(European Respiratory Journal[TA])
16,371 results
  • Three-dimensional micro-CT analysis of vascular remodeling and vascular pruning in pulmonary arterial hypertension. [Journal Article]
    Eur Respir J. 2026 May 21. [Online ahead of print]Aerts G, Willems L, … Godinas LER
  • CONCLUSIONS: This study provides quantitative evidence of arterial narrowing and objective loss of small intra-acinar arteries in end-stage PAH, supporting their central role in elevated PVR. Pulmonary vascular rarefaction may represent an initiating process of vascular remodeling rather than a secondary phenomenon. Heritable PAH was characterized by a higher number and more distal distribution of plexiform lesions compared to idiopathic PAH, which may contribute to its more severe phenotype.