The Prenatal Dilemma: Fever vs Acetaminophen? Navigating a Difficult Choice.
ACS Pharmacol Transl Sci 2026 Jun 12; 9(6):1584-1587.

Abstract

The clinical imperative to treat maternal hyperthermia with acetaminophen is complicated by emerging evidence of the drug's association with neurodevelopmental disorders. This article examines this risk-benefit challenge and proposes a shift toward a more nuanced, indication-specific prescribing paradigm in pregnancy.

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Authors+Show Affiliations

Darayesh MDepartment of Dermatology, Shiraz University of Medical Sciences, P.O. Box: 71348 -14336, Shiraz, Iran. Molecular Dermatology Research Center, Shiraz University of Medical Sciences, P.O. Box: 71348-14336, Shiraz, Iran.
Almahdi EE0000-0003-1742-2771Research Center for Noncommunicable Diseases,Jahrom University of Medical Sciences, P.O. Box: 74148-46199, Jahrom, Iran. Department of Advanced Medical Sciences & Technologies,Jahrom University of Medical Sciences, P.O. Box: 74148-46199, Jahrom, Iran.
Jahromi MAM0000-0001-7001-7842Research Center for Noncommunicable Diseases,Jahrom University of Medical Sciences, P.O. Box: 74148-46199, Jahrom, Iran. Department of Advanced Medical Sciences & Technologies,Jahrom University of Medical Sciences, P.O. Box: 74148-46199, Jahrom, Iran. Department of Immunology,Jahrom University of Medical Sciences, P.O. Box: 74148-46199, Jahrom, Iran.
Falahi SZoonotic Diseases Research Center,Ilam University of Medical Sciences, P.O. Box: 81364-12348, Ilam, Iran.
Kenarkoohi AZoonotic Diseases Research Center,Ilam University of Medical Sciences, P.O. Box: 81364-12348, Ilam, Iran. Department of Laboratory Sciences, School of Allied Medical Sciences, Ilam University of Medical Sciences, P.O. Box: 81364-12348, Ilam, Iran. Department of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, P.O. Box: 81364-12348, Ilam, Iran.
Abdoli A0000-0003-4326-4586Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box: 14115-131, Tehran, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

42312153