- Novel surgical approach to correct late-hypotony in PreserFlo MicroShunt. [Journal Article]Br J Ophthalmol. 2026 Aug 07. [Online ahead of print]BJ
- We report a novel surgical approach for managing late hypotony in PreserFlo MicroShunt blebs. Hypotony is a well-known complication of glaucoma filtering surgery, yet treatment options for late-onset cases remain limited. We describe two cases of uveitic glaucoma presenting with hypotony several months after PreserFlo implantation. Both patients were successfully treated with a bleb-modifying pro…
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- Integrating opportunistic ocular diseases screening into general health examination in Chinese: a multicentre study. [Journal Article]Br J Ophthalmol. 2026 Aug 05. [Online ahead of print]BJ
- CONCLUSIONS: This health examination centre-based screening model is feasible, effective and affordable for detecting multiple fundus diseases in large populations. As the model is promoted and its coverage expands, screening costs may be further reduced.
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- Risk of glaucoma among patients using tadalafil for lower urinary tract symptoms: a multinational cohort study. [Journal Article]Br J Ophthalmol. 2026 Aug 04. [Online ahead of print]BJ
- CONCLUSIONS: Tadalafil was associated with increased risk of glaucoma compared with non-PDE5i in males with LUTS. Ophthalmic evaluation and follow-up may be considered, particularly in patients with risk factors for glaucoma.
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- Optic nerve compression predicts acuity loss while orbital crowding predicts field defects in patients with early-to-moderate intraorbital cavernous haemangiomas. [Journal Article]Br J Ophthalmol. 2026 Aug 04. [Online ahead of print]BJ
- CONCLUSIONS: Visual loss from orbital tumours involves two mechanical pathways: direct compression preferentially impairs central vision (VA), while orbital apex crowding predominantly affects peripheral vision (VF). Imaging metrics like ONAR and TO-ratio can effectively quantify these mechanisms. They may serve as supplementary reference indicators for evaluating visual risk and informing clinical follow-up and surgical consultation, with ONAR indicating risk to central vision and TO-ratio signalling impending field loss.
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- Intraocular foreign bodies: a systematic review and meta-analysis of clinical manifestations, diagnostic challenges and management strategies. [Journal Article]Br J Ophthalmol. 2026 Aug 04. [Online ahead of print]BJ
- CONCLUSIONS: Early diagnosis and timely surgical intervention are critical for optimising outcomes in retained IOFBs. CT and pars plana vitrectomy remain central to management, while delayed intervention increases the risk of severe complications. Standardised protocols and prospective multicentre studies are needed to strengthen evidence and improve patient care.
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- Semaglutide-associated NAION: a proposed 'two-hit' model involving buried optic disc drusen and sustained hypohydration. [Journal Article]Br J Ophthalmol. 2026 Aug 03. [Online ahead of print]BJ
- Semaglutide-associated non-arteritic anterior ischaemic optic neuropathy (NAION) mechanisms are unclear. We report a 28-year-old man with type 2 diabetes who developed right NAION 4-5 months after starting semaglutide. Multimodal imaging confirmed NAION and bilateral buried optic disc drusen. The affected eye was short, whereas the fellow eye was highly myopic and longer. Serial bioimpedance show…
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- Transcranial magnetic stimulation as a novel therapeutic approach for severe retinal degenerative diseases: a pilot study. [Journal Article]Br J Ophthalmol. 2026 Jul 31. [Online ahead of print]BJ
- CONCLUSIONS: In this exploratory pilot study, TMS treatment was associated with short-term functional visual improvements and cortical modulation in individuals with severe retinal degenerative diseases. These findings are hypothesis-generating and warrant validation through larger, randomised, masked clinical trials with longer follow-up.
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- Distribution and associated factors of outdoor time among children and adolescents: a systematic review and meta-analysis. [Journal Article]Br J Ophthalmol. 2026 Jul 28. [Online ahead of print]BJ
- CONCLUSIONS: In regions and populations with a higher prevalence of myopia, outdoor time is also relatively short. It is recommended to further promote initiatives to increase outdoor activity time in order to achieve better myopia control.
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- Incidence and risk factors for epiretinal membrane formation after intravitreal anti-VEGF injection in branch retinal vein occlusion. [Journal Article]Br J Ophthalmol. 2026 Jul 28. [Online ahead of print]BJ
- CONCLUSIONS: About one-fifth of BRVO eyes developed an ERM within one year after anti-VEGF therapy. Post-injection PVD was the most robust factor associated with ERM development, underscoring the importance of vitreoretinal interface changes in the post-treatment course.
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- Persistence of severe global sex-based inequalities in the burden of visual impairment. [Journal Article]Br J Ophthalmol. 2026 Jul 28. [Online ahead of print]BJ
- CONCLUSIONS: Global sex disparities in vision impairment remained substantial from 1990 to 2023 and are projected to continue. The strong association with GDI and GII indicates these disparities are modifiable and linked to structural factors. Gender-sensitive policies are needed to achieve equity in eye health.
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- Cross-device consistency in diabetic retinopathy grading: a comparative analysis of widefield versus standard 30-35° - the ClarusDR study. [Journal Article]Br J Ophthalmol. 2026 Jul 23. [Online ahead of print]BJ
- CONCLUSIONS: The peripheral retina alone does not show increased lesion severity, but extended UWF imaging integrating central and peripheral fields provides a more complete assessment. Extended Clarus and Optos imaging closely align with ETDRS grading while detecting additional severe cases, supporting UWF imaging as an alternative to ETDRS photography in clinical trials and practice.
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- Observation burden: why surveillance in ophthalmology deserves the same scrutiny as treatment. [Review]Br J Ophthalmol. 2026 Jul 21. [Online ahead of print]BJ
- Ophthalmology manages a substantial share of its patients through prolonged observation, spanning nearly every subspecialty, from choroidal nevi and glaucoma suspects to optic disc drusen and diabetic retinopathy. Yet surveillance schedules rarely face the scrutiny of cost, benefit and harm demanded of treatment. This article reframes observation as an intervention in its own right, with direct c…
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- Quantitative reference map of retinopathy of prematurity improves diagnostic reliability and treatment decisions. [Journal Article]Br J Ophthalmol. 2026 Jul 21. [Online ahead of print]BJ
- CONCLUSIONS: The quantitative ROP zone reference map improved reliability of zone classification and supported more consistent ETROP guideline application in this retrospective reader study.
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- Surgical outcome and late-onset complications 5 years after pars plana vitrectomy for myopic traction maculopathy. [Journal Article]Br J Ophthalmol. 2026 Jul 21. [Online ahead of print]BJ
- CONCLUSIONS: Fovea sparing is useful both for improving vision and preventing complications. We suggest that FSIP has the possible benefit of avoiding postoperative MA.
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- Global temporal trends of DR-related blindness and vision loss from 1990 to 2021: an age-period-cohort analysis of the contributions of type 1 and type 2 diabetes. [Journal Article]Br J Ophthalmol. 2026 Jul 20. [Online ahead of print]BJ
- CONCLUSIONS: Substantially different trends were observed for ASPR, period and cohort effects in recent decades for type 1 versus type 2 diabetes across different SDI.
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