This study reports a rare case of femoroacetabular impingement (FAI) combined with massive acetabular labrum calcification. The patient was a 48-year-old female sports enthusiast who had experienced right hip pain for over six months. Despite conservative treatment aimed at reducing swelling and alleviating pain, she still suffered from hip pain and restricted movement. She underwent right hip arthroscopy under general anesthesia, including removal of the calcified lesion of the acetabular labrum, reconstruction of the labrum with autologous gracilis tendon, and femoral head-neck reshaping. At the nine-month follow-up, the patient's hip function had improved significantly, with no complications such as nerve or vascular injury, wound infection, or heterotopic ossification. This case suggests that hip arthroscopy with labral reconstruction may represent a viable treatment option that may contribute to improved symptoms and function in patients with FAI combined with large labral calcifications; it may facilitate return to sports and enhance quality of life, potentially offering a therapeutic strategy for the clinical management of such conditions.

Hip preservation surgery (HPS) is increasingly performed in young and active patients with the aim of delaying or avoiding total hip arthroplasty (THA). Despite advances in preservation techniques, a proportion of patients eventually progress to end-stage hip disease and require conversion to THA. Performing THA after prior HPS presents unique challenges because of altered anatomy, retained hardware, soft-tissue scarring, and compromised bone quality. This narrative review evaluates the existing literature on THA following various hip preservation procedures, including hip arthroscopy, periacetabular osteotomy, femoral osteotomies, and core decompression. A comprehensive review of PubMed-indexed studies was undertaken to assess indications for conversion, preoperative considerations, intraoperative challenges, surgical strategies, and clinical outcomes. Available evidence suggests that conversion THA after HPS is generally more technically demanding than primary THA, often resulting in longer operative times and increased blood loss. Nevertheless, most studies report significant improvements in pain relief, function, and patient satisfaction, with short-to mid-term outcomes comparable to those of primary THA. However, patients with a history of complex reconstructive procedures, particularly femoral or pelvic osteotomies, may experience higher rates of complications and revision surgery. Successful outcomes depend on meticulous preoperative planning, detailed understanding of previous interventions, and appropriate surgical expertise. Although current evidence supports THA as a reliable and effective option following failed HPS, further high-quality, long-term studies are needed to better define outcomes, identify risk factors for complications, and optimize surgical techniques in this challenging patient population.

Introduction: Chronic non-specific low back pain (CNLBP) is associated with altered lumbopelvic mechanics and impaired hip mobility. This study examined whether changes in pain-provoking hip flexion are associated with changes in low back pain and assessed agreement between inertial measurement units (IMUs) and a markerless motion capture system. Methods: Thirty-six patients with CNLBP completed a longitudinal repeated-measures rehabilitation protocol consisting of approximately 13 physiotherapy sessions over a period of up to 6 weeks. Active hip flexion was assessed in the symptomatic limb (the limb provoking lumbar pain). Hip flexion was recorded during the same movement trial using IMUs and a markerless system. Pain and disability were assessed using the Visual Analogue Scale and Oswestry Disability Index. Results: Improvements in hip flexion were moderately associated with pain reduction (markerless: r = -0.52; IMU: r = -0.57), with negligible associations with disability. Markerless and IMU measurements showed a strong correlation (r = 0.87), while Bland-Altman analysis showed consistent underestimation by the markerless system (bias = -3.67°). Conclusions: Symptom-specific hip mobility is associated with pain reduction in CNLBP, highlighting the role of lumbopelvic biomechanics. IMUs demonstrated higher consistency, while markerless systems offered a more accessible alternative for clinically meaningful movement assessment.

Background: Intraoperative periprosthetic proximal femoral fractures (PPFFs) represent a significant complication during total hip arthroplasty (THA), especially when using cementless stems via a direct anterior approach (DAA). Methods: This retrospective case series evaluated 10 patients with Vancouver A2 PPFFs treated with 2.7 mm lag screws alone or in combination with plates during DAA THA or partial hip arthroplasty between January 2021 and March 2024. Results: All fractures healed. One patient experienced 1 cm of stem subsidence without the need for revision. The mean Harris Hip Score improved from 35.4 preoperatively to 85.6 postoperatively. Functional recovery and radiological stability were comparable between fixation methods, though the screw-only group experienced slightly more postoperative pain. Patients in the screw-and-plate group were significantly older than those in the screw-only group (p = 0.026). No significant differences were found between groups regarding surgical time (p = 0.62) or BMI (p = 0.82). Due to the limited number of subsidence events, the statistical comparison of subsidence rates was inconclusive. Conclusions: In this preliminary retrospective case series, the use of 2.7 mm lag screws and small locking plates appeared feasible and was associated with favorable short-term outcomes in selected Vancouver A2 intraoperative PPFFs during DAA. These findings are hypothesis-generating and require confirmation in larger, prospective comparative studies.

