(PLoS Medicine[TA])
5,361 results
  • Expanding the Developmental Origins of Health and Disease beyond maternal behaviors. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005208.Lee AR, Hawcutt DB, … Sinha IPPM
  • Developmental Origins of Health and Disease (DOHaD) research has long emphasized maternal pregnancy behaviors as key determinants of child health. New evidence recently published in PLOS Medicine suggests the greatest opportunities to improve child health may lie in tackling socioeconomic disadvantage rather than maternal behavior alone.
  • Maternal congenital heart disease: Implications for the next generation. [Review]
    PLoS Med. 2026 Jul; 23(7):e1005191.Leirgul E, Greve GPM
  • Advances in medical and surgical treatment of congenital heart disease (CHD) now allows most affected individuals to reach adulthood and parenthood. While maternal CHD is associated with pregnancy complications, emerging evidence suggests a possible increased risk of developmental challenges in offspring, particularly among children of mothers with severe CHD.
  • The cancer survivorship paradox in the digital era. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005174.Hegarty J, Toygar I, … Pawlowska EPM
  • Many assumptions around patient needs and support guide current oncology practice and cancer survivorship care in the digital era. Addressing these assumptions and providing smarter, holistic, tech-enabled follow-up models are essential for truly effective and sustainable person-centered care.
  • Exploring parental prenatal influences on child health: A multicohort study and data visualisation tool. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005153.Sharp GC, Lawlor DA, … Relton CLPM
  • CONCLUSIONS: Our findings suggest that wider familial socioeconomic conditions may be a more important determinant of child health than specific parental health behaviours prenatally. Interventions to improve population health may be most effective if they target wider social inequalities, rather than individual behaviours and mothers specifically. We encourage researchers to use EPoCH Explorer to prioritise associations for exploration in their own datasets, thus enabling replication and cross-context comparison to validate and extend the generalisability of our findings.
  • Whose fears count? Legitimacy, trust and viral outbreak responses after COVID-19. [Editorial]
    PLoS Med. 2026 Jul; 23(7):e1005184.Grais RFPM
  • COVID-19 transformed viral outbreak response from a predominantly public health challenge into a political and security concern. Recent responses to Ebola, mpox, and other emerging infections suggest that preparedness is increasingly shaped by whose fears are prioritized in decision-making. The challenge is ensuring that competing perceptions of risk are managed in ways that are perceived as legi…
  • Brain aging patterns among nine neurological disorders: A case-control study. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1004860.Liang C, Pearlson G, … Calhoun VDPM
  • CONCLUSIONS: In summary, the different brain aging patterns, each based around specific underlying circuits, may serve as neuroimaging biomarkers for understanding the neural aging mechanisms in commonly occurring brain disorders. Future studies should test whether these disorder-specific brain aging patterns can serve as useful biomarkers to guide critical clinical decision-making.
  • Assessing spatial transmission risk of respiratory infectious diseases across cities of different socioeconomic tiers in China: A modelling study. [Journal Article]
    PLoS Med. 2026 Jul; 23(7):e1005172.Li W, Yang W, … Yao YPM
  • CONCLUSIONS: Spatial transmission risk reflects an interaction between pathogen-specific transmissibility and the hierarchical organisation of China's urban mobility system. These findings indicate that surveillance and response strategies effective for less transmissible pathogens may be insufficient for highly transmissible variants. Mobility-informed, tier-specific risk assessment may help inform early warning and support more adaptive public health responses. Because the framework relies on routinely available mobility data and minimal pathogen-specific inputs, it may provide a scalable approach for epidemic preparedness, including potential future emerging respiratory threats (Disease X).
  • Progress and promise of CAR-T cell treatment in autoimmune diseases. [Review]
    PLoS Med. 2026 Jul; 23(7):e1005179.Bachl J, Hagen M, Schett GPM
  • Chimeric antigen receptor (CAR)-expressing cells bear a great potential for the treatment of autoimmune diseases. While numerous challenges persist, recent technological developments have demonstrated the potential for CAR cells to reset dysfunctional immune systems and transform care for patients with autoimmune disease.