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(warfarin)
29,242 results
  • Relationship of S/R warfarin ratio with CYP2C9 genotypes in Pakistani population. [Journal Article]
    Pak J Pharm Sci 2019; 32(4):1581-1588Qayyum A, Najmi MH, … Naveed AK
  • Warfarin is administered as a racemic preparation of R- and S-enantiomers. S-warfarin is more potent than R-warfarin, so changes in blood levels of S-warfarin affect the anticoagulant response. This study was carried out to determine the effect of CYP2C9*2 and CYP2C9*3 polymorphisms on S/R warfarin ratio. A single blood sample was collected 12-16 hours after drug administration from 170 stable pa…
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