- External Validation of Published Scoring Systems to Predict Incident Atrial Fibrillation After Cryptogenic Stroke/Embolic Stroke of Undetermined Source. [Journal Article]J Am Heart Assoc. 2026 Jun 23; :e047601. [Online ahead of print]JA
- CONCLUSIONS: C2HEST, Brown ESUS-AF, and AS5F scores reliably predicted AF in patients with CS/ESUS and may help identify low-risk individuals, supporting more targeted use of diagnostic tools and guiding stroke prevention strategies.
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- Association of ischaemic stroke/TIA with subsequent oral anticoagulant adherence in patients with atrial fibrillation: a scoping review. [Journal Article]BMJ Open. 2026 Jun 22; 16(6):e112736.BO
- CONCLUSIONS: Existing evidence shows mixed associations between ischaemic stroke and OAC adherence and causality also remains inconclusive. There are multiple factors that modify this relationship. Further observational studies using causality methods are needed to definitively confirm this relationship.
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- Vascular Eagle syndrome presenting with expanding cervical hematoma and acute ischemic stroke causing impending airway compromise. [Case Reports]Am J Emerg Med. 2026 Jun 17; 109:15-18. [Online ahead of print]AJ
- CONCLUSIONS: This case highlights a rare presentation of vascular Eagle syndrome producing simultaneous hemorrhagic airway compromise and ischemic stroke. Early recognition of airway compromise and prompt multidisciplinary intervention were essential for successful management.
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- Dynamic Angiography Demonstrating Discogenic Bow Hunter Syndrome. [Journal Article]Stroke. 2026 Jul; 57(7):e239-e240.S
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- Idiopathic isolated pulmonary artery aneurysm: a case report. [Case Reports]Eur Heart J Case Rep. 2026 Jun; 10(6):ytag398.EH
- Pulmonary artery aneurysms (PAAs) are rare vascular anomalies, most commonly associated with pulmonary hypertension, congenital heart disease, vasculitis, or infection. Idiopathic PAAs, lacking an identifiable underlying cause, are exceptionally rare and often discovered incidentally. This case illustrates the diagnostic approach and rationale for conservative management of idiopathic PAAs in the…
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- Direct oral anticoagulants versus vitamin K antagonists after left atrial appendage occlusion: a systematic review and meta-analysis. [Systematic Review]BMC Cardiovasc Disord. 2026 Jun 19. [Online ahead of print]BC
- CONCLUSIONS: DOACs may provide comparable thromboembolic protection with a lower risk of major bleeding than VKAs after LAAO. However, most available evidence is derived from non-randomized studies and remains subject to residual confounding, selection bias, and moderate-to-low certainty of evidence. Therefore, the observed benefits of DOACs should be interpreted cautiously. Further large-scale prospective studies and randomized controlled trials are needed to confirm these findings and inform optimal post-LAAO anticoagulation strategies.
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- Interventions for Silent Brain Infarction and Perioperative Neurocognitive Disorders in Cardiovascular Surgery (INSPIRE): study protocol for a multicentre randomised controlled trial. [Randomized Controlled Trial]BMJ Open. 2026 Jun 19; 16(6):e116246.BO
- The incidence of silent brain infarction (SBI) and perioperative neurocognitive disorders (PND) is higher in cardiac surgery. However, standard preventive strategies remain unknown due to limited evidence.
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- Carbamazepine-Induced Paroxysmal Dysarthria and Ataxia in an Elderly Patient: A Case Report and Clinical Considerations. [Case Reports]
- To report a case of carbamazepine-induced neurotoxicity presenting as paroxysmal dysarthria with ataxia, and to highlight clinical risk factors and diagnostic challenges. This case mimicked a transient ischemic attack (TIA), representing a significant diagnostic pitfall. We present the case of a 71-year-old woman who developed acute paroxysmal dysarthria and ataxia after initiating carbamazepine …
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- Diagnostic performance of prehospital large-vessel occlusion detection scales in patients with suspected acute stroke: a retrospective validation study. The Akershus Study of Ischemic Stroke and Thrombolysis. [Journal Article]Eur Stroke J. 2026 Jun 02; 11(6).ES
- CONCLUSIONS: This highlights fundamental limitations of using clinical scales alone to detect LVO in real-world stroke code populations. Registration: ClinicalTrials.gov, https://clinicaltrials.gov/study/NCT05378490, NCT05378490.
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- In-hospital cardiovascular outcomes of COVID-19-associated cytokine storm: a population-level study. [Journal Article]Front Epidemiol. 2026; 6:1836720.FE
- CONCLUSIONS: Within this cohort, advanced CS demonstrated an association with increased mortality and select cardiovascular complications in hospitalized COVID-19 patients; Moreover, certain events, such as arrhythmias and heart failure, showed nuanced patterns, underscoring the complex interplay between hyperinflammation and cardiac pathophysiology.
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- Arterial input function dispersal generated by brain computed tomography perfusion is associated with cerebral small vessel disease in stroke patients. [Journal Article]J Stroke Cerebrovasc Dis. 2026 Jun 18; 35(8):108681. [Online ahead of print]JS
- CONCLUSIONS: Arterial input function dispersal was independently associated with total small vessel disease burden, suggesting it may be a useful risk marker for cumulative microvascular injury in addition to indicating cardiac dysfunction.
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- Cardiovascular Events in Patients With Acute Myeloid Leukemia Treated With Venetoclax: A Multicenter Cohort Study. [Journal Article]JACC Adv. 2026 Jun; 5(6 Pt 2):102821.JA
- CONCLUSIONS: MACE are frequent and occur early in patients with AML treated with HMA-VEN, particularly in patients with diabetes, and are associated with lower survival.
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- Ratio of Left Atrial and Ventricular Volume as New Marker of Atrial Cardiopathy and Stroke Risk. [Journal Article]Stroke. 2026 Jun 18. [Online ahead of print]S
- CONCLUSIONS: We provide evidence that LA:LV ratio is a strong, novel marker of atrial cardiopathy. Hence, LA:LV ratio has the potential to improve the diagnosis of atrial cardiopathy, facilitating the prophylaxis of ischemic stroke and maintaining brain health.
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- Study of Antithrombotic Treatment After Intracerebral Hemorrhage-Antiplatelets: A Randomized Trial. [Journal Article]Stroke. 2026 Jun 18. [Online ahead of print]S
- CONCLUSIONS: There were numerically more recurrent ICHs and fewer ischemic events in patients starting antiplatelet treatment after ICH compared with those avoiding antiplatelet treatment. The slow recruitment might be due to clinicians being certain of the best treatment strategy or patients being too frail to participate. STATICH will contribute to a planned collaborative individual patient-data meta-analysis to resolve this dilemma.
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- Screening for undiagnosed obstructive sleep apnea in patients with acute stroke or TIA. [Journal Article]BMC Neurol. 2026 Jun 17. [Online ahead of print]BN
- CONCLUSIONS: A substantial proportion of patients with ischemic stroke or TIA have a previously unrecognized risk of OSA, while excessive daytime sleepiness is relatively uncommon. STOP-Bang and ESS appear to capture different aspects of sleep-disordered breathing and sleep-related symptoms. STOP-Bang identified a larger proportion of patients at risk of OSA, whereas ESS provided complementary information on subjective daytime sleepiness. Routine screening for OSA symptoms may improve identification of modifiable risk factors relevant for stroke prevention.
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