- Methodological limitations in the interpretation of clinical benefit in RESHAPE-HF2. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Casting the net of the NETosis-inflammasome axis on the cardiorenal axis in diabetes. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Scratching the itch: the eNOS toolbox expands with a new post-translational regulatory pathway. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Cardiovascular disease, cancer risk, and sex: expanding the prevention agenda in cardio-oncology. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Lipoprotein(a) in Japan: when 'moderately elevated' might already mean high risk. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Prediction of left main coronary artery disease by ECG exercise stress testing: ready for clinical implementation? [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Vitronectin-driven amyloid deposition disrupts mitochondrial homeostasis via integrin-mediated pathway in a humanized mouse model of transthyretin cardiac amyloidosis. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
- CONCLUSIONS: Two reproducible ATTR-CM models that recapitulate the steadily progressive course of human disease were established. Furthermore, VTN actively drives cardiac amyloid deposition, and disruption of integrin αvβ3/FAK/Akt signalling links amyloid-ECM interactions to mitochondrial dysfunction. Therefore, modulation of integrin signalling represents a potential complementary therapeutic strategy in ATTR-CM beyond TTR suppression.
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- Sex Based Differences in Association Between Plaque Burden and Ischemia -- a CREDENCE Trial Substudy. [Journal Article]Eur Heart J Cardiovasc Imaging. 2026 Aug 11. [Online ahead of print]EH
- CONCLUSIONS: Despite having a lower overall plaque burden, women exhibit a stronger association between plaque burden and ischemia than men. Further investigation in prospective studies is warranted to better understand potential sex-related differences in CAD.
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- RUNX1-driven endothelial-to-mesenchymal transition contributes to remodelling in LMNA cardiomyopathy. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
- CONCLUSIONS: RUNX1-driven EndoMT represents a central mechanism linking LMNA mutations to fibrotic remodelling in LMNA cardiomyopathy. These findings support endothelial transcriptional reprogramming and RUNX1 signalling as potential therapeutic targets in fibrotic cardiomyopathy.
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- Staging a comeback for digitalis. [Journal Article]Eur Heart J. 2026 Aug 11. [Online ahead of print]EH
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- Tricuspid valve endocarditis caused by Campylobacter fetus bacteraemia in a 48-year old female: a case report. [Case Reports]Eur Heart J Case Rep. 2026 Aug; 10(8):ytag492.EH
- Campylobacter infections are very common overall. They typically affect the gastrointestinal tract and are usually caused by consumption of contaminated meat or water. Older people, men, and people with weakened immune systems are significantly more likely to be affected. Endocarditis caused by Campylobacter fetus, especially of the tricuspid valve, is rarely reported and not easy to diagnose.
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- From exercise to emergency-an extreme presentation of MINOCA: a case report. [Case Reports]Eur Heart J Case Rep. 2026 Aug; 10(8):ytag442.EH
- Coronary artery vasospasm (CAS) is an important, yet under-recognized cause of myocardial infarction with non-obstructive coronary arteries (MINOCA), associated with significant morbidity and mortality.
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- First use of pulsed field ablation in a patient with a deep brain stimulator: a case report. [Case Reports]Eur Heart J Case Rep. 2026 Aug; 10(8):ytag560.EH
- Pulmonary vein isolation for atrial fibrillation (AF) in patients with implanted neurostimulation devices is challenging, as established energy sources, such as radiofrequency (RF) ablation, are generally not recommended in these patients due to the risk of device interference. Pulsed field ablation (PFA) for AF offers relative myocardial selectivity and a potentially improved safety profile. How…
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- Acute progression of extrinsic outflow graft obstruction associated with interval relocation of pliable biodebris in a patient with left ventricular assist device. [Case Reports]Eur Heart J Case Rep. 2026 Aug; 10(8):ytag557.EH
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- A rare right coronary artery arising from the left anterior descending artery with a critical left main lesion: a case report. [Case Reports]Eur Heart J Case Rep. 2026 Aug; 10(8):ytag563.EH
- An anomalous right coronary artery (RCA) arising from the left anterior descending artery (LAD) is a very rare coronary variant. When a distal left main (LM)/ostial LAD culprit lesion occurs in this setting, the myocardium at risk is substantial and revascularization decisions are time critical.
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