(Otolaryngology Head and Neck Surgery[TA])
14,887 results
  • Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment. [Journal Article]
    Otolaryngol Head Neck Surg. 2026 Jul 18. [Online ahead of print]Selvasingh JA, Shinn JROH
  • The FDA approval of Otarmeni, an AAV-based gene therapy for biallelic OTOF-associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implantation, which circumvents damaged sensory structures, OTOF gene replacement targets a synaptic deficit in a structurally intact cochlea. Early clinical trial d…
  • Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral. [Journal Article]
    Otolaryngol Head Neck Surg. 2026 Jul 13. [Online ahead of print]Yaniv D, Vainer I, … Bachar GOH
  • CONCLUSIONS: A simple triage algorithm based on age, shortness of breath, uvular edema, prior episodes, and lip swelling may safely guide the need for nasopharyngoscopy in patients with angioedema. Temporal validation confirmed that the approach can markedly reduce unnecessary ENT consultations without compromising airway safety.
  • Toward a Functional Terminology: Reconsidering "Minor Laryngeal Clefts" as Interarytenoid Dysfunction. [Journal Article]
    Otolaryngol Head Neck Surg. 2026 Jul 13. [Online ahead of print]Smith C, Bauman NM, … Preciado DAOH
  • Much confusion surrounds the terminology used to describe minor laryngeal clefts in pediatric otolaryngology. The widely accepted Benjamin-Inglis classification defined type 1 clefts as those where the interarytenoid mucosal is at the level of the vocal folds. However, many children with aspiration and intact supraglottic mucosa respond favorably to interarytenoid augmentation. This finding has p…
  • Head and Neck Free Flap Reconstruction: Current Landscape and Emerging Technologies. [Journal Article]
    Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]Hack S, Remer E, … Karni RJOH
  • CONCLUSIONS: Contemporary head and neck free flap reconstruction has evolved toward a more integrated, systems-oriented model that extends beyond technical reliability. ERAS pathways, frailty-informed assessment, refined intraoperative physiology, and contemporary salvage strategies have informed perioperative management in complex patient populations. Digital planning and emerging computational tools have improved precision and workflow efficiency in selected settings, although many applications remain investigational. Functional outcomes have also gained prominence as important measures of reconstructive success.
  • Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management. [Review]
    Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]Bernier J, Bergeron MOH
  • CONCLUSIONS: Congenital intraoral synechiae demonstrate marked phenotypic heterogeneity and frequent syndromic/multisystem associations. Early multidisciplinary evaluation, proactive airway/feeding planning, and timely surgical release are central to care. However, important gaps remain in the literature, notably the lack of standardized reporting and long-term outcome data.