- Difficult Airway Society 2025 guidelines for management of unanticipated difficult tracheal intubation in adults: rethinking tracheal tube size for emergency scalpel cricothyroidotomy. Comment on Br J Anaesth 2025; 136: 283-307. [Letter]Br J Anaesth. 2026 Aug 06. [Online ahead of print]BJ
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- Self-reported frailty: good enough for perioperative practice? [Editorial]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
- Patient frailty is known to correlate with poor outcomes after surgery, however, routinely measuring frailty has proved an ongoing hurdle in perioperative practice. Self-reported patient frailty could represent a novel approach to the issue. Alkadari and colleagues report a largely successful experience with self-reported frailty in 531 older adults undergoing noncardiac surgery, although some ch…
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- Epigenetics, inflammation and postoperative complications: a scoping review. [Review]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
- CONCLUSIONS: DNA methylation and histone modifications are less researched epigenetic mechanisms in perioperative inflammation. Future studies should recruit patients with homogeneous surgical insults. Studies should use standard measures of inflammation to enhance generalisability, whereas experimental approaches (including transcriptomics and proteomics) could advance mechanistic understanding in exploratory studies. Future research would benefit from consistent use of validated definitions of postoperative complications to enable comparison between studies.
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- Perioperative management of patients taking sodium-glucose cotransporter 2 inhibitors: Society for perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement. Comment on Br J Anaesth 2026; 136: 1776-99. [Letter]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
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- Age-adjusted minimal alveolar concentration for sevoflurane: not so comparable after all? [Letter]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
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- Prostaglandins prevent long-lasting pain in a mouse model of chronic postsurgical pain: reconciling animal and clinical evidence. Response to Br J Anaesth 2026; 137: 344-6. [Letter]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
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- κ-Opioid receptor activation suppresses triple-negative breast cancer progression by inducing urea cycle dysfunction and mitochondrial damage in vitro and in mice. Comment on Br J Anaesth 2025; 135: 1803-15. [Letter]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
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- Socioeconomic status and mortality after acute hip fracture surgery in Sweden: a registry-based nationwide epidemiologic study. [Journal Article]Br J Anaesth. 2026 Aug 05. [Online ahead of print]BJ
- CONCLUSIONS: Individual socioeconomic status was associated with short- and long-term death after acute hip fracture surgery in Sweden, with education showing the strongest relationship. These findings support consideration of individual-level socioeconomic factors in perioperative hip fracture care at the population level.
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- Assessing impact of supervision in aerobic exercise training on fitness and clinical outcomes: a systematic review and meta-analysis. [Review]Br J Anaesth. 2026 Aug 04. [Online ahead of print]BJ
- CONCLUSIONS: Both supervised and unsupervised exercise improved 6MWT distance. Supervised high-intensity exercise programmes significantly reduced postoperative complications. Findings were limited by lack of direct comparisons between exercise groups, necessitating further research.
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- Dexmedetomidine produces more sleep-like brain activity compared with propofol in human participants. Comment on Br J Anaesth 2026; 136: 552-63. [Letter]Br J Anaesth. 2026 Aug 01. [Online ahead of print]BJ
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- EEG alpha power and delirium in the postanaesthesia care unit in older adults: is dose-corrected alpha power important? Comment on Br J Anaesth 2026; 136: 1252-62. [Letter]Br J Anaesth. 2026 Jul 31. [Online ahead of print]BJ
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- Dose-response association between intraoperative norepinephrine and postoperative acute kidney injury: a retrospective cohort study. [Journal Article]Br J Anaesth. 2026 Jul 31. [Online ahead of print]BJ
- CONCLUSIONS: Intraoperative norepinephrine exposure was independently associated with postoperative AKI, with nonlinear behaviour for unit-rate metrics and linear behaviour for time-integrated metrics, largely independent of intraoperative hypotension. The two anchors define a two-tier vigilance framework.
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- International variation in ethical approval for the SQUEEZE study: implications for global perioperative research. [Letter]Br J Anaesth. 2026 Jul 31. [Online ahead of print]BJ
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- Postoperative shivering after intraoperative methadone administration: a retrospective cohort study. [Journal Article]Br J Anaesth. 2026 Jul 31. [Online ahead of print]BJ
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- Preoperative electrocardiography for predicting cardiovascular events after noncardiac surgery: a secondary analysis of two prospective cohorts. [Journal Article]Br J Anaesth. 2026 Jul 31. [Online ahead of print]BJ
- CONCLUSIONS: Preoperative ECG findings, assessed by including conventional waveform features and the PreOpNet algorithm, provide limited incremental predictive value for cardiovascular risk assessment before noncardiac surgery.
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