Abstract
PURPOSE
The primary endpoint was to determine the prevalence of vestibular hypofunction in patients suffering from obstructive sleep apnea (OSA). Secondary and tertiary objectives were to determine any correlation between vestibular hypofunction and the degree of sleep apnea and/or the Dizziness Handicap Inventory (DHI) scores, and the presence of comorbidities, respectively.
METHODS
A cross-sectional prospective cohort design in which 175 adult subjects diagnosed with either probable, mild, moderate, or severe OSA were recruited. Subjects underwent complete video head impulse (vHIT) testing and a self-reported fulfilment of the DHI questionnaire. A standardized approach was applied for the interpretation and classification of the vHIT results.
RESULTS
The prevalence of vestibular hypofunction was found to be 6.9%. No significant differences in apnea-hypopnea-index (AHI) score (p = 0.26) or within AHI groups (p = 0.45) were found. Consistently, no significant differences in total DHI score (p = 0.14) or within DHI subcategories (p = 0.21) were found. OSA and an accompanying heart condition was significantly correlated to having vestibular hypofunction (p = 0.00). Subjects with vestibular hypofunction had a significantly higher number of comorbidities (p = 0.03). Furthermore, the probability of having vestibular hypofunction significantly increased with increasing numbers of accompanying comorbidities (p = 0.03).
CONCLUSION
Twelve subjects (6.9%) in a population of adult OSA patients had vestibular hypofunction. No correlation between the prevalence of vestibular hypofunction and the degree of OSA was found. Consistently, no correlation to the total- or subcategory mean DHI scores was found. A significant correlation was found between vestibular hypofunction and the presence of a heart condition as well as an increased number of comorbidities, respectively.
TY - JOUR
T1 - Vestibular function in patients diagnosed with obstructive sleep apnea.
AU - Sloth,Peter Brandt,
AU - Krogsgaard,Emil,
AU - Hougaard,Dan Dupont,
Y1 - 2026/05/11/
PY - 2025/04/06/received
PY - 2026/03/28/accepted
PY - 2026/5/12/medline
PY - 2026/5/12/pubmed
PY - 2026/5/11/entrez
JF - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JO - Eur Arch Otorhinolaryngol
N2 - PURPOSE: The primary endpoint was to determine the prevalence of vestibular hypofunction in patients suffering from obstructive sleep apnea (OSA). Secondary and tertiary objectives were to determine any correlation between vestibular hypofunction and the degree of sleep apnea and/or the Dizziness Handicap Inventory (DHI) scores, and the presence of comorbidities, respectively. METHODS: A cross-sectional prospective cohort design in which 175 adult subjects diagnosed with either probable, mild, moderate, or severe OSA were recruited. Subjects underwent complete video head impulse (vHIT) testing and a self-reported fulfilment of the DHI questionnaire. A standardized approach was applied for the interpretation and classification of the vHIT results. RESULTS: The prevalence of vestibular hypofunction was found to be 6.9%. No significant differences in apnea-hypopnea-index (AHI) score (p = 0.26) or within AHI groups (p = 0.45) were found. Consistently, no significant differences in total DHI score (p = 0.14) or within DHI subcategories (p = 0.21) were found. OSA and an accompanying heart condition was significantly correlated to having vestibular hypofunction (p = 0.00). Subjects with vestibular hypofunction had a significantly higher number of comorbidities (p = 0.03). Furthermore, the probability of having vestibular hypofunction significantly increased with increasing numbers of accompanying comorbidities (p = 0.03). CONCLUSION: Twelve subjects (6.9%) in a population of adult OSA patients had vestibular hypofunction. No correlation between the prevalence of vestibular hypofunction and the degree of OSA was found. Consistently, no correlation to the total- or subcategory mean DHI scores was found. A significant correlation was found between vestibular hypofunction and the presence of a heart condition as well as an increased number of comorbidities, respectively.
SN - 1434-4726
UR - https://www.unboundmedicine.com/prime/citation/42115425/Vestibular_function_in_patients_diagnosed_with_obstructive_sleep_apnea.
DB - PRIME
DP - Unbound Medicine
ER -
