- Maintaining Rigor in Language Model Studies: Reply. [Journal Article]Anesthesiology. 2026 Jul 15. [Online ahead of print]A
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- Maintaining Rigor in Language Model Studies: Comment. [Journal Article]Anesthesiology. 2026 Jul 15. [Online ahead of print]A
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- Effect of fractalkine signaling on neuroinflammation and neuropathic pain-like behavior in mice. [Journal Article]Anesthesiology. 2026 Jul 15. [Online ahead of print]A
- CONCLUSIONS: These findings demonstrate that enhancing CX3CL1 signaling effectively mitigates neuroinflammation and alleviates neuropathic pain-like behavior, likely through CX3CL1 signaling between neuronal and immune cells via two distinct pathways: the CX3CR1-dependent pathway mediated through the CX3CL1 N-terminus, and the TGF-β-dependent pathway mediated through the CX3CL1 C-terminus.
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- Neuromuscular Blockade Depth and Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial. [Journal Article]Anesthesiology. 2026 Jul 15. [Online ahead of print]A
- CONCLUSIONS: Moderate to deep neuromuscular blockade significantly reduced both the incidence and severity of OCR during pediatric strabismus surgery compared with minimal to shallow blockade. These findings suggest that deeper neuromuscular blockade may represent an effective strategy to attenuate OCR during extraocular muscle manipulation.
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- Greenhouse gas emissions of sevoflurane outweigh those of carrier gas and CO2 absorbers across the fresh gas flow spectrum. [Journal Article]Anesthesiology. 2026 Jul 14. [Online ahead of print]A
- CONCLUSIONS: When delivering sevoflurane in O2/air, the CO2e contribution of the carrier gas and CO2 absorbent is less than 3%, even during CCA. While CO2e is only one element of a comprehensive life cycle analysis, the presented CO2e data underscore that the key to minimizing the global warming potential of sevoflurane is lowering FGF and decreasing FETsevo.
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- Perioperative anesthetic management and procedural sedation in a child with type 1 congenital long QT Syndrome undergoing serial procedures: a case report. [Journal Article]BMC Anesthesiol. 2026 Jul 16. [Online ahead of print]BA
- CONCLUSIONS: This single-patient experience describes repeated general anesthesia and procedural sedation in a child with LQT1 without documented adverse cardiac events.
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- Regional anesthesia for hysterectomies across a large healthcare system: location matters. [Journal Article]BMC Anesthesiol. 2026 Jul 15. [Online ahead of print]BA
- CONCLUSIONS: RA receipt was not common; variability was largely attributed to facility. Patients receiving RA tended to receive more adjuncts (e.g., dexmedetomidine, ketamine, NSAID, acetaminophen, gabapentinoids), which suggests anesthesia clinicians who use RA are also those who more frequently use multimodal analgesia. Further research is needed to evaluate acute and subacute hysterectomy outcomes that accounts for the full range of anesthesia and analgesia selection, as well as clinician practice patterns and motivations for RA use.
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- A physiology-guided ketofol-based anaesthetic approach for emergency burr hole craniotomy in a child with Eisenmenger syndrome: a case report. [Journal Article]BMC Anesthesiol. 2026 Jul 16. [Online ahead of print]BA
- CONCLUSIONS: This case illustrates that ketofol-based general anaesthesia can be incorporated into a physiology-driven perioperative strategy for emergency neurosurgery in selected patients with Eisenmenger syndrome. However, favourable outcomes cannot be attributed to the anaesthetic agent alone, and conclusions regarding superiority or generalisability cannot be drawn from a single case report.
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- Suzetrigine Postmarketing Safety Signal Analysis. [Journal Article]Anesthesiology. 2026 Jul 14. [Online ahead of print]A
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- Intertransverse process and modified thoracolumbar interfascial plane blocks compared with conventional analgesia in lumbar disc herniation surgery: a randomized controlled trial. [Journal Article]BMC Anesthesiol. 2026 Jul 14. [Online ahead of print]BA
- CONCLUSIONS: Both ITP and mTLIP blocks reduced perioperative opioid requirements after lumbar disc herniation surgery, with no significant difference between the two blocks. Compared with conventional analgesia, the ITP block was additionally associated with lower postoperative pain scores and improved recovery quality. Both techniques appear to be safe, comparably effective, opioid-sparing components of multimodal analgesia.
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- Efficacy of opioid-free versus opioid-inclusive anesthesia on postoperative nausea, vomiting, and quality of recovery in patients undergoing video-assisted thoracoscopic surgery: a systematic review and meta-analysis. [Systematic Review]BMC Anesthesiol. 2026 Jul 14. [Online ahead of print]BA
- CONCLUSIONS: In selected patients undergoing VATS lung resection within multimodal pathways including regional analgesia, OFA protocols probably reduce PONV and improve early QoR compared with heterogeneous OIA regimens, while having little or no clinically important effect on acute postoperative pain. However, the independent contribution of intraoperative opioid avoidance remains uncertain owing to heterogeneity in regional analgesia, comparator opioid exposure, antiemetic strategies, and anesthetic management.
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- Zero-heat flux skin temperature tracks nasopharyngeal temperature during cardiac surgery with cardiopulmonary bypass: a prospective observational study. [Journal Article]BMC Anesthesiol. 2026 Jul 14. [Online ahead of print]BA
- CONCLUSIONS: Our results indicate that TZHF tracked TNP trends, but its large LOA limits its accuracy and reliability. Simultaneous blood temperature monitoring would enhance TZHF's effectiveness, as is currently done in cardiac surgery, where both blood temperature and TNP are monitored.
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- Expert perspectives on the requirements for implementing prehospital peripheral nerve blocks: a survey among members of the European Society of Regional Anaesthesia (ESRA). [Journal Article]
- CONCLUSIONS: While most respondents supported the concept of prehospital RA, only few indicated that such approaches are currently implemented in their local EMS systems. FICB and FNB were identified as the preferred options for managing proximal femur fractures. Key concerns regarding implementation included limited team experience, time constraints, and procedural complications such as local anesthetic systemic toxicity (LAST), emphasizing the need for structured training, clear protocols, and expert guidance to ensure safe implementation.
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- Trends in Anesthesia-associated Arterial and Pulmonary Artery Catheter Utilization: Medicaid Claims Analysis, 2018-2023. [Journal Article]Anesthesiology. 2026 Jul 14. [Online ahead of print]A
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- Intercostal versus Erector Spinae in Thoracoscopy: Reply. [Journal Article]Anesthesiology. 2026 Aug 01; 145(2):513-515.A
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