- Peripheral blood neutrophil-to-lymphocyte ratio and long-term outcomes among patients surviving cardiogenic shock. [Letter]J Crit Care. 2026 Jul 10; 96:155673. [Online ahead of print]JC
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- Ventilator-associated pneumonia prevention: Past, present, perspective. [Journal Article]J Crit Care. 2026 Jul 09; 96:155678. [Online ahead of print]JC
- The prevention of ventilator-associated pneumonia (VAP) is a key part of managing critically ill patients who require invasive mechanical ventilation. Despite a reduction in exposure to mechanical ventilation, the incidence of VAP remains high, significantly impacting outcomes. In this brief review, at the light of recent meta-analyses, we examine the evolution of VAP prevention over the past few…
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- The rise of medical autonomous care, a paradigmatic turning point for military and civilian delivery of health care. [Review]J Crit Care. 2026 Jul 08; 96:155675. [Online ahead of print]JC
- CONCLUSIONS: The MAC-SOS meeting provided a forum for dialogue, sharing of ideas, and discussions on key challenges, obstacles, and opportunities that medical autonomous care technology faces from inception to clinical deployment and post-implementation surveillance. It also served as a primer for the creation of a sustainable alliance between all stakeholders, and a springboard for novel ideas and future collaborations.
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- Timing of spontaneous breathing in veno-venous extracorporeal membrane oxygenation: An exploratory analysis of intensive care outcomes. [Journal Article]J Crit Care. 2026 Jul 08; 96:155676. [Online ahead of print]JC
- CONCLUSIONS: Early spontaneous breathing was associated with higher adjusted rates of extubation and ICU discharge in an exploratory analysis; however, these findings should be interpreted cautiously because of residual confounding, selection bias, and immortal-time bias. This study highlights the need for randomized trials incorporating physiological markers of safe transition to help identify patients that could benefit.
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- Is residual diuresis a reliable proxy of creatinine clearance for titrating the proper beta-lactam dosing regimen in septic critical OLT recipients undergoing CRRT? [Letter]J Crit Care. 2026 Jul 06; 95:155674. [Online ahead of print]JC
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- Authors reply: "VExUS-ED: Early venous congestion is associated with clinical fluid overload in patients with sepsis". [Letter]J Crit Care. 2026 Jul 06; 95:155677. [Online ahead of print]JC
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- Greening critical care by harnessing the planetary impact of medications: What fellows need to know. [Review]J Crit Care. 2026 Jul 01; 95:155672. [Online ahead of print]JC
- Care of critically ill patients involves large amounts of medication, perhaps more than any other aspect of the healthcare system. This has substantial environmental impacts. This manuscript describes how the environmental impacts of medications arise along their lifecycle, how to assess those impacts, and opportunities to reduce medication environmental impact across the critical care and caring…
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- High-dose corticosteroids are associated with higher mortality in patients with COVID-19 ARDS: Results from a nationwide observational study. [Journal Article]J Crit Care. 2026 Jul 01; 95:155670. [Online ahead of print]JC
- CONCLUSIONS: In patients with COVID-19 ARDS, high-dose corticosteroids were associated with higher mortality during the first 28 days after ICU admission.
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- Community-acquired pneumonia outcome is strongly influenced by early arterial pH. [Letter]J Crit Care. 2026 Jun 30; 95:155671. [Online ahead of print]JC
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- Measuring attitudes toward death and dying among adult intensive care unit staff: A systematic review of assessment tools. [Review]J Crit Care. 2026 Jun 30; 95:155659. [Online ahead of print]JC
- CONCLUSIONS: Current instruments provide fragmented and conceptually divergent assessments of ICU clinicians' attitudes toward death and dying. Limited cross-cultural validation and poor evidence of responsiveness constrain their usefulness for evaluating interventions or supporting improvement. More coherent, implementation-ready measurement tools are needed to strengthen end-of-life culture in intensive care.
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- Identifying subgroups of ICU patients with high mortality rates using machine learning: A nationwide, population-based study. [Journal Article]J Crit Care. 2026 Jun 27; 95:155669. [Online ahead of print]JC
- CONCLUSIONS: Interpretable machine learning can identify ICU patient subgroups with ≥80% 6-month mortality using routinely collected data. These groups are predominantly marked by impaired consciousness and reduced urine output. Future work should integrate these insights into ethical, patient-centered frameworks that support appropriate care.
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- Balanced crystalloids versus saline and mortality in hospitalized patients: a hierarchical Bayesian meta-analysis of cluster-randomized trials. [Journal Article]J Crit Care. 2026 Jun 26; 95:155665. [Online ahead of print]JC
- CONCLUSIONS: Balanced crystalloid policies were not associated with a clear reduction in mortality or AKI in cluster-randomized evaluations of routine care. Any true effect is likely modest and dependent on exposure and clinical context. The available evidence remains compatible with modest benefit or no meaningful effect and complements patient-level evidence by informing the real-world effectiveness of fluid policies under routine implementation conditions.
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- Effects of a policy intended to reduce vasopressin use in intensive care unit patients with shock. [Letter]J Crit Care. 2026 Jun 24; 95:155667. [Online ahead of print]JC
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- The use of oXiris hemofilter in the initial continuous renal replacement therapy among patients with septic shock: A propensity score matched analysis. [Journal Article]J Crit Care. 2026 Jun 24; 95:155666. [Online ahead of print]JC
- CONCLUSIONS: In this cohort of septic shock patients undergoing CRRT, unadjusted analyses demonstrated potential improvements in hemodynamic stability and organ function following oXiris therapy. Nevertheless, these preliminary signals were not confirmed by competing risk analysis of the primary outcome. Therefore, the clinical impacts of oXiris CRRT observed in the present study must be viewed cautiously, well-designed prospective investigations are warranted to verify its definitive therapeutic value.
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- What every intensivist should know about monitoring respiratory drive and effort. [Review]J Crit Care. 2026 Jun 23; 95:155668. [Online ahead of print]JC
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