- Medicine regenerative versus steroids: time to reconsider treatment of chronic inflammatory pain. [Journal Article]Minerva Anestesiol. 2026 May 06. [Online ahead of print]MA
- CONCLUSIONS: For inflammatory-degenerative musculoskeletal and spinal conditions, PRP seems to offer more persistent benefits than CS, while CS is valuable for rapid short-term analgesia. Treatment selection should be guided by phenotype. Standardization of PRP protocols (composition, dose, activation) and high-quality multicentre RCTs are still needed. Conceptualizing PRP as primarily an immuno-inflammatory modulator drug in pain therapy rather than strictly "regenerative" may better explain its longer-term effects.
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- Effect of sagittal alignment on patient outcomes following total knee replacement: A systematic review and correlation analysis. [Review]J Exp Orthop. 2026 Apr; 13:e70731.JE
- CONCLUSIONS: This review provides the first quantitative synthesis linking post-operative sagittal alignment parameters with PROMs. Higher posterior-tibial-slope, femoral flexion, and posterior-condylar offset, and lower femoral-sagittal angle were each significantly associated with improved PROMs, underscoring the importance of sagittal alignment beyond the coronal plane. However, heterogeneity in measurement protocols, underreporting of parameters limit comparability and generalisability. Standardised, multiplanar reporting is essential to help define evidence-based alignment associations and inform surgeons about how best to improve patient outcomes.
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- Rotating-hinge arthroplasty for chronic posterolateral knee fracture-dislocation. [Case Reports]Trauma Case Rep. 2026 Apr; 62:101331.TC
- CONCLUSIONS: Rotating-hinge TKA offers a valuable reconstructive option in chronic knee fracture-dislocations with severe ligament deficiency, providing stable, pain-free, and functional outcomes when anatomic reconstruction is not feasible.
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- Removal of broken solid intramedullary nail of femur: A case report on removal technique in a resource-limited setup. [Case Reports]Trauma Case Rep. 2026 Apr; 62:101344.TC
- CONCLUSIONS: The broken distal end of a solid retrograde nail in a resource-limited setup can be removed by pushing with the tip of another broken nail to the piriformis or from the piriformis to the knee after an entry hole was made in the proximal or distal femur, respectively. Nail removal should be performed with meticulous preoperative planning and preparation of different extraction devices.
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- Intraoperative Liposomal Bupivacaine Is Associated With Reduced Opioid Use and Enhanced Recovery After Total Knee Arthroplasty: A Multicenter Registry Study. [Journal Article]Arthroplast Today. 2026 Jun; 39:101968.AT
- CONCLUSIONS: Use of LB is associated with improved pain control, reduced opioid use, and shorter lengths of stay following TKA. This study highlights LB's utility in facilitating early mobilization and advancing perioperative care.
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- Patient Expectations for Patient-reported Outcomes After Total Knee Arthroplasty Surpass Actual Outcomes and Correlate With Dissatisfaction. [Journal Article]Arthroplast Today. 2026 Jun; 39:101996.AT
- CONCLUSIONS: Patients undergoing TKA commonly expect improvements exceeding both MCIDs and actual postoperative outcomes. Larger expectation-outcome discrepancies were associated with postoperative dissatisfaction, highlighting the importance of aligning patient expectations with realistic outcomes during preoperative counseling.
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- Osteochondral autograft transfer for capitellar osteochondritis dissecans in high-level adolescent athletes. [Journal Article]JSES Int. 2026 May; 10(3):101680.JI
- CONCLUSIONS: Treatment of large, unstable OCD lesions of the capitellum in adolescent athletes is safe, allows for a high rate of return to sport, and has good clinical outcomes with long-term follow-up.
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- [Clinical controlled study of Zhongyi Ointment() in the treatment of Kellgren-Lawrence gradeⅡknee osteoarthritis with moderate-to-severe pain]. [Randomized Controlled Trial]Zhongguo Gu Shang. 2026 Apr 25; 39(4):336-42.ZG
- CONCLUSIONS: Zhongyi Ointment() can rapidly and significantly improve symptoms in patients with K-L gradeⅡknee osteoarthritis with moderate-to-severe pain during the acute exacerbation stage, with definite short-term efficacy and favorable safety. Continuous treatment helps to consolidate the therapeutic effect and warrants further validation through multicenter studies with large sample sizes, as well as investigations into the underlying mechanisms.
