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34,735 results
  • Toileting Behaviors Related to Urination in Women: A Scoping Review. [Review]
    Int J Environ Res Public Health 2019; 16(20)Wu C, Xue K, Palmer MH
  • This scoping review explores the state of science regarding women's toileting behaviors, gaps in knowledge, and areas for future research. Online databases were searched to identify papers published in English between January 2010 through July 2019; the search identified 25 articles. The Toileting Behaviors-Women's Elimination Behaviors scale has been published in four validated language versions…
  • Dysregulated NO/PDE5 signaling in the sickle cell mouse lower urinary tract: Reversal by oral nitrate therapy. [Journal Article]
    Life Sci 2019; :116922Musicki B, Anele UA, … Burnett AL
  • CONCLUSIONS: Derangement in PDE5 activity associated with basally low NO bioavailability in the bladder and urethra contributes to the molecular basis for voiding abnormalities in Sickle mice. Inorganic nitrate supplementation normalized voiding in Sickle mice through mechanisms likely involving upregulation of PDE5 activity. These findings suggest that interventions targeting dysregulatory NO/PDE5 signaling may ameliorate overactive bladder in SCD.
  • Ureterocystoplasty (bladder augmentation) in a 16 year-old boy with Goldenhar syndrome. [Case Reports]
    J Biol Regul Homeost Agents 2019 Sep-Oct; 33(5 Suppl. 1):65-67special issue: “Focus on pediatric nephrology”, Scuderi MG, … Di Benedetto V
  • The use of the dilated ureter for bladder augmentation is universally accepted for its lower rate of complications compared to the use of gastrointestinal segments. We report the case of a 16 yearold boy affected by Goldenhar syndrome who presented with neurogenic bladder with small-capacity, 5° grade vescico-ureteral reflux (VUR) with megaureter and bilateral hydronephrosis. Bladder augmentation…
  • Diagnosing Nocturnal Polyuria from a Single Nocturnal Urine Sample. [Journal Article]
    Eur Urol Focus 2019Monaghan TF, Verbalis JG, … Everaert K
  • CONCLUSIONS: Individuals with NP demonstrated higher 1 am volume (400 [interquartile range 300-515] vs 210 [160-300] ml, area under the curve [AUC]=0.843, p< 0.001, cutoff = 350 ml) and lower Uosm (274 [201-348] vs 430 [320-664] mOsm/kg H2O, AUC=0.774, p<0.001, cutoff=314 mOsm/kg H2O) than those without NP. In combining cutoffs, the criteria of either 1 am volume ≥350ml or Uosm ≤314 mOsm/kg H2O were 85% sensitive and 75% specific for NP, while criteria of both 1 am volume ≥350ml and Uosm ≤314 mOsm/kg H2O were 60% sensitive and 92% specific for NP. Comparable AUC values, sensitivities, and specificities were observed in both men and women. Limitations include post hoc design and a relatively small study sample.Individuals with NP are more likely than those without NP to produce a higher volume of more dilute urine (ie, "aquaresis") in the early hours of sleep. Analysis of easily measurable parameters of the first nocturnal void (for which 1 am values serve as a surrogate) in men and women with nocturia can predict a diagnosis of NP with a reasonably high degree of sensitivity and specificity.
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