TY - JOUR T1 - Rare Causes of Unexplained Chronic Cough in Adults. AU - Sabarinathan,Nivedita, AU - Gray,Raluca, Y1 - 2026/05/27/ PY - 2026/5/28/medline PY - 2026/5/28/pubmed PY - 2026/5/27/entrez KW - Arnold’s nerve reflex KW - CANVAS KW - Cardiac-induced cough KW - Cough KW - Endobronchial obstruction KW - Epiglottic impingement KW - Expiratory central airway collapse KW - Obstructive sleep apnea JF - Otolaryngologic clinics of North America JO - Otolaryngol Clin North Am N2 - Cough can result from a variety of etiologies, and rare pulmonary, otolaryngologic, cardiac, neurologic, medication-related, and functional conditions are often overlooked. Pulmonary etiologies, including structural airway abnormalities, endobronchial obstruction, expiratory central airway collapse, and occupational eosinophilic bronchitis, frequently require advanced imaging and bronchoscopy for diagnosis. Otolaryngologic conditions include elongated uvula, tonsillar hypertrophy, and external auditory canal pathology, which can trigger vagally mediated cough reflexes. Obstructive sleep apnea may result in chronic cough through inflammatory and reflux-mediated mechanisms. Cardiac causes include heart failure, airway compression, and arrhythmias. Neurologic, medication-induced, and functional causes should also be considered in refractory cases. SN - 1557-8259 UR - https://www.unboundmedicine.com/prime/citation/42203560/Rare_Causes_of_Unexplained_Chronic_Cough_in_Adults. DB - PRIME DP - Unbound Medicine ER -