- Racial disparities in patient outcomes following catheter-directed thrombectomy for acute pulmonary embolism. [Journal Article]Heart Lung. 2026 Jul 14; 80:102891. [Online ahead of print]HL
- CONCLUSIONS: Significant racial disparities in NACE, mortality, and bleeding were observed following CDT for acute PE. Native American patients showed numerically higher NACE, Asian/PI patients had the highest mortality, and Black patients had higher bleeding. Residual confounding by PE severity cannot be excluded given absent severity markers in the NIS. Findings highlight the need for equity-focused risk stratification and standardized peri‑procedural strategies in advanced PE.
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- Holter-detected arrhythmias and early readmission risk in acute exacerbations of COPD. [Journal Article]Heart Lung. 2026 Jul 13; 80:102888. [Online ahead of print]HL
- CONCLUSIONS: In-hospital arrhythmias are common in AECOPD but have limited overall prognostic impact. In this cohort, arrhythmia subtypes were not associated with prolonged length of stay. Early Holter monitoring may help identify patients at high risk of very early readmission and support pragmatic inpatient risk stratification.
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- Association of demographic and clinical characteristics of patients with acute pulmonary embolism and mild renal insufficiency. [Journal Article]Heart Lung. 2026 Jul 13; 80:102889. [Online ahead of print]HL
- CONCLUSIONS: APE with mild renal insufficiency exhibits distinct demographic and clinical characteristics, with a poor prognosis. Age, SCr, RVD/LVD, right ventricular enlargement, and hypertension are independent risk factors of APE complicated with mild renal insufficiency. CysC is more sensitive than SCr for early detection of glomerular filtration impairment.
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- National burden and geographic variation in healthcare utilization and expenditures among adults with heart failure in the United States (2013-2022). [Journal Article]Heart Lung. 2026 Jul 13; 79:102884. [Online ahead of print]HL
- CONCLUSIONS: Heart failure is associated with substantial and increasing healthcare utilization and expenditures in the United States, with important regional differences. These findings may inform heart failure management and care delivery strategies, particularly in strengthening outpatient and multidisciplinary care across regions.
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- Type of treating centres and outcomes among patients with out of hospital cardiac arrest: Insights from a large nationwide registry. [Journal Article]Heart Lung. 2026 Jul 11; 79:102883. [Online ahead of print]HL
- CONCLUSIONS: Management of OHCA patients at PCI-capable hospitals was associated with lower mortality. The performance of PCI and TC were also associated with better outcomes, especially in certain profiles of patients.
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- Prognostic performance of NEWS2 and sPESI scores for predicting in-hospital mortality in patients with acute pulmonary embolism. [Journal Article]Heart Lung. 2026 Jul 11; 79:102890. [Online ahead of print]HL
- CONCLUSIONS: NEWS2 is an independent predictor of in-hospital mortality in patients with acute PE and may provide incremental prognostic value beyond conventional clinical variables. Its simplicity and real-time applicability make it a useful tool for early risk stratification in emergency settings.
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- A secondary analysis of how changes in pain interference relate to changes in health-related quality of life and physical function in heart failure. [Journal Article]Heart Lung. 2026 Jul 06; 79:102881. [Online ahead of print]HL
- CONCLUSIONS: Findings supported a relationship between changes in pain interference with changes in physical function and HRQoL in HF. Further research is needed with clearly defined chronic pain and more robust pain interference measures.
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- Diagnosing heart failure through imaging. [Editorial]Heart Lung. 2026 Jun 30; :102880. [Online ahead of print]HL
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- Comparative utility of median household income, social vulnerability index, and social deprivation index in predicting heart failure-related emergency department revisits: A multi-hospital cohort study. [Journal Article]Heart Lung. 2026 Jun 23; 79:102878. [Online ahead of print]HL
- CONCLUSIONS: All three measures capture overlapping socioeconomic signals with equivalent discrimination. SVI and SDI attenuation in joint models reflects statistical redundancy rather than true inferiority; income's parsimony supports its use as a practical screening tool at discharge.
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- Predicting in-hospital mortality in AECOPD: A comparison of the mSOFA score with DECAF, Ottawa, and GOLD classifications. [Journal Article]Heart Lung. 2026 Jun 20; 79:102879. [Online ahead of print]HL
- CONCLUSIONS: mSOFA demonstrated high discriminative performance and favorable clinical net benefit for predicting in-hospital mortality in ED patients with AECOPD and may be useful for risk stratification.
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- Diagnostic accuracy of serological tests and biomarkers for hypersensitivity pneumonitis: A systematic review. [Review]Heart Lung. 2026 Jun 19; 79:102876. [Online ahead of print]HL
- CONCLUSIONS: Serological testing provides moderate diagnostic accuracy for HP with substantial variation by disease subtype, methodology, and stage. These tests should complement comprehensive multidisciplinary discussion. Positive results require clinical and radiological correlation while negative results cannot exclude HP, particularly in chronic fibrotic disease.
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- Associations of genetic risk factors and air pollution with incident pulmonary embolism: a prospective cohort study in the UK Biobank. [Journal Article]Heart Lung. 2026 Jun 19; 79:102877. [Online ahead of print]HL
- CONCLUSIONS: This investigation revealed that extended combined exposure to air pollutants was linked to an elevated incidence of PE, particularly in those with a high genetic predisposition.
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- Impaired hemostasis in mechanical circulatory support systems: Monitoring with T-TAS® 01, in vitro correction with VWF concentrates, and impact of membrane oxygenators. [Journal Article]Heart Lung. 2026 Jun 18; 79:102875. [Online ahead of print]HL
- CONCLUSIONS: MCS is associated with significant and persistent alterations in primary hemostasis. T-TAS® 01 may represent a useful tool for dynamic assessment of these changes. In vitro VWF supplementation improved functional hemostasis parameters, although its clinical implications remain to be established. Differences related to MO presence were not consistent, supporting a shared mechanism of hemostatic dysregulation across MCS devices.
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- High-performance multicenter Echocardiographic diagnostic score for Transthyretin Cardiac amyloidosis: results from the REACT-SP multicenter retrospective Cohort study. [Journal Article]Heart Lung. 2026 Jun 12; 79:102874. [Online ahead of print]HL
- CONCLUSIONS: A simple model based on age and echocardiographic parameters showed excellent diagnostic performance for ATTR-CA. These findings support the use of widely available echocardiographic measures as part of an initial diagnostic approach, although external validation is required.
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- Simplified GDMT score and all-cause readmission in patients with heart failure: A retrospective cohort study. [Journal Article]Heart Lung. 2026 Jun 11; 79:102873. [Online ahead of print]HL
- CONCLUSIONS: A higher simplified GDMT score was associated with reduced 30-day and 6-month readmissions, particularly among patients with ischemic heart failure, supporting its potential utility as a pragmatic measure of GDMT optimization.
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