Background/Objectives: Hip arthroscopy is a minimally invasive procedure with rare complications that can occur due to air entry outside the joint space. Case Presentation: A 19-year-old patient underwent right hip arthroscopy with attempted joint venting. The next morning, she had pain in her right leg, neck, and chest with paresthesias over her hands and feet. A subsequent emergency department physical exam revealed crepitation of the lower extremities, abdomen, chest, and neck caused by air entrance during arthroscopy. The patient also reported blurred near vision. Additionally, the pupils were fixed, did not accommodate, and were dilated at 7 mm. Computed tomography scans revealed subcutaneous emphysema, pneumoperitoneum, pneumomediastinum, and cervicofacial emphysema. Magnetic resonance imaging of the brain revealed a Chiari I malformation. The patient received four hyperbaric oxygen treatments. By the fourth treatment, near visual acuity had improved, but far visual acuity had worsened. Vision had returned to normal eight days after discharge. Conclusions: It is proposed that the patient's reduced near vision, accommodation paralysis, and fixed and dilated pupils were brought about by pneumomediastinum and cervicofacial emphysema, inhibiting the ability of the pupils to constrict, causing bilateral mydriasis and accommodation paralysis for near targets. Additionally, the subsequent transient myopic shift is a known complication of hyperbaric oxygen therapy, which increases the refractive index of the crystalline lens.

Background: Robot-assisted total knee arthroplasty (raTKA) improves the precision of component positioning and coronal alignment restoration, but it remains uncertain whether that technical accuracy modifies the clinical effect of alignment strategy in different varus phenotypes. The present report evaluates alignment strategy and correction magnitude, explicitly as a post hoc exploratory deformity-subgroup analysis within a randomized raTKA cohort. Methods: This single-center, open-label, randomized study enrolled 296 patients with varus knee osteoarthritis who underwent raTKA between 2023 and 2025 using either mechanical alignment (MA; n = 149) or limited/restricted kinematic alignment (lim.-KA; n = 147). The parent randomized comparison was conducted at the whole-cohort level; the deformity-based subgroups reported here were defined after the whole-cohort analysis and are therefore post hoc and exploratory. Patients were stratified according to preoperative varus severity into a mild-deformity subgroup (≤10°; lim.-KA-I n = 99, MA-I n = 102) and a moderate-deformity subgroup (11-20°; lim.-KA-II n = 48, MA-II n = 47). Outcomes included hip-knee-ankle angle (HKA), correction angle, range of motion (ROM), visual analog scale (VAS; 0-10 points), Knee Society Score (KSS; knee and function), Oxford Knee Score (OKS), and Forgotten Joint Score-12 (FJS-12) over 12 months. Estimates are presented with 95% confidence intervals where applicable. Because multiple post hoc subgroup comparisons were performed without formal multiplicity adjustment, p-values are interpreted descriptively and in conjunction with effect sizes and 95% confidence intervals. Results: The primary whole-cohort randomized comparison did not demonstrate an overall between-group advantage of either alignment strategy. The post hoc moderate-varus subgroup showed favorable unadjusted 12-month differences for lim.-KA versus MA in KSS-knee (+6.8 points; 95% CI 5.3 to 8.3; nominal p < 0.001), KSS-function (+4.0 points; 95% CI 2.7 to 5.2; nominal p < 0.001), OKS (+6.4 points; 95% CI 4.5 to 8.3; nominal p < 0.001), and FJS-12 (+11.3 points; 95% CI 9.4 to 13.1; nominal p < 0.001). In contrast, ROM favored MA rather than lim.-KA in the moderate-varus subgroup (-11.8°; 95% CI -16.6 to -7.0; nominal p < 0.001), indicating greater 12-month ROM after MA, and VAS pain, reported on a 0-10 scale, did not support a lim.-KA pain advantage (+0.26 points; 95% CI 0.05 to 0.48; higher scores indicate worse pain; nominal p = 0.018). Exploratory, unadjusted, post hoc 12-month alignment-by-deformity interaction terms were significant for ROM, KSS-knee, KSS-function, OKS, and FJS-12, but not for VAS. Because multiple post hoc comparisons were performed without formal multiplicity adjustment, the results are interpreted descriptively, along with effect sizes and confidence intervals. Conclusions: The primary randomized comparison did not demonstrate a clinical advantage of lim.-KA over MA in the whole cohort. In post hoc exploratory analyses, mild varus deformity was associated with outcomes broadly similar to those after both alignment strategies. In the moderate-varus subgroup, patient-level analyses suggested a possible phenotype-dependent signal for KSS-knee, KSS-function, OKS, and FJS-12 after lim.-KA, whereas ROM favored MA, and VAS pain did not support a lim.-KA pain advantage. These subgroup findings should be interpreted separately from the primary randomized result, considered hypothesis-generating only, and not used in isolation to change clinical practice without prospective confirmation.

