- Beyond structural defect: quality of life impact of nasal septal perforation in adults - a scoping review of validated patient-reported outcome measures. [Review]Eur Arch Otorhinolaryngol. 2026 May 05. [Online ahead of print]EA
- CONCLUSIONS: NSP is associated with clinically meaningful QoL impairment, particularly in rhinologic, sleep and psychological domains. Despite growing interest, evidence remains heterogeneous and limited by variable reporting of perforation characteristics and inconsistent use of QoL instruments. Standardized assessment and dedicated NSP-specific outcome measures are needed. Future research should focus on prospective, multicentred studies evaluating both symptom burden and long-term treatment outcomes.
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- Revision Rhinoplasty in Retrocolumellar Perforation. [Journal Article]
- CONCLUSIONS: RCP repair using structured vascularized flaps achieves high closure rates, reliable nasal tip support, and significant functional and cosmetic improvement. Gingivobuccal flaps are particularly valuable in revision cases with compromised anterior support.
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- Poorly functioning right ventricle, pulmonary regurgitation, and atrial septal defect: an unfavorable combination for one-and-one-half ventricle circulation. [Journal Article]
- A newborn infant with pulmonary atresia, intact ventricular septum, and moderately hypoplastic right ventricle underwent radiofrequency perforation and balloon dilation of the pulmonary valve immediately after birth, followed by one-and-one-half ventricle (1.5 V) repair at 5 months of age. At 7 years of age, the patient developed worsening cyanosis and exercise intolerance with increasing right-t…
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- Timing of Nasal Splint Removal After Septoplasty and Its Effects on Postoperative Functional Outcomes and Complications: A Systematic Review and Meta-Analysis. [Review]Cureus. 2026 Mar; 18(3):e105960.C
- The optimal timing for intranasal splint removal following septoplasty remains controversial. This systematic review and meta-analysis assessed how splint removal timing affects postoperative pain, nasal function, olfactory performance, and complications. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we systematically searched PubMe…
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- Multiple ventricular septal defects and severe tricuspid regurgitation in an infant - a case report and surgical dilemma. [Journal Article]J Cardiothorac Surg. 2026 Apr 27. [Online ahead of print]JC
- CONCLUSIONS: Children with severe tricuspid regurgitation, right ventricular failure, Swiss cheese morphology, multiple ventricular septal defects, genetic disorders and low weight may be considered for minimal invasive approaches including perventricular device closure of the ventricular septal defects whenever feasible to avoid operative risks and offer better outcomes.
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- Cocaine-induced ANCA-associated vasculitis: Cohort analysis from a referral center and literature review. [Journal Article]Eur J Intern Med. 2026 Apr 22; :106899. [Online ahead of print]EJ
- CONCLUSIONS: CLAAS is a distinct clinicopathologic entity that overlaps with GPA but differs in histopathology, therapeutic response, and prognosis. Accurate diagnosis requires integrating toxicologic testing and recognizing substance-use patterns.
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- Effectiveness and safety of REVIVENT-TC system for the left ventricular reconstruction in ischaemic heart failure. A literature review. [Journal Article]Cardiovasc Revasc Med. 2026 Apr 12. [Online ahead of print]CR
- CONCLUSIONS: The Revivent-TC system is associated with LV volume reduction and functional improvements in selected patients, offering a less invasive alternative to surgical ventricular reconstruction. However, the evidence base consists predominantly of small observational studies, and the only controlled trial did not demonstrate significant benefit on hard clinical endpoints. Longer-term randomised data, including a guideline-directed medical therapy comparator arm, are needed before definitive conclusions about efficacy can be drawn.
