- Central venous-arterial CO2 gap to arterial-central venous O2 content difference ratio in guiding of fluid resuscitation of patients with septic shock. [Journal Article]Medicine (Baltimore). 2026 May 08; 105(19):e48666.M
- CONCLUSIONS: Pv-aCO2/Ca-vO2 may serve as a reliable parameter for determining the fluid resuscitation target in patients with septic shock.
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- Clinical outcomes after deep enteroscopy in patients with obscure gastrointestinal bleeding: a single-center retrospective study. [Journal Article]BMC Gastroenterol. 2026 May 11. [Online ahead of print]BG
- CONCLUSIONS: Patients requiring therapeutic DBE appear to represent a higher-risk population with more severe baseline anemia and ongoing transfusion needs. These findings suggest that combined endoscopic management and adjunctive medical therapy may be necessary in complex small-bowel bleeding. Prospective studies are needed to clarify the impact of DBE-directed therapy on long-term clinical outcomes.
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- Clinical outcomes of transcatheter arterial embolization in patients with angiography-negative duodenal ulcer bleeding after failed endoscopic hemostasis. [Journal Article]BMC Gastroenterol. 2026 May 11. [Online ahead of print]BG
- CONCLUSIONS: For patients with angiography-negative duodenal ulcer bleeding after failed endoscopic hemostasis, TAE appears to be a feasible and safe salvage option. These preliminary findings suggest that empiric embolization may achieve effective bleeding control even in the absence of definite angiographic evidence of active bleeding. An exploratory subgroup analysis suggested that the choice of embolic material may influence early hemostatic outcomes, warranting further prospective investigation.
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- Retrospective Cohort Study on the Efficacy and Safety of Endoscopic Submucosal Dissection for Gastrointestinal Lesions: A Single-Center Experience. [Journal Article]Middle East J Dig Dis. 2025 Oct; 17(4):253-260.ME
- CONCLUSIONS: ESD is a safe and effective technique for the complete en bloc resection of GI lesions, with high success rates and low recurrence. En bloc resection is superior to piecemeal resection, particularly for larger lesions. While complications such as perforation and bleeding are rare, they can be managed endoscopically. These findings support the use of ESD as a viable alternative to surgery, especially for elderly patients or those with surgical contraindications. Further multicenter studies with long-term follow-up are needed to validate these results and optimize ESD techniques globally.
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- P-CAB vs. PPI for Upper Gastrointestinal Bleeding Prevention in Patients With Atherothrombotic Disease on Antithrombotic Therapy: A CDM Cohort Study. [Journal Article]Aliment Pharmacol Ther. 2026 May 09. [Online ahead of print]AP
- CONCLUSIONS: In patients receiving antithrombotic therapy, P-CABs are associated with a significantly lower risk of clinically significant GI bleeding compared to PPIs. These findings support P-CABs as a potent acid-suppressive strategy for gastroprotection in high-risk populations.
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- Safety and efficacy of Enhanced Recovery after Surgery (ERAS) in pancreaticoduodenectomy combined with vascular reconstruction. [Journal Article]Surg Oncol. 2026 May 05; 66:102445. [Online ahead of print]SO
- CONCLUSIONS: Implementation of the ERAS protocol in PD with vascular reconstruction is safe and feasible, showing preliminary evidence in mitigating surgical stress and accelerating hepatic and gastrointestinal functional recovery. The ERAS cohort experienced a significant reduction in DGE and shorter hospital stays without increasing postoperative complications. These findings support ERAS as a standardized perioperative framework even for PD with vascular reconstruction.
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- Association of endoscopic intervention with mortality in gastrointestinal bleeding after open-heart surgery: a propensity-score cohort study. [Journal Article]Front Med (Lausanne). 2026; 13:1713252.FM
- Postoperative gastrointestinal bleeding (GIB) after open-heart surgery is associated with increased mortality, yet the prognostic impact of endoscopic intervention remains uncertain.
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- Variations in symptoms, endoscopy use and emergency diagnosis of colorectal cancer by body mass index: a retrospective cohort study using linked electronic health records in England. [Journal Article]BMJ Open. 2026 May 07; 16(5):e107468.BO
- CONCLUSIONS: Patients with CRC with higher BMI are more likely to be referred urgently and less likely to experience emergency cancer diagnosis than normal weight patients.
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- Technical and Medical Challenges in the Mountain Rescue of a Fatally Injured BASE Jumper: A Case Report. [Journal Article]Wilderness Environ Med. 2026 May 07; :10806032261446176. [Online ahead of print]WE
- BASE jumping accidents at Kjerag, a 984-m vertical cliff in Norway, occur on an annual basis and can necessitate complex rescue operations involving coordinated efforts between helicopters and alpine rescue teams. Each operation poses distinct logistical, technical, and medical challenges. This case report aims to contribute to collective learning and continuous quality improvement in the managem…
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- Medical Complications After Mechanical Thrombectomy: Analysis of Trends in US Admissions From 2010 to 2022. [Journal Article]Stroke Vasc Interv Neurol. 2026 May; 6(3):e002147.SV
- CONCLUSIONS: The prevalence of pneumonia and UTI declined, whereas acute renal failure prevalence more than doubled in acute ischemic stroke MT hospitalizations over the last decade. Complications were consistently linked to poorer discharge outcomes and higher in-hospital mortality, underscoring the need for targeted prevention strategies to optimize postthrombectomy care.
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- Early administration of low molecular weight heparin in hypertriglyceridemia-induced acute pancreatitis: A propensity score-matched retrospective cohort study. [Journal Article]J Clin Lipidol. 2026 Apr 14. [Online ahead of print]JC
- CONCLUSIONS: Early application of LMWH was associated with a significant reduction in mortality and organ failure risk in patients with HTG-AP without increasing bleeding complications. Patients with severe disease, diabetes, or high inflammatory burden may derive greater benefit, but further mechanistic studies are needed to guide patient selection.
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- Effectiveness and safety of mirikizumab in ulcerative colitis: real-world data from the Latium Net. [Multicenter Study]BMJ Open Gastroenterol. 2026 May 05; 13(1).BO
- CONCLUSIONS: Mirikizumab demonstrated meaningful clinical effectiveness and a favourable safety profile in a real-world setting, including in biologic-experienced patients.
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- Protective Impact of GLP-1 Therapy on Post-ERCP Outcomes: A TriNetX Retrospective Cohort Analysis. [Journal Article]J Clin Gastroenterol. 2026 May 05. [Online ahead of print]JC
- CONCLUSIONS: In this large real-world analysis, preprocedure GLP-1 RA therapy was associated with markedly reduced 30-day ERCP-related adverse events, most notably PEP. These findings highlight a potential protective role of GLP-1 signaling in the periprocedural inflammatory response and support prospective studies evaluating GLP-1 RAs as adjunctive prophylactic agents in ERCP. Further prospective studies are needed.
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- Massive lower gastrointestinal bleeding of unusual origin: splenic artery pseudoaneurysm in necrotizing pancreatitis. [Journal Article]Gastroenterol Hepatol. 2026 May 02; :502773. [Online ahead of print]GH
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- Global complications among patients with mpox: a systematic review and meta-analysis. [Journal Article]EClinicalMedicine. 2026 May; 95:103911.E
- Despite increasing global attention, significant knowledge gaps remain regarding the incidence of adverse outcomes associated with mpox. To support the development of World Health Organization (WHO) mpox guidelines, this systematic review and meta-analysis evaluated the incidence of complications among patients with mpox.
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