Paraganglioma is a rare form of tumor, with secretory and non-secretory variants. Due to the rare nature of gallbladder paraganglioma (GP), there are no definitive guidelines for management. We present the case of a 35-year-old female patient who presented with intermittent right upper quadrant abdominal pain. Preoperative imaging indicated the presence of gallstones within the gallbladder lumen. Laparoscopic cholecystectomy was performed, with pathology findings consistent with a paraganglioma. The gallbladder is a rare location to find paraganglionic tissue, with its rarity posing diagnostic challenges with a lack of clear differentiating criteria between benign paraganglionic tissue (paraganglionic rests) and benign paraganglioma tumors. Given the rare nature of this condition and the lack of definitive guidelines related to its diagnosis and management, additional documentation and awareness may assist other medical professionals in recognizing and treating paraganglionic tissue found in atypical sites with more clinical confidence.
Abstract
Case Reports
Journal Article
eng
42109942
Padumane, Sahana R., et al. "Non-Secretory Gallbladder Paraganglioma: an Incidental Finding On Laparoscopic Cholecystectomy." Cureus, vol. 18, no. 4, 2026, pp. e106667.
Padumane SR, Lowrey T, Amy E. Non-Secretory Gallbladder Paraganglioma: An Incidental Finding on Laparoscopic Cholecystectomy. Cureus. 2026;18(4):e106667.
Padumane, S. R., Lowrey, T., & Amy, E. (2026). Non-Secretory Gallbladder Paraganglioma: An Incidental Finding on Laparoscopic Cholecystectomy. Cureus, 18(4), e106667. https://doi.org/10.7759/cureus.106667
Padumane SR, Lowrey T, Amy E. Non-Secretory Gallbladder Paraganglioma: an Incidental Finding On Laparoscopic Cholecystectomy. Cureus. 2026;18(4):e106667. PubMed PMID: 42109942.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Non-Secretory Gallbladder Paraganglioma: An Incidental Finding on Laparoscopic Cholecystectomy.
AU - Padumane,Sahana R,
AU - Lowrey,Tricia,
AU - Amy,Eric,
Y1 - 2026/04/08/
PY - 2026/1/26/received
PY - 2026/4/8/accepted
PY - 2026/5/11/medline
PY - 2026/5/11/pubmed
PY - 2026/5/11/entrez
PY - 2026/4/8/pmc-release
KW - conventional laparoscopic cholecystectomy
KW - extra-adrenal paraganglioma
KW - gallbladder paraganglioma
KW - incidental histopathological findings
KW - non‑functional paraganglioma
SP - e106667
EP - e106667
JF - Cureus
JO - Cureus
VL - 18
IS - 4
N2 - Paraganglioma is a rare form of tumor, with secretory and non-secretory variants. Due to the rare nature of gallbladder paraganglioma (GP), there are no definitive guidelines for management. We present the case of a 35-year-old female patient who presented with intermittent right upper quadrant abdominal pain. Preoperative imaging indicated the presence of gallstones within the gallbladder lumen. Laparoscopic cholecystectomy was performed, with pathology findings consistent with a paraganglioma. The gallbladder is a rare location to find paraganglionic tissue, with its rarity posing diagnostic challenges with a lack of clear differentiating criteria between benign paraganglionic tissue (paraganglionic rests) and benign paraganglioma tumors. Given the rare nature of this condition and the lack of definitive guidelines related to its diagnosis and management, additional documentation and awareness may assist other medical professionals in recognizing and treating paraganglionic tissue found in atypical sites with more clinical confidence.
SN - 2168-8184
UR - https://www.unboundmedicine.com/prime/citation/42109942/Non-Secretory_Gallbladder_Paraganglioma:_An_Incidental_Finding_on_Laparoscopic_Cholecystectomy.
DB - PRIME
DP - Unbound Medicine
ER -
