Thrombin Generation Assay: Ready for Prime Time.Clin Lab Med 2026 Jun; 46(2):375-387.CL
Abstract
Thrombin generation assay (TGA) is a tool to assess bleeding and thrombotic risk in citrated plasma, either in the presence or absence of platelets, and several different commercial assays have been developed and actively marketed. TGA can be used for various research and clinical applications, including the identification of patients at risk of bleeding or thrombosis, as well as monitoring of treatment in at risk patients. Though current implementation is limited to specialized laboratories in university hospitals and research centers, wider implementation will require additional, large clinical trials.
Pub Type(s)
Journal Article
Review
Language
eng
PubMed ID
42140690
Citation
Riley, Paul. "Thrombin Generation Assay: Ready for Prime Time." Clinics in Laboratory Medicine, vol. 46, no. 2, 2026, pp. 375-387.
Riley P. Thrombin Generation Assay: Ready for Prime Time. Clin Lab Med. 2026;46(2):375-387.
Riley, P. (2026). Thrombin Generation Assay: Ready for Prime Time. Clinics in Laboratory Medicine, 46(2), 375-387. https://doi.org/10.1016/j.cll.2026.02.010
Riley P. Thrombin Generation Assay: Ready for Prime Time. Clin Lab Med. 2026;46(2):375-387. PubMed PMID: 42140690.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Thrombin Generation Assay: Ready for Prime Time.
A1 - Riley,Paul,
Y1 - 2026/03/11/
PY - 2026/5/16/medline
PY - 2026/5/16/pubmed
PY - 2026/5/15/entrez
KW - Clinical laboratory
KW - Coagulation assays
KW - Hemophilia
KW - Hemostasis
KW - Thrombophilia
KW - Thrombosis
SP - 375
EP - 387
JF - Clinics in laboratory medicine
JO - Clin Lab Med
VL - 46
IS - 2
N2 - Thrombin generation assay (TGA) is a tool to assess bleeding and thrombotic risk in citrated plasma, either in the presence or absence of platelets, and several different commercial assays have been developed and actively marketed. TGA can be used for various research and clinical applications, including the identification of patients at risk of bleeding or thrombosis, as well as monitoring of treatment in at risk patients. Though current implementation is limited to specialized laboratories in university hospitals and research centers, wider implementation will require additional, large clinical trials.
SN - 1557-9832
UR - https://www.unboundmedicine.com/prime/citation/42140690/Thrombin_Generation_Assay:_Ready_for_Prime_Time.
DB - PRIME
DP - Unbound Medicine
ER -
