [Journal Article]
    PLoS One 2019; 14(8):e0220810Yang TD, Park K, … Lee KJ
  • Freely crawling cells are often viewed as randomly moving Brownian particles but they generally exhibit some directional persistence. This property is often related to their zigzag motile behaviors that can be described as a noisy but temporally structured sequence of "runs" and "turns." However, its underlying biophysical mechanism is largely unexplored. Here, we carefully investigate the collec…
  • Superparamagnetic iron oxide nanoparticles (SPIONs) modulate hERG ion channel activity. [Journal Article]
    Nanotoxicology 2019; :1-13Gualdani R, Guerrini A, … Sangregorio C
  • Superparamagnetic iron oxide nanoparticles (SPIONs) are widely used in various biomedical applications, such as diagnostic agents in magnetic resonance imaging (MRI), for drug delivery vehicles and in hyperthermia treatment of tumors. Although the potential benefits of SPIONs are considerable, there is a distinct need to identify any potential cellular damage associated with their use. Since huma…
  • Acupuncture for chronic hepatitis B. [Review]
    Cochrane Database Syst Rev 2019; 8:CD013107Kong Z, Liang N, … Liu JP
  • CONCLUSIONS: The clinical effects of acupuncture for chronic hepatitis B remain unknown. The included trials lacked data on all-cause mortality, health-related quality of life, serious adverse events, hepatitis-B related mortality, and hepatitis-B related morbidity. The vast number of excluded trials lacked clear descriptions of their design and conduct. Whether acupuncture influences adverse events considered not to be serious is uncertain. It remains unclear if acupuncture affects HBeAg, and if it is associated with reduction in detectable HBV DNA. Based on available data from only one or two small trials on adverse events considered not to be serious and on the surrogate outcomes HBeAg and HBV DNA, the certainty of evidence is very low. In view of the wide usage of acupuncture, any conclusion that one might try to draw in the future should be based on data on patient and clinically relevant outcomes, assessed in large, high-quality randomised sham-controlled trials with homogeneous groups of participants and transparent funding.
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