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1,029,953 results
  • Public Endowment of B Cells. [Journal Article]
    Immunity 2019; 51(4):601-603Hangartner L
  • Using a transgenic mouse strain expressing the human VH1-69 germline gene used by many broadly neutralizing antibodies to influenza A virus, Sangesland et al. show that the VH1-69 gene segment provides the essentials for mounting antibody responses against the conserved hemagglutinin stem epitope.
  • Engineering plants virus resistance: from RNA silencing to genome editing strategies. [Review]
    Plant Biotechnol J 2019Zhao Y, Yang X, … Zhang T
  • Viral diseases severely affect crop yield and quality, thereby threatening global food security. Genetic improvement of plant virus resistance is essential for sustainable agriculture. In the last decades, several modern technologies were applied in plant antiviral engineering. Here we summarized breakthroughs of the two major antiviral strategies, RNA silencing and genome editing. RNA silencing …
  • Bacteriophage MS2 displays unreported capsid variability assembling T = 4 and mixed capsids. [Journal Article]
    Mol Microbiol 2019de Martín Garrido N, Crone MA, … Aylett CHS
  • Bacteriophage MS2 is a positive-sense, single-stranded RNA virus encapsulated in an asymmetric T = 3 pseudo-icosahedral capsid. It infects Escherichia coli through the F-pilus, which it binds through a maturation protein incorporated into its capsid. Cryogenic electron microscopy has previously shown that its genome is highly ordered within virions, and that it regulates the assembly process of t…
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