Goal-directed therapy is not as simple as it seems.J Bone Miner Res 2026 May 12. [Online ahead of print]JB
Abstract
A case is discussed of a postmenopausal woman started on alendronate treatment based on a low T-score in the total hip. 3 yr later, her total hip score remains below -2.5, the target set by the ASBMR task force on goal-directed therapy.(1) The important question at this juncture is whether she should change to a different treatment that might result in better improvement in total hip BMD or if she should continue treatment with alendronate.
Pub Type(s)
Journal Article
Language
eng
PubMed ID
42119022
Citation
Watts, Nelson B.. "Goal-directed Therapy Is Not as Simple as It Seems." Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2026.
Watts NB. Goal-directed therapy is not as simple as it seems. J Bone Miner Res. 2026.
Watts, N. B. (2026). Goal-directed therapy is not as simple as it seems. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. https://doi.org/10.1093/jbmr/zjag080
Watts NB. Goal-directed Therapy Is Not as Simple as It Seems. J Bone Miner Res. 2026 May 12; PubMed PMID: 42119022.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Goal-directed therapy is not as simple as it seems.
A1 - Watts,Nelson B,
Y1 - 2026/05/12/
PY - 2026/01/24/received
PY - 2026/04/19/revised
PY - 2026/05/06/accepted
PY - 2026/5/12/medline
PY - 2026/5/12/pubmed
PY - 2026/5/12/entrez
JF - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
JO - J Bone Miner Res
N2 - A case is discussed of a postmenopausal woman started on alendronate treatment based on a low T-score in the total hip. 3 yr later, her total hip score remains below -2.5, the target set by the ASBMR task force on goal-directed therapy.(1) The important question at this juncture is whether she should change to a different treatment that might result in better improvement in total hip BMD or if she should continue treatment with alendronate.
SN - 1523-4681
UR - https://www.unboundmedicine.com/prime/citation/42119022/Goal-directed_therapy_is_not_as_simple_as_it_seems.
DB - PRIME
DP - Unbound Medicine
ER -


