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112,650 results
  • VarSite: disease variants and protein structure. [Journal Article]
    Protein Sci 2019Laskowski RA, Stephenson JD, … Thornton JM
  • VarSite is a web server mapping known disease-associated variants from UniProt and ClinVar, together with natural variants from gnomAD, onto protein 3D structures in the Protein Data Bank (PDB). The analyses are primarily image-based and provide both an overview for each human protein, as well as a report for any specific variant of interest. The information can be useful in assessing whether a g…
  • DALI and the Persistence of Protein Shape. [Journal Article]
    Protein Sci 2019Holm L
  • DALI is a popular resource for comparing protein structures in 3D. The software is based on distance-matrix alignment. The associated web server provides tools to navigate, integrate and organize some data pushed out by genomics and structural genomics. The server has been running continuously for the past 25 years. Structural biologists routinely use DALI to compare a new structure against previ…
  • Shark ecology, the role of the apex predator and current conservation status. [Journal Article]
    Adv Mar Biol 2019; 83:61-114Galván-Magaña F, Castillo-Geniz JL, … Tovar-Ávila J
  • Feeding studies, since traditional stomach content analysis to stable isotopes analyses, provides insights into the trophic relationship among the apex predators and the ecosystems they inhabit. The Pacific Coast of Mexico (PCM) is inhabited by 62 known species (or 12%) of living sharks, which belong to 21 families and 34 genera. We divide the Pacific Coast of Mexico (PCM) into four regions for c…
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