BackgroundHydrometrocolpos secondary to congenital vaginal atresia is a rare neonatal anomaly, usually diagnosed during puberty, resulting from obstructed uterovaginal secretions under maternal estrogen influence, which rarely leads to urinary tract compression, obstruction and renal dysfunction.Case presentationWe report a preterm 33-week neonatal Asian female delivered by normal vaginal delivery. Antenatal ultrasound revealed bilateral enlarged kidneys, ascites, and polyhydramnios. Postnatally, she developed sepsis, and elevated serum creatinine levels. Abdominal ultrasound and magnetic resonance imaging showed a cystic abdominopelvic mass with enlarged kidneys. Exploratory laparotomy confirmed congenital vaginal atresia. Following surgical intervention, the patient stabilized, with marked improvement in renal function.ConclusionAlthough congenital vaginal atresia is usually diagnosed at puberty, it can present in the neonatal period; early diagnosis and appropriate management are crucial to prevent complications and achieve favorable outcomes.

Ureteral strictures remain a major challenge in reconstructive urology and can arise from iatrogenic injury, chronic inflammation, trauma, congenital anomalies, or radiation. These lesions frequently lead to progressive obstructive uropathy and loss of renal function. Despite advances in endoscopic and surgical techniques, ureteral strictures remain challenging to address, and their remodeling effects on the renal parenchyma remain the subject of ongoing research, underscoring the need for robust preclinical models. This study establishes a reproducible rat model for controlled induction of various degrees of segmental ureteral strictures using wire‑calibrated partial ligation via midline laparotomy. The protocol enables segmental, non‑transecting constriction of the ureter, intended to approximate fibrotic narrowing at a functional and anatomical level while minimizing evident ischemic damage and maintaining macroscopic tissue viability with ureteral continuity. By providing a reliable experimental platform with low inter‑animal and inter-surgeon variability, this approach supports translational research on biomolecular mechanisms, biomaterials, imaging modalities, and reconstructive techniques for ureteral stricture disease.

Background and Objectives: Lower urinary tract symptoms (LUTS) are highly prevalent among aging men and have traditionally been attributed primarily to benign prostatic hyperplasia (BPH) and bladder outlet obstruction (BOO). However, growing evidence suggests that bladder-related mechanisms play a critical and often underrecognized role. This review aims to summarize current evidence on the contribution of the aging bladder to LUTS pathophysiology and to explore the therapeutic implications in men with BPH. Materials and Methods: A comprehensive literature search was conducted in PubMed/MEDLINE, Scopus, and Web of Science for studies published between January 2010 and April 2025. Search terms included combinations of "aging bladder", "detrusor dysfunction", "LUTS", "BPH", "bladder outlet obstruction", "ischemia", "overactive bladder", and "detrusor underactivity". Eligible studies included narrative reviews, systematic reviews, meta-analyses, clinical studies, and translational research addressing bladder aging and its clinical implications. A narrative synthesis approach was used due to heterogeneity in study design and outcomes. Results: A total of 43 studies were included in the qualitative synthesis. The evidence indicates that LUTS in older men result from multifactorial processes involving not only prostatic enlargement but also bladder dysfunction. Aging-associated changes include detrusor remodeling, impaired compliance, neural alterations, and vascular insufficiency, particularly chronic ischemia and oxidative stress. These mechanisms contribute to both detrusor overactivity and underactivity, providing a unifying framework for storage and voiding symptoms. Importantly, the severity of LUTS does not consistently correlate with prostate size or degree of obstruction. Conclusions: LUTS in aging men should be considered a complex condition involving both bladder and outlet factors. A bladder-centered perspective may improve patient stratification and therapeutic outcomes. Integrating bladder-targeted therapies with conventional BPH management supports a more personalized and effective approach to care.

Zinner syndrome is a rare