- Margin Status and Local Recurrence in Early-Stage Oral-Cavity Squamous Cell Carcinoma: Analysis of Reresection Outcomes. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 23. [Online ahead of print]OH
- CONCLUSIONS: RRN margins should not be considered oncologically equivalent to initial negative margins, as demonstrated by higher 3-year LR rates.
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- Barriers to Timely Infant Hearing Loss Diagnosis Utilizing Auditory Brainstem Response. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 20. [Online ahead of print]OH
- CONCLUSIONS: Primary common barriers impacting appropriate and timely EHDI guidelines: Infant sleep state, coordination with other providers, middle ear dysfunction, distance to facility, and scheduling constraints.
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- Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 18. [Online ahead of print]OH
- The FDA approval of Otarmeni, an AAV-based gene therapy for biallelic OTOF-associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implantation, which circumvents damaged sensory structures, OTOF gene replacement targets a synaptic deficit in a structurally intact cochlea. Early clinical trial d…
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- Implementation of a Nebulized Tranexamic Acid Protocol for Pediatric Post-Tonsillectomy Hemorrhage: A Quality Improvement Initiative. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 17. [Online ahead of print]OH
- CONCLUSIONS: Across 2 PDSA cycles, we achieved a 65.4% reduction in the need for surgical control of bleeding for PTH without an increase in balancing measures, used as surrogates for unintended consequences of the interventions.Implementation of a nebulized TXA protocol may be a safe and effective management option for PTH.
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- Characterizing Music Engagement and Reward in Individuals Across a Spectrum of Hearing Loss and Rehabilitation. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 16. [Online ahead of print]OH
- CONCLUSIONS: Poorer hearing status was associated with reduced music perception but not engagement or reward, even among CI users. Non-perceptual factors like musical training and age may play a stronger role in explaining individual differences, highlighting the role of modifiable behavioral factors in enhancing music reward for individuals with HL.
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- Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 13. [Online ahead of print]OH
- CONCLUSIONS: A simple triage algorithm based on age, shortness of breath, uvular edema, prior episodes, and lip swelling may safely guide the need for nasopharyngoscopy in patients with angioedema. Temporal validation confirmed that the approach can markedly reduce unnecessary ENT consultations without compromising airway safety.
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- Toward a Functional Terminology: Reconsidering "Minor Laryngeal Clefts" as Interarytenoid Dysfunction. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 13. [Online ahead of print]OH
- Much confusion surrounds the terminology used to describe minor laryngeal clefts in pediatric otolaryngology. The widely accepted Benjamin-Inglis classification defined type 1 clefts as those where the interarytenoid mucosal is at the level of the vocal folds. However, many children with aspiration and intact supraglottic mucosa respond favorably to interarytenoid augmentation. This finding has p…
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- Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 10. [Online ahead of print]OH
- CONCLUSIONS: The POINT classifier is predictive of genomic alterations and ATA risk in independent data sets. This study advances precision oncology, shifting the paradigm from size-based toward individualized, biology-driven care.
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- Real-Time Light-Guided Vocal Fold Injection for Unilateral Vocal Fold Paralysis: Experience From 378 Consecutive Cases. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 07. [Online ahead of print]OH
- CONCLUSIONS: RL-VFI with HA is a feasible and safe technique for treating patients with UVFP. It enables precise confirmation of needle tip localization and facilitates accurate injection into the intended target during the CT approach.
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- Preoperatively Diagnosed Versus Undiagnosed Major Salivary Gland Cancer: Clinicopathological Characteristics, Treatment Strategies, and Oncological Outcomes. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]OH
- CONCLUSIONS: Preoperatively undiagnosed MSGCs exhibit distinct clinicopathological characteristics, treatment strategies, and oncological outcomes compared to preoperatively diagnosed cases, highlighting the critical role of preoperative diagnosis in the management MSGCs.
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- Estimating Performance Using Tonotopic Measurements of Intracochlear Electrocochleography: Comparison of Lateral Wall and Perimodiolar Arrays. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]OH
- CONCLUSIONS: MA-ECochG-TR independently estimates performance for perimodiolar arrays. Intracochlear ECochG is less predictive for lateral wall arrays; this may be due to confounding from EAS (though this was not statistically significant) or from signal degradation with a larger electrode-modiolar distance.
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- Head and Neck Free Flap Reconstruction: Current Landscape and Emerging Technologies. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]OH
- CONCLUSIONS: Contemporary head and neck free flap reconstruction has evolved toward a more integrated, systems-oriented model that extends beyond technical reliability. ERAS pathways, frailty-informed assessment, refined intraoperative physiology, and contemporary salvage strategies have informed perioperative management in complex patient populations. Digital planning and emerging computational tools have improved precision and workflow efficiency in selected settings, although many applications remain investigational. Functional outcomes have also gained prominence as important measures of reconstructive success.
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- GLP-1 Receptor Agonist Effect on Disease Severity in Idiopathic Subglottic Stenosis. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]OH
- CONCLUSIONS: GLP-1RA therapy increases SFI in iSGS independent of initial BMI or weight loss.
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- Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management. [Review]Otolaryngol Head Neck Surg. 2026 Jul 06. [Online ahead of print]OH
- CONCLUSIONS: Congenital intraoral synechiae demonstrate marked phenotypic heterogeneity and frequent syndromic/multisystem associations. Early multidisciplinary evaluation, proactive airway/feeding planning, and timely surgical release are central to care. However, important gaps remain in the literature, notably the lack of standardized reporting and long-term outcome data.
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- Otovent Versus Valsalva: Physiological Insights for Diagnostic and Therapeutic Autoinflation in Eustachian Tube Dysfunction. [Journal Article]Otolaryngol Head Neck Surg. 2026 Jul 03. [Online ahead of print]OH
- CONCLUSIONS: Otovent facilitates autoinflation at lower but significantly more consistent pressures than Valsalva. Thus, Otovent may offer greater clinical value when a controlled, repeatable insufflation pressure is required for diagnostic or therapeutic purposes.
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