- Practice-enhancing publications about the medication-use process in 2025. [Journal Article]Am J Health Syst Pharm. 2026 Jul 14. [Online ahead of print]AJ
- CONCLUSIONS: It is important to routinely review the published literature and to incorporate significant findings into daily practice. This article assists in identifying and summarizing those most impactful. Health-system pharmacists have an active role in improving the MUP in their institution, and awareness of the significant published studies can assist in changing practice at the institutional level.
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- Abnormal dreams and night terrors with atogepant: A case series. [Journal Article]Am J Health Syst Pharm. 2026 Jul 13. [Online ahead of print]AJ
- CONCLUSIONS: Abnormal dreams and night terrors may represent an underrecognized adverse effect of atogepant. Based on this case series, the effect appears potentially reversible with discontinuation and may diminish over time in some patients who continue therapy. For patients who are taking atogepant and report sleep disturbances and dream-related symptoms, a possible correlation with atogepant should be considered. During follow-up, proactively asking about sleep disturbances and dream-related symptoms should be considered.
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- Clinical controversies in the management of candidemia in adults and children. [Journal Article]Am J Health Syst Pharm. 2026 Jul 11. [Online ahead of print]AJ
- CONCLUSIONS: Optimal candidemia management increasingly depends on individualized antifungal strategies, integration of RDTs and AFST, earlier species-directed therapy transitions, and selective evaluation for metastatic complications. Future studies are needed to better define uncomplicated candidemia, optimize treatment duration, and address evolving antifungal resistance.
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- Therapy update: An introduction to the pharmacology, safety, and efficacy of bispecific antibodies in relapsed or refractory multiple myeloma. [Journal Article]Am J Health Syst Pharm. 2026 Jul 10. [Online ahead of print]AJ
- CONCLUSIONS: The remarkable efficacy of bsAbs in RRMM combined with a maturing understanding of their toxicity profiles is fundamentally reshaping the RRMM treatment landscape.
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- Clinical determinants of discordance between estimated glomerular filtration rates based on serum creatinine vs cystatin C in critically ill patients. [Journal Article]Am J Health Syst Pharm. 2026 Jul 10. [Online ahead of print]AJ
- CONCLUSIONS: Discordance between eGFRcr and eGFRcys is common in critically ill patients. Older age, corticosteroid use, hypoalbuminemia, and delayed blood sampling increase the likelihood of substantial eGFR discordance. Recognizing these factors may help clinicians refine kidney function interpretation and optimize the dosing of renally eliminated drugs in ICU settings.
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- Pharmacists take on expanded role under new cholesterol guidelines. [Journal Article]Am J Health Syst Pharm. 2026 Jul 08; 83(14):711-712.AJ
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- Recent and anticipated novel drug approvals (Q2 2026 through Q1 2027). [Journal Article]Am J Health Syst Pharm. 2026 Jul 06. [Online ahead of print]AJ
- CONCLUSIONS: Novel therapies continue to strengthen the current drug pipeline.
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- Optimizing transitions from direct factor Xa inhibitors to unfractionated heparin therapy. [Journal Article]Am J Health Syst Pharm. 2026 Jul 04. [Online ahead of print]AJ
- CONCLUSIONS: Each hospital or health system should develop a structured approach for managing DFXaI to UFH transitions. Ideally, the transition should be managed by pharmacists and involve measurement of residual DFXaI anticoagulation to inform the timing of UFH initiation. Prospective studies are needed to better define best practices.
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- Impact of pharmacist involvement on hospital sepsis response teams. [Journal Article]Am J Health Syst Pharm. 2026 Jul 04. [Online ahead of print]AJ
- CONCLUSIONS: Pharmacist involvement in a sepsis response team is associated with improved completion of the 1-hour bundle, specifically the early administration of broad-spectrum antibiotics. Early identification of sepsis and alerting a multidisciplinary team remain barriers to optimizing treatment.
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- Attributes of centralized health-system specialty pharmacy clinics: A scoping review using the Donabedian model. [Journal Article]Am J Health Syst Pharm. 2026 Jul 03. [Online ahead of print]AJ
- CONCLUSIONS: This review highlights the variability, adaptability, and promising outcomes associated with cHSSP clinics and provides a foundation for future implementation and evaluation of these models in health systems.
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- Zoliflodacin: A novel single-dose oral antibiotic for uncomplicated urogenital gonorrhea. [Journal Article]Am J Health Syst Pharm. 2026 Jul 03. [Online ahead of print]AJ
- CONCLUSIONS: Zoliflodacin is a newly approved antibiotic with a novel mechanism of action that is highly effective for the treatment of uUGG. It is given as a single dose that can be administered orally at the time of diagnosis, thereby avoiding the intramuscular injection necessary with ceftriaxone. It is also effective against gonorrhea strains resistant to other antibiotics.
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- Implementation of a paid apprenticeship-model pharmacy technician training program. [Journal Article]Am J Health Syst Pharm. 2026 Jul 01. [Online ahead of print]AJ
- CONCLUSIONS: Formal structured training for pharmacy technicians is pertinent to ensuring patient safety and leveraging pharmacists to further patient care.
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- Iodixanol-induced acute generalized exanthematous pustulosis: Cross-reactivity to other iodinated contrast media. [Journal Article]Am J Health Syst Pharm. 2026 Jul 01. [Online ahead of print]AJ
- CONCLUSIONS: We report a rare case of AGEP induced by iodixanol and point out the potential cross-reactivity between iodixanol, iopamidol, iopromide, and iohexol. IDTs for a wide range of ICMs should be conducted to identify safe alternatives for patients.
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- Sonrotoclax. [Journal Article]Am J Health Syst Pharm. 2026 Jun 30. [Online ahead of print]AJ
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