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- StatPearls: Axial Flaps [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL).BOOK
- An axial pattern flap incorporates an anatomically named vascular pedicle.[1] Due to the direct cutaneous blood supply, a large skin area can be transferred acutely rather than in a delayed fashion that has previously been the gold standard. Historically, random pattern flaps were harvested in a delayed manner to foster better circulation to the flap. There are several advantages when using an ax…
- Sheath Withdrawal May Represent a Mechanically Vulnerable Phase for Septal Perforation During Left Bundle Branch Area Pacing. [Journal Article]J Cardiovasc Electrophysiol. 2026 Apr 19. [Online ahead of print]JC
- CONCLUSIONS: Sheath withdrawal during LBBAP may represent a mechanically vulnerable phase during which geometric constraint and sheath orientation can synergistically amplify axial force transmission to the lead tip. Recognition of this vulnerable phase, together with attention to atrial geometry and sheath orientation during early withdrawal, may help reduce the risk of lead destabilization or overt interventricular septal perforation during LBBAP.
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- Isolated First Septal Perforator Spontaneous Coronary Artery Dissection Causing Acute Myocardial Infarction. [Case Reports]JACC Case Rep. 2026 Apr 16; :107931. [Online ahead of print]JC
- CONCLUSIONS: A limited number of cases of isolated S1 SCAD have been previously reported, predominantly affecting women and all managed conservatively. To our knowledge, this case represents the youngest reported male patient and appears to be the first reported case demonstrating CMR-confirmed transmural septal infarction secondary to type 1 S1 SCAD. Optimal long-term medical therapy remains undefined.SCAD should be considered in patients presenting with chest pain after physical or emotional stress. CMR is a valuable adjunct after angiography in cases of diagnostic uncertainty.
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- Long-term outcomes following nasal button battery foreign body injuries in children: a 10-year retrospective analysis of 45 patients. [Journal Article]Int J Pediatr Otorhinolaryngol. 2026 May; 204:112819.IJ
- CONCLUSIONS: Nasal BBFB injuries are associated with substantial acute and long term morbidity. Substantial variability in post-removal care and low follow-up rates represent critical gaps in management. Persistent symptoms and progressive structural complications were common, highlighting the need for standardized treatment protocols, mandatory follow-up, and prospective research to optimize long-term outcomes.
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- A Three-Layer Composite Graft Technique for Repair of Medium and Large Nasal Septal Perforations. [Journal Article]Laryngoscope Investig Otolaryngol. 2026 Apr; 11(2):e70401.LI
- CONCLUSIONS: The surgical technique utilizing a combination of PDS plate, tragal cartilage, and temporalis fascia appears to be a reliable method for the repair of medium and large septal perforations, with a high success rate and a low risk of complications. Compared to techniques described in the existing literature, this approach offers significant advantages in terms of structural support and mucosal healing.
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- A case of relapsing polychondritis: a diagnostic challenge in recurrent cartilaginous inflammation and hearing loss-A case report. [Journal Article]J Med Case Rep. 2026 Apr 12. [Online ahead of print]JM
- CONCLUSIONS: This case underscores the critical importance of considering relapsing polychondritis in patients with recurrent cartilaginous inflammation and sudden hearing loss. The patient's delayed diagnosis led to permanent hearing impairment, highlighting the necessity for heightened awareness and prompt treatment to mitigate the potential for lasting consequences. Early recognition and management of relapsing polychondritis can significantly improve patient outcomes and quality of life.
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- Unprecedented Complication of Left Bundle Branch Pacing: Ventricular Septal Defect With Mitral Valve Injury. [Case Reports]JACC Case Rep. 2026 Apr 09; :107858. [Online ahead of print]JC
- CONCLUSIONS: This case highlights a unique, previously unreported combination of ventricular septal rupture and valvular injury after LBBP.Although rare, conduction system pacing can result in mechanical complications such as septal injury and mitral chordal entrapment. Monitoring of pacing parameters, including abrupt impedance changes or resistance during lead manipulation, may aid in early recognition of tissue entrapment and prevent structural damage.
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- Pan-Immune-Inflammation Value: Related to Perforation Diameter and Pulmonary Artery Pressure in Ventricular Septal Rupture Patients. [Journal Article]Mediators Inflamm. 2026; 2026(1):e5407966.MI
- CONCLUSIONS: PIV may serve as an adjunct inflammatory marker in VSR patients undergoing transcatheter closure; however, the break point findings are exploratory and the incremental predictive value warrants validation in larger, independent cohorts with better adjudication of infection/systemic inflammation.
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