Patellofemoral pain (PFP) in athletes is associated with lower-limb kinetic-chain constraints, yet rehabilitation strategies targeting both hip and ankle mobility remain insufficiently examined. This assessor-blinded randomized controlled trial investigated the effects of a 6-week hip and ankle mobility-based rehabilitation program in male collegiate athletes with PFP. Forty-eight participants were assigned using computer-generated 1:1 randomization to an intervention group (n = 24) or a control group (n = 24). The intervention group completed supervised hip and ankle mobility rehabilitation three times weekly, whereas the control group maintained regular sport-specific training only. Co-primary outcomes were pain intensity assessed using a 10-cm visual analog scale (VAS) and knee-related function assessed using the Kujala score. Secondary outcomes included hip rotation range of motion, weight-bearing ankle dorsiflexion, vastus medialis-vastus lateralis (VM-VL) onset timing, Y-Balance Test (YBT) composite score, and countermovement jump (CMJ) height. Significant group × time interactions favored the intervention group for VAS (p < 0.0001; partial η2 = 0.436; change difference: -1.54 cm; 95% CI: -2.06 to -1.02) and Kujala score (p < 0.0001; partial η2 = 0.285; change difference: 8.00 points; 95% CI: 4.24 to 11.76). Significant interactions were also observed for hip internal and external rotation range of motion, weight-bearing ankle dorsiflexion, VM-VL onset timing during a controlled squat task, and YBT composite score (all p ≤ 0.0405; partial η2 = 0.088-0.374). No significant group × time interaction was observed for CMJ height (p = 0.0511; partial η2 = 0.080). These findings suggest that, compared with regular sport-specific training alone, adding a supervised hip and ankle mobility-based rehabilitation program may improve pain, knee-related function, targeted mobility outcomes, VM-VL onset timing during a controlled squat task, and dynamic balance in the short term. However, because the control group did not receive an active or attention-matched intervention, these findings should be interpreted as the added effect of the supervised rehabilitation program rather than as definitive evidence of mobility-specific treatment effects. In addition, because patellar tracking, knee kinematics, joint kinetics, and patellofemoral joint loading were not directly measured, the findings should be interpreted as clinical and functional outcome changes rather than direct evidence of a confirmed biomechanical mechanism. Trial registration: NCT07542236.

