- Optimal Timing of GLP-1 Receptor Agonist Initiation in Patients with Obesity Eligible for Metabolic Bariatric Surgery. [Journal Article]Obes Surg. 2026 Jul 18. [Online ahead of print]OS
- CONCLUSIONS: Initiating GLP-1 RA therapy after MBS appears to provide the most favorable balance of survival, cardiometabolic outcomes, and postoperative complications. These findings, particularly those related to mortality, should be interpreted with caution given the observational design and immortal time bias.
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- A Modified POSE 2.0 Double Helix Megaplication Endoscopic Gastroplasty Pattern for Obesity: Initial One-Year Outcomes in Japan. [Journal Article]Obes Surg. 2026 Jul 18. [Online ahead of print]OS
- CONCLUSIONS: This initial Japanese series suggests that modified MEGA within the POSE 2.0 Double Helix platform achieved favorable 1-year weight loss, acceptable safety, and complete suture retention among evaluated patients. Prospective multicenter validation is warranted.
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- Postoperative Changes in Eating Behavior After Sleeve Gastrectomy are Associated With IL-10 Independent of Anthropometric Changes. [Journal Article]Obes Surg. 2026 Jul 18. [Online ahead of print]OS
- CONCLUSIONS: Changes in eating behavior following LSG were accompanied by changes in inflammatory markers, particularly IL-10. These findings suggest that immune and behavioral adaptations may co-occur during postoperative recovery.
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- Effect of Roux-en-Y Gastric Bypass Surgery and Restricted Diet on Endothelial Progenitor Cells in Egyptian Subjects with Morbid Obesity. [Journal Article]
- CONCLUSIONS: RYGB surgery is more effective than diet restriction in reducing oxidative stress, improving antioxidant defense, and restoring EPCs homeostasis. These benefits may reflect reduced vascular stress and improved endothelial function, supporting RYGB surgery as a potent metabolic intervention for morbid obesity.
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- Virtual Preoperative Education in Bariatric Surgery: Patient Acceptance and Travel-Related Carbon Savings. [Journal Article]
- CONCLUSIONS: Given the increasing prevalence of obesity and the critical role of preoperative education in bariatric care, telemedicine represents an effective strategy to meaningfully reduce travel-related emissions. Virtual educational interventions eliminate CO2-intensive journeys while maintaining broad accessibility and high patient satisfaction. Integrating telemedicine into obesity surgery care pathways can thus significantly contribute to sustainable, climate-conscious healthcare delivery.
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- Bariatric Surgery as a Bridge to Kidney Transplantation in Patients with Obesity and Advanced Chronic Kidney Disease or End-Stage Renal Disease: A Systematic Review. [Review]
- CONCLUSIONS: BS in patients with advanced CKD or ESRD is associated with meaningful weight loss, improvement of obesity-related comorbidities, and acceptable safety, and a majority of patients achieve formal transplant listing or undergo KTx during medium-term follow-up. The evidence base remains dominated by small, single-centre retrospective cohorts with heterogeneous outcome definitions; pooled effect estimates are not currently justified. Larger multicentre studies with standardised outcome reporting are needed.
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- Declining Bariatric Surgery Volumes and Shifting Practice Patterns: A Five-Year Analysis of Over One Million Procedures. [Journal Article]
- CONCLUSIONS: Bariatric surgery volumes declined substantially to pandemic levels while patient complexity increased. Conversion procedures now constitute over 11% of all cases. Improving outcomes despite rising complexity reflect quality improvements at accredited centers. Volume decline threatens training capacity and surgical access for the growing obesity epidemic.
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- Enhancing Postoperative Outcomes After Metabolic Bariatric Surgery: a Pilot Study of Inhibitory Control Training, Transcranial Direct Current Stimulation and Psychosocial Aftercare. [Journal Article]
- CONCLUSIONS: Potential effects may have been attenuated through the small, highly motivated, treatment-seeking sample and the rapidly evolving early postoperative phase. Future fully powered trials should include neurobiological outcome measures that may capture tDCS-induced neural changes earlier and extend FU intervals to clarify efficacy and optimize postbariatric stimulation protocols. Incorporating dismantling designs would further help to disentangle the specific contributions of tDCS, the inhibitory control training and psychosocial care.
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- Prevalence of Psychotropic Drug Treatment Interventions in Patients Undergoing Metabolic and Bariatric Surgery: A Retrospective Study. [Journal Article]
- CONCLUSIONS: Although only a minority of patients required psychotropic drug treatment interventions, monitoring psychotropic drug treatment is essential for safe and effective treatment post-MBS. Greater attention is needed regarding altered drug exposure, and plasma concentration monitoring may help optimize psychotropic pharmacotherapy in these patients.
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- Explainable Machine-Learning Model for Predicting Severe Obstructive Sleep Apnea in Patients Undergoing Metabolic Bariatric Surgery. [Journal Article]
- CONCLUSIONS: The explainable random forest model demonstrated excellent predictive performance and clinical applicability for identifying SOSA in patients undergoing metabolic bariatric surgery. This model may facilitate perioperative risk stratification, targeted monitoring, and individualized clinical decision-making.
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- Optimal Timing for Initiating Liraglutide 3.0 mg in Patients With Persistent Obesity Six Months After Metabolic and Bariatric Surgery. [Journal Article]
- CONCLUSIONS: Early liraglutide initiation, particularly at six months post-surgery, was linked to greater weight loss and more favourable metabolic profiles compared with standard care. These findings suggest that timely pharmacotherapy may be associated with improved long-term weight management outcomes, though causality remains to be established.
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- Differential Biventricular Strain Recovery With Selective Fibrosis Biomarker Regression After Sleeve Gastrectomy: A Prospective CMR Feature-Tracking Study. [Journal Article]
- CONCLUSIONS: Cardiac reverse remodeling after LSG is measurable but uneven within the first year. LV longitudinal mechanics improved alongside mass regression, whereas RVEF rose without parallel longitudinal change, consistent with afterload reduction rather than intrinsic RV recovery. Fibrosis-linked galectin-3 and endotrophin declined while adipokines remained static, indicating distinct fibrotic and adipokine timelines. The components that respond earliest are those that conventional preoperative assessment overlooks.
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- Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass for Obese Kidney Transplant Candidates: A Systematic Review, Meta-Analysis, and Development of a Transplant-Specific Decision Framework. [Review]
- Obesity remains a major barrier to kidney transplantation and is associated with inferior transplant outcomes. We conducted a PRISMA 2020-compliant systematic review and meta-analysis comparing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) in kidney transplant candidates and recipients. PubMed/MEDLINE, Embase, Scopus, and Cochrane CENTRAL were searched through January 2026. Eleven o…
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- First Case Series on Ambulatorial Endoscopic Sleeve Gastroplasty for Morbidity Obesity: A Single Center Experience. [Journal Article]
- CONCLUSIONS: Ambulatory ESG is a safe, effective, and efficient option for selected patients, with a low rate of post-procedure hospitalization, representing a promising approach in bariatric endoscopy.
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- Short-Term Clinical and Metabolic Outcomes of Laparoscopic Sleeve Gastrectomy in Korean Adolescents with Severe Obesity: A Retrospective Analysis. [Journal Article]
- CONCLUSIONS: LSG demonstrated favorable safe and feasible intervention for Korean adolescents with severe obesity within this cohort, achieving significant weight loss and rapid improvements in metabolic and hepatic parameters within the first postoperative year.
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