Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil.
Clin Case Rep 2026 Jun; 14(6):e72765.

Abstract

Pigmented oral lichen planus (OLP) is a chronic, immune-mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typical white (reticular) or red (erosive) OLP features and is refractory to conventional therapy. We report a case of OLP which was successfully managed with oral mycophenolate mofetil (MMF), resulting in significant symptomatic relief and reduction of hyperpigmentation. MMF offers a safe and effective systemic option for persistent pigmented OLP.

Authors+Show Affiliations

Biswas T0009-0007-0965-3170Department of Oral Medicine and Radiology Kalinga Institute of Dental Sciences Bhubaneswar Odisha India.
Bajoria AA0000-0001-9796-9640Department of Oral Medicine and Radiology Kalinga Institute of Dental Sciences Bhubaneswar Odisha India.
Nahar N0009-0001-2555-649XDepartment of Oral Medicine and Radiology Kalinga Institute of Dental Sciences Bhubaneswar Odisha India.
Sinha P0000-0001-7316-715XDepartment of Prosthodontics Hi-Tech Dental College and Hospital Bhubaneswar Odisha India.
Sharan J0000-0002-9788-8901Department of Dentistry All India Institute of Medical Sciences Bhubaneswar Odisha India.
Basynat SKC0009-0003-6071-2931Department of Prosthodontics Kathmandu University School of Medicine Dhulikhel Nepal.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

42256961