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- [Effect of bone-setting manipulation on lower extremity alignment in patients with varus knee osteoarthritis]. [Journal Article]Zhongguo Gu Shang. 2026 Apr 25; 39(4):329-35.ZG
- CONCLUSIONS: Bone-setting manipulation is effective in reducing pain, stiffness, and improving joint function in patients with KOA. The therapeutic mechanism may be due to the correction of the subtle dislocation across the spine, hip, knee, and ankle, thereby reducing bilateral lower limb mechanical axis discrepancies and balancing weight distribution across both knee joints.
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- Association of preoperative corticosteroids with persistent opioid requirements following total knee arthroplasty: an exploratory population-based cohort study. [Journal Article]Can J Anaesth. 2026 May 05. [Online ahead of print]CJ
- CONCLUSIONS: Our exploratory retrospective cohort study suggests that, after accounting for other potential covariates, patients who were previously opioid-naïve and who were exposed to preoperative corticosteroids may have greater odds (or risk given the low incidence) of persistent opioid claims at 3 and 6 months after TKA. This association may have important clinical implications and requires validation through further observational and randomized studies.
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- Dry Needling and Exercise in the Treatment of Musculoskeletal Pain: A Systematic Review. [Journal Article]Sportverletz Sportschaden. 2026 May 05. [Online ahead of print]SS
- Musculoskeletal pain presents a major global public health burden as it is a highly prevalent and disabling health condition. Non-pharmacologic treatments such as therapeutic exercise and dry needling are increasingly utilized in current practice although uncertainty remains regarding their comparative and combined effectiveness. This study aimed to systematically review contemporary evidence reg…
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- Adductor canal block catheters and post-TKA outcomes: Weighing pain management against complication risks. [Journal Article]J Orthop Surg (Hong Kong). 2026 Jan-Apr; 34(2):10225536261449655.JO
- BackgroundAdductor canal block (ACB) catheters are an effective method of pain control for patients undergoing total knee arthroplasty (TKA). Despite their widespread use, there is limited research analyzing their impact on postoperative outcomes. Thus, this study compares 30 and 90 days postoperative outcomes in TKA patients stratified by the use of an ACB catheter.MethodsThis retrospective, pro…
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- Simultaneous Quadriceps Tendon Rupture, Contralateral Patellar Tendon Rupture, and Lateral Meniscus Tear Following a Single Fall: A Case Report. [Case Reports]Cureus. 2026 Apr; 18(4):e106395.C
- Simultaneous ruptures of the quadriceps tendon and contralateral patellar tendon are exceedingly rare, particularly in patients without serious comorbidities or other known predisposing factors. We present the case of an obese 31-year-old man without metabolic syndrome or any other known predisposing risk factors who suffered a right quadriceps tendon rupture and simultaneous left patellar tendon…
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- Radiographic Imaging to improve frontal plane weight bearing symmetry and its impact on gait in transtibial bone anchored prosthesis users. [Journal Article]Sci Rep. 2026 May 04. [Online ahead of print]SR
- Optimal frontal plane alignment of transtibial bone-anchored prostheses (BAPs) is essential to minimize knee joint loading asymmetries. This study examined whether bilateral whole-leg radiographic imaging could improve static alignment and reduce knee joint loading during gait in 23 unilateral transtibial BAP users with press-fit osseointegration implants with an experimental within subject study…
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- What aspects of pain and functional outcomes contribute to patient satisfaction 1 year after surgery within total hip and total knee arthroplasty populations? A registry-based cohort study. [Journal Article]Acta Orthop. 2026 May 05; 97:265-271.AO
- CONCLUSIONS: After THA/TKA, patient satisfaction is associated with pain during basic daily tasks-especially walking and stair climbing. Key functional drivers differ by joint: socks and stairs matter for THA, rising from sitting and getting in/out of a car matter for TKA.
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