Coccidioidal meningitis is a rare yet life-threatening complication of disseminated Coccidioides infection, primarily affecting immunocompromised individuals. Coccidioides immitis and Coccidioides posadasii are dimorphic fungi endemic to the southwestern United States, where exposure to inhaled spores can lead to a range of clinical manifestations, including pulmonary and central nervous system (CNS) involvement. This report describes the case of a 27-year-old correctional officer with advanced human immunodeficiency virus (HIV) infection who presented with chronic headaches, altered mental status, and significant weight loss following his relocation from Arizona to Louisiana. Cerebrospinal fluid (CSF) analysis revealed slow-growing mold consistent with Coccidioides species, leading to the diagnosis of coccidioidal meningitis. This case emphasizes the importance of considering fungal meningitis in patients with compatible geographic exposure and immunosuppression.
Abstract
Case Reports
Journal Article
eng
39835071
Byrne, Patrick M., and Sanjay Shrestha. "Coccidioidal Meningitis in a Patient With HIV." Cureus, vol. 16, no. 12, 2024, pp. e76001.
Byrne PM, Shrestha S. Coccidioidal Meningitis in a Patient With HIV. Cureus. 2024;16(12):e76001.
Byrne, P. M., & Shrestha, S. (2024). Coccidioidal Meningitis in a Patient With HIV. Cureus, 16(12), e76001. https://doi.org/10.7759/cureus.76001
Byrne PM, Shrestha S. Coccidioidal Meningitis in a Patient With HIV. Cureus. 2024;16(12):e76001. PubMed PMID: 39835071.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Coccidioidal Meningitis in a Patient With HIV.
AU - Byrne,Patrick M,
AU - Shrestha,Sanjay,
Y1 - 2024/12/19/
PY - 2024/12/13/received
PY - 2024/12/19/accepted
PY - 2025/1/21/medline
PY - 2025/1/21/pubmed
PY - 2025/1/21/entrez
PY - 2024/12/19/pmc-release
KW - aids (acquired immunodeficiency syndrome)
KW - coccidioidal meningitis
KW - coccidiomycosis
KW - hiv diseases
KW - invasive fungal infections
SP - e76001
EP - e76001
JF - Cureus
JO - Cureus
VL - 16
IS - 12
N2 - Coccidioidal meningitis is a rare yet life-threatening complication of disseminated Coccidioides infection, primarily affecting immunocompromised individuals. Coccidioides immitis and Coccidioides posadasii are dimorphic fungi endemic to the southwestern United States, where exposure to inhaled spores can lead to a range of clinical manifestations, including pulmonary and central nervous system (CNS) involvement. This report describes the case of a 27-year-old correctional officer with advanced human immunodeficiency virus (HIV) infection who presented with chronic headaches, altered mental status, and significant weight loss following his relocation from Arizona to Louisiana. Cerebrospinal fluid (CSF) analysis revealed slow-growing mold consistent with Coccidioides species, leading to the diagnosis of coccidioidal meningitis. This case emphasizes the importance of considering fungal meningitis in patients with compatible geographic exposure and immunosuppression.
SN - 2168-8184
UR - https://www.unboundmedicine.com/prime/citation/39835071/Coccidioidal_Meningitis_in_a_Patient_With_HIV.
DB - PRIME
DP - Unbound Medicine
ER -
