(European Respiratory Journal[TA])
16,423 results
  • Aberrant and Ectopic Cell Populations in Restrictive Allograft Syndrome after Lung Transplantation. [Journal Article]
    Eur Respir J. 2026 Jul 09. [Online ahead of print]Leiber LM, Christian L, … Schupp JCER
  • CONCLUSIONS: Considering the multifaceted differences of RAS and idiopathic pulmonary fibrosis, we revealed a surprising general principle of an entity-spanning composition of the fibrotic niche by aberrant basaloid cells localized at the fibrotic edge, ectopic COL15A1[+] pVECs and CTHRC1[+] fibrotic fibroblasts. This suggests a flexible but cellular pathogenesis-guided transferability of potential therapeutic approaches between progressive fibrotic lung diseases.
  • A Transcriptomic Atlas of Chronic Lung Allograft Dysfunction. [Journal Article]
    Eur Respir J. 2026 Jul 02. [Online ahead of print]Beeckmans H, Kerckhof P, … Vos RER
  • CONCLUSIONS: CLAD is a spatially heterogeneous, yet molecularly continuous disease process, wherein BOS and RAS represent variable stages of a shared immunopathological continuum. Our findings support the development of lung-specific molecular classifiers to guide diagnostics and reveal novel targets for personalised therapies in transplantation.