Methamphetamine is a potent CNS stimulant that is highly addictive. Although methamphetamine use historically has been localized to the Western United States Census region, its reach has been growing, and methamphetamine use now is expanding throughout the United States and the world. Methamphetamine is now considered a definite cause of pulmonary arterial hypertension (PAH). Despite being one of the fastest growing causes of PAH, recommendations to guide the care of patients with methamphetamine-associated PAH have not been published. This review focuses on the care of patients with methamphetamine-associated PAH. It provides a practical approach to care that incorporates pharmacologic therapy in conjunction with harm reduction strategies as well as support from ancillary services such as addiction medicine and social work.
Abstract
Journal Article
Review
eng
41819484
Kolaitis, Nicholas A., et al. "How to Care for the Patient With Methamphetamine-Associated PAH." Chest, 2026.
Kolaitis NA, Barnett CF, Chin KM, et al. How to Care for the Patient With Methamphetamine-Associated PAH. Chest. 2026.
Kolaitis, N. A., Barnett, C. F., Chin, K. M., Clapham, K., Incze, M. A., Kennedy, A. J., Kingrey, J. F., Matusov, Y., Melendres-Groves, L., Rischard, F. P., & Simon, M. A. (2026). How to Care for the Patient With Methamphetamine-Associated PAH. Chest. https://doi.org/10.1016/j.chest.2026.02.016
Kolaitis NA, et al. How to Care for the Patient With Methamphetamine-Associated PAH. Chest. 2026 Mar 10; PubMed PMID: 41819484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - How to Care for the Patient With Methamphetamine-Associated PAH.
AU - Kolaitis,Nicholas A,
AU - Barnett,Christopher F,
AU - Chin,Kelly M,
AU - Clapham,Katharine,
AU - Incze,Michael A,
AU - Kennedy,Amy J,
AU - Kingrey,John F,
AU - Matusov,Yuri,
AU - Melendres-Groves,Lana,
AU - Rischard,Franz P,
AU - Simon,Marc A,
Y1 - 2026/03/10/
PY - 2025/10/10/received
PY - 2026/01/21/revised
PY - 2026/02/12/accepted
PY - 2026/3/13/pubmed
PY - 2026/3/13/medline
PY - 2026/3/12/entrez
KW - PAH
KW - amphetamine
KW - meth
KW - meth-APAH
KW - methamphetamine
KW - pulmonary arterial hypertension
JF - Chest
JO - Chest
N2 - Methamphetamine is a potent CNS stimulant that is highly addictive. Although methamphetamine use historically has been localized to the Western United States Census region, its reach has been growing, and methamphetamine use now is expanding throughout the United States and the world. Methamphetamine is now considered a definite cause of pulmonary arterial hypertension (PAH). Despite being one of the fastest growing causes of PAH, recommendations to guide the care of patients with methamphetamine-associated PAH have not been published. This review focuses on the care of patients with methamphetamine-associated PAH. It provides a practical approach to care that incorporates pharmacologic therapy in conjunction with harm reduction strategies as well as support from ancillary services such as addiction medicine and social work.
SN - 1931-3543
UR - https://www.unboundmedicine.com/prime/citation/41819484/How_to_Care_for_the_Patient_With_Methamphetamine-Associated_PAH.
DB - PRIME
DP - Unbound Medicine
ER -
