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6 results
  • Carbamazepine Treatment of Hyperactivity and Intrusiveness in Dementia. [Case Reports]
    Clin Neuropharmacol 2018 Jan/Feb; 41(1):43-44Stewart JT
  • Behavioral problems are seen in most patients with dementia and are often poorly characterized in the literature. We present a 70-year-old man with advanced Alzheimer disease and problematic disinhibited behaviors, including intrusiveness and Witzelsucht (disinhibited humor). These symptoms responded robustly to carbamazepine. Carbamazepine may be a useful adjunct in managing problematic behavior…
  • Pathological Joking or Witzelsucht Revisited. [Case Reports]
    J Neuropsychiatry Clin Neurosci 2016; 28(3):162-7Granadillo ED, Mendez MF
  • Humor, or the perception or elicitation of mirth and funniness, is distinguishable from laughter and can be differentially disturbed by neuropsychiatric disease. The authors describe two patients with constant joking, or Witzelsucht, in the absence of pseudobulbar affect and review the literature on pathological humor. These patients had involvement of frontal structures, impaired appreciation of…
  • Witzelsucht after right putaminal hemorrhage: a case report. [Case Reports]
    Acta Neurol Taiwan 2005; 14(4):195-200Chen YC, Tseng CY, Pai MC
  • Witzelsucht is a tendency to tell inappropriate and poor jokes. It usually occurs after a focal lesion involving orbitofrontal cortical or paramedian thalamic regions, especially on the right side. Here we report a 56-year-old man developing witzelsucht and hypersexuality after a right putaminal hemorrhage. The hematoma extended to the sublenticular part of posterior internal capsule and mesencep…
  • Hypersexuality and dysexecutive syndrome after a thalamic infarct. [Case Reports]
    Int J Neurosci 2004; 114(12):1581-90Spinella M
  • Hypersexuality can result from insults to several neuroanatomical structures that regulate sexual behavior. A case is presented of an adult male with a thalamic infarct resulting in a paramedian thalamic syndrome, consisting of hypersomnolence, confabulatory anterograde amnesia (including reduplicative paramnesia), vertical gaze deficits, and hypophonic speech. A dysexecutive syndrome also manife…
  • L'homme qui rit: inappropriate laughter and release phenomena of the frontal subdominant lobe. [Case Reports]
    Behav Med 1994; 20(1):44-6Vardi J, Finkelstein Y, … Hod I
  • Witzelsucht and moria are time-honored neurobehavioral terms. Witzelsucht is a tendency to tell inappropriate jokes, and moria is euphoric behavior. Focal right-orbitofrontal parenchymal lesion is often the anatomical substrate for these behavioral attitudes. This case report presents a patient with a longstanding witzelsucht-moria behavior. Single photon emission computerized tomography (SPECT) …
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