Total hip arthroplasty (THA) is among the most effective orthopedic interventions for osteoarthritis, yet post-operative rehabilitation is frequently delayed due to informational and organizational barriers. Geographic information system (GIS) technology offers a promising approach to improving rehabilitation access coordination, though its integration into patient-facing mobile platforms remains insufficiently studied. This two-arm, parallel-group, superiority randomized controlled trial enrolled 142 adult patients (≥18 years) within seven days of primary THA at the National Research Oncology Center LLC, Astana, Kazakhstan. Participants were randomized 1:1 to the GIS-integrated Health-GIS mobile coordination platform (experimental group) or standard general practitioner (GP)-mediated referral (control group). Key exclusion criteria included severe cognitive or visual impairment, absence of smartphone access or digital literacy, and medical contraindications to rehabilitation. The primary outcomes were time to second-stage rehabilitation initiation and health-related quality of life assessed by the SF-12 (Physical and Mental Component Summaries). Secondary outcomes included the Harris Hip Score (HHS), Visual Analogue Scale (VAS) for pain, System Usability Scale (SUS), and quality-adjusted life years (QALYs) over a 12-month follow-up. Of 142 randomized participants (61% male, 39% female), 131 completed follow-up and were included in the modified intention-to-treat analysis (experimental: n = 66; control: n = 65). The experimental group initiated second-stage rehabilitation significantly earlier (median 43 vs. 59 days; p = 0.021). At 12 months, the experimental group demonstrated superior SF-12 Physical Component Summary scores (48.21 vs. 42.84; p < 0.001), while Mental Component Summary scores did not differ significantly between groups (46.96 vs. 47.05; p = 0.669). Quality-adjusted life years were significantly higher in the experimental group (0.74 ± 0.04 vs. 0.72 ± 0.04; p = 0.008). Harris Hip Scores were significantly better in the experimental group at 6 weeks (p < 0.001) and 6 months (p = 0.009), converging by 12 months (p = 0.068). No statistically significant between-group differences in pain intensity (VAS) were observed at any time point (baseline: p = 0.814; 6 weeks: p = 0.336; 6 months: p = 0.066; 12 months: p = 0.105). Platform usability was rated as good-to-excellent by clinicians (SUS: 86.9 at 6 months) and acceptable by patients (mean SUS: 71.4). A GIS-integrated mobile coordination platform significantly reduced time to rehabilitation initiation and improved physical health-related quality of life and health utility following THA compared to standard referral practice. These findings support platform-based care coordination as an effective complement to surgical care, with important implications for rehabilitation access policy. Future multi-center studies and formal cost-effectiveness analyses are warranted to establish generalizability. Trial Registration: ClinicalTrials.gov, NCT07201116, registered 23 September 2025.

Alkaptonuria (AKU) is a rare inherited metabolic disorder characterized by progressive musculoskeletal damage, chronic pain, and functional heterogeneity. To better quantify this variability, we introduced the concept of the functional age gap, defined as the difference between chronological age and a data-derived estimate of functional age. The study included 134 patients with AKU from the ApreciseKUre database. Functional age was calculated by mapping Health Assessment Questionnaire Disability Index (HAQ-DI) and Knee Injury and Osteoarthritis Outcome Score (KOOS) values to age-referenced normative data. Most patients (94.8%) showed a positive functional age gap, with a mean difference of 15 years, which indicates a functionally older profile than expected for their chronological age. A bagging ensemble of decision trees was then used to explore relationships between clinical variables and functional age gap severity. The model achieved moderate but stable classification performance across repeated stratified cross-validation (64%), consistent with an exploratory analysis in a small rare-disease cohort. SHapley Additive exPlanations analysis identified age, AKUSSI spinal pain, AKUSSI joint pain, Schober test, and hip and knee activity as the most influential predictors. These findings support the functional age gap as an interpretable, hypothesis-generating descriptive metric for functional assessment in AKU, while its predictive utility for individual patient stratification will require validation in larger and longitudinal cohorts.

This matters arising article was written in response to the recent article by Chen et al regarding "Effect of perioperative ultrasound guided fascia iliaca compartment block in elderly adults with hip fractures undergoing arthroplasty in spinal anesthesia-a randomized controlled trial", which is published on BMC Geriatrics at February, 2023. The main findings of Chen et al' study are that the fascia iliaca compartment block (FICB) before spinal anesthesia reduces positioning pain, shorten procedure time of spinal anesthesia, prolongs duration of analgesia and improves quality of early postoperative recovery, but reduces postoperative muscle strength. While the efforts of using the existing technique by Chen et al. to optimize patient comfort during spinal anesthesia procedure should be acknowledged, we have noted several issues about methods and results of this study that are not well addressed, such as the lack of detailed perioperative analgesic scheme, clinical significance of reduced positioning pain during spinal anesthesia procedure with the FICB, adverse motor effect of the FICB, time needed for additional FICB, and others. We believe that clarification of these issues is helpful for quality improvement of further randomized clinical trials assessing the benefits of a regional block in elderly patients with hip fractures undergoing arthroplasty under spinal anesthesia.