Although lumbopelvic disorders are common during pregnancy, evidence regarding their impact on health-related quality of life (HRQoL) remains limited. This study therefore aimed to assess the associations between urinary incontinence, fecal incontinence, constipation, sexual dysfunction, low back pain, and HRQoL during pregnancy. Analysis of covariance (ANCOVA) models and multivariate linear regression analyses were used to examine the associations between these conditions and HRQoL among 375 pregnant women in Nicaragua. Pregnant women with these disorders had significantly poorer HRQoL than those without them. The physical component score was associated with urinary incontinence (β = -0.22, 95 percent CI: -0.42 to -0.01), constipation (β = -0.43, 95 percent CI: -0.64 to -0.21), sexual dysfunction (β = -0.13, 95 percent CI: -0.24 to -0.02) and low back pain (β = -0.75, 95 percent CI: -1.07 to -0.44). The mental component score was associated with constipation (β = -0.41, 95 percent CI: -0.61 to -0.21 and sexual dysfunction (β = -0.13, 95 percent CI: -0.23 to -0.02). In conclusion, this study suggests that urinary incontinence, constipation, sexual dysfunction, and low back pain may be associated with poor physical well-being during pregnancy. Constipation and sexual dysfunction may also be associated with poor mental HRQoL.

TERPT and LA-TERPT are widely used minimally invasive procedures for HD treatment. However, the comparative superiority of either technique in terms of postoperative complications and long-term functional outcomes remains uncertain. An SRMA was conducted in accordance with PRISMA 2020 guidelines and prospectively registered in PROSPERO (CRD420261378340). PubMed/MEDLINE, Embase, Scopus, Web of Science, Google Scholar, and trial registries were searched from inception to May 3, 2026. Comparative studies evaluating TERPT and LA-TERPT in children with HD were included. The primary outcomes were constipation, soiling, fecal incontinence, BFS, HAEC, anastomotic stricture, and anastomotic leak. Secondary outcomes included operative time and hospital stay. A random-effects meta-analysis was performed using log risk ratios (RRs) or mean differences (MDs) with 95% confidence intervals (CIs). Twenty-three studies involving 1,668 children with HD were included, comprising 980 TERPT and 688 LA-TERPT procedures. No significant differences were observed between TERPT and LA-TERPT for constipation (log RR = 0.11), soiling (log RR = 0.05), fecal incontinence (log RR = 0.05), HAEC (log RR = 0.09), BFS > 17 (log RR = - 0.08), anastomotic stricture (log RR = 0.28), or anastomotic leak (log RR = 0.06). TERPT was associated with a significantly shorter operative time (MD = -43.25 min). Post-op hospital stay was comparable between groups (MD = 0.20 days). Most outcomes showed low heterogeneity, whereas operative time and hospital stay showed substantial heterogeneity. This SRMA found no clear evidence that either TERPT or LA-TERPT yields superior postoperative or functional outcomes in children with RSHD. However, the available evidence is largely observational and has low to moderate certainty, so it should be interpreted cautiously. Until higher-quality evidence becomes available, the choice of surgical approach should be guided by disease characteristics, technical considerations, and surgeon expertise.

This study aims to explore the impact of a multidisciplinary dynamic nursing strategy constructed based on the concept of predictive nursing on the incidence, severity, healing status and nursing quality of incontinence-associated dermatitis (IAD) in Intensive Care Unit (ICU) patients and provide a scientific basis for the clinical prevention and control of IAD. A retrospective cohort study design was adopted, selecting 300 patients admitted to the ICU of a tertiary Grade A hospital between January 2023 and December 2024. Based on the time point when the hospital implemented the "Multidisciplinary Dynamic Nursing Strategy Based on Predictive Nursing" starting January 2024, patients were divided into a control group (n = 132, receiving routine care before implementation) and an intervention group (n = 168, receiving multidisciplinary dynamic care after implementation). The control group followed the routine IAD prevention protocol; the intervention group additionally implemented predictive risk assessment, multidisciplinary collaborative intervention, informational nursing support, and quality monitoring. The incidence, severity, healing status of IAD, ICU length of stay, nursing compliance, and quality indicators were compared between the 2 groups. There was no statistically significant difference in the general data between the 2 groups (P > .05), indicating comparability. The incidence of IAD in the intervention group was significantly lower than that in the control group (14.3% vs 28.8%, χ2 = 8.45, P = .004); the severity of IAD was milder in the intervention group (Mild: 75.0% vs 57.9%, P = .022). The complete healing rate of IAD was significantly higher in the intervention group (91.7% vs 65.8%, P = .016), the healing time was significantly shorter (7.2 ± 2.9 days vs 9.7 ± 3.6 days, P < .001), and the ICU length of stay was shorter (13.1 ± 4.9 days vs 15.4 ± 5.8 days, P = .043). Nursing compliance and quality indicators in the intervention group were superior to those in the control group, including daily risk assessment compliance rate, timely warning response rate, nursing record completeness rate, and operational consistency (all P < .01). The multidisciplinary dynamic nursing strategy based on the concept of predictive nursing can effectively reduce the incidence and severity of IAD in ICU patients, promote skin healing, shorten the length of stay, and significantly improve nursing compliance and quality.

Maternal expulsive force is a key determinant of fetal head descent during the active second stage of labour. Pushing is most effective when abdominal muscle contraction is synchronised with relaxation of the levator ani muscle, thereby widening the pelvic hiatus. Trans-perineal ultrasound studies show that 15-20% of nulliparous women paradoxically contract the levator ani (co-activation) during pushing, narrowing the hiatus and slowing head descent. Consequently, about 20% of primigravidas experience a prolonged second stage, with higher rates of operative birth and perineal trauma.

Low anterior resection syndrome (LARS), a prevalent sequela following rectal cancer surgery, poses a substantial burden on patients' quality of life (QOL), daily functioning, and psychological well-being, and its management remains an unmet clinical need due to the absence of specific therapeutic agents. Although traditional Chinese medicine (TCM) shows promise in supporting postoperative gastrointestinal recovery, high-quality evidence for its application in LARS is lacking. This trial is designed to assess the efficacy and safety of the investigational TCM formulation BL-1 in patients with LARS.

Gurltia paralysans is an angio-neurotropic metastrongyloid nematode and the etiologic agent of feline gurltiosis, a rare but emerging parasitic disease in domestic and wild felids. Infection by G. paralysans leads to progressive neurological deficits including ataxia, paraparesis, and fecal/urinary incontinence. This report describes the first confirmed case of feline gurltiosis in Santa Catarina, Brazil, expanding the known geographic distribution of the disease. A 2-years-old domestic cat presented with a six-month history of progressive pelvic limb paralysis and was euthanized due to poor prognosis. Necropsy and histopathology revealed typical lesions of G. paralysans infection in spinal cord samples, such as dilated veins containing metastrongyloid nematodes, thrombosis, and Wallerian degeneration. The G. paralysans DNA was detected by semi-nested PCR for the gene 28S rRNA in a paraffin-embedded spinal cord sample. This case underscores the need for heightened clinical suspicion of gurltiosis in cats with chronic myelopathies, particularly in rural areas of South America.