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64,083 results
  • Virtual screening based on molecular docking of possible inhibitors of Covid-19 main protease. [Journal Article]
    Microb Pathog. 2020 Jun 30 [Online ahead of print]Marinho EM, Batista de Andrade Neto J, … Nobre Júnior HV
  • Coronavirus (COVID-19) is an enveloped RNA virus that is diversely found in humans and that has now been declared a global pandemic by the World Health Organization. Thus, there is an urgent need to develop effective therapies and vaccines against this disease. In this context, this study aimed to evaluate in silico the molecular interactions of drugs with therapeutic indications for treatment of…
  • Allocentric coordinate spatial representations are impaired in aMCI and Alzheimer's Disease Patients. [Journal Article]
    Behav Brain Res. 2020 Jun 30 [Online ahead of print]Ruggiero G, Ruotolo F, … Iachini T
  • Research has reported deficits in egocentric (subject-to-object) and mainly allocentric (object-to-object) spatial representations in the early stages of the Alzheimer's disease (eAD). To identify early cognitive signs of neurodegenerative conversion, several studies have shown alterations in both reference frames, especially the allocentric ones in amnestic-Mild Cognitive Impairment (aMCI) and e…
  • Adaptive Fuzzy Asymptotic Tracking for Nonlinear Systems With Nonstrict-Feedback Structure. [Journal Article]
    IEEE Trans Cybern. 2020 Jul 03; PPLiang Y, Li YX, … Hou Z
  • In this article, the tracking control problems of the nonlinear nonstrict-feedback systems are considered. By combining the backstepping technique and bound estimation method, a novel nonlinear adaptive asymptotical control law is proposed, which offsets the effect of the unknown virtual control parameters and the uncertain nonlinearities. Correspondingly, an improved Lyapunov function by introdu…
  • Telemedicine in Orthopaedic Surgery: Challenges and Opportunities. [Journal Article]
    J Bone Joint Surg Am. 2020 Jul 01; 102(13):1109-1115.Makhni MC, Riew GJ, Sumathipala MG
  • Improvements in technology and a push toward value-based health care have poised the telemedicine industry for growth; however, despite the benefits of virtual care, widespread implementation had not occurred until the coronavirus 2019 (COVID-19) pandemic. Powerful barriers have hindered the widespread adoption of telemedicine, including lack of awareness, implementation costs, inefficiencies int…
  • Recent advances in orthognathic surgery. [Journal Article]
    Curr Opin Otolaryngol Head Neck Surg. 2020 Aug; 28(4):246-250.Jandali D, Barrera JE
  • CONCLUSIONS: First introduced in the 19th century, orthognathic surgery has continuously been refined. Over the last few decades, there has been increasing support for a surgery first approach in the treatment of malocclusion. MMA has revolutionized the surgical treatment of OSA and provides the best opportunity for success or cure in patients with complex obstructive patterns. Technology has enhanced the surgical process and created more efficiency for the surgeon and patient. VIDEO ABSTRACT:
  • Cinematic rendering enhancements to virtual bronchoscopy: assessment of emergent tracheal pathology. [Journal Article]
    Emerg Radiol. 2020 Jul 02 [Online ahead of print]Lin CT, Rowe S, … Fishman EK
  • Utilizing complex lighting models, cinematic rendering is a novel technique for demonstrating computed tomography data with exquisite 3D anatomic detail. The tracheal lumen, tracheal wall, and adjacent soft tissue structures are represented with photorealistic detail exceeding that of conventional volume rendering or virtual bronchoscopy techniques. We applied cinematic rendering to a spectrum of…
  • Using artificial intelligence to improve medical services in China. [Review]
    Ann Transl Med. 2020 Jun; 8(11):711.Li R, Yang Y, … Lin H
  • Artificial intelligence (AI) is one hotspot of research in the field of modern medical technology. Medical AI has been applied to various areas and has two main branches including virtual and physical. Recently, Chinese State Council issued a guideline on developing AI and indicated that the widespread application of AI will improve the level of precision in medical services and achieve the intel…
  • Sugarloaf Land in south-eastern Brazil: a tropical hotspot of lowland inselberg plant diversity. [Journal Article]
    Biodivers Data J. 2020; Paula LFA, Azevedo LO, … Forzza RC
  • Isolated monoliths of granitic and/or gneissic rock rising abruptly from the surrounding landscape are known as inselbergs. Dome-shaped inselbergs are common throughout the Atlantic Forest in south-eastern Brazil, a region known as Sugarloaf Land (SLL). This study aimed to create the first checklist of vascular plant species occurring on lowland inselbergs in SLL, with a focus on vegetation islan…
  • Repurposing old drugs to fight multidrug resistant cancers. [Review]
    Drug Resist Updat. 2020 Jun 25; 52:100713.Dinić J, Efferth T, … Tsakovska I
  • Overcoming multidrug resistance represents a major challenge for cancer treatment. In the search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a tremendous interest during the past years. Repositioning candidates have often emerged through several stages of clinical drug development, and may even be marketed, thus attracting the attention and interest of pharmaceu…
  • Landscape of Oncology Clinical Trials in Africa. [Journal Article]
    JCO Glob Oncol. 2020 Jun; 6:932-941.Odedina FT, Shamley D, … Askins N
  • CONCLUSIONS: The paucity of clinical trials in Africa will continue to magnify the global disparities of cancer in the African population. Clinical trials are needed to ensure therapeutic interventions are safe and effective in the African population. In the era of personalized and precision health, it no longer suffices to assume that drugs developed in North America, Europe, or Asia will be effective in the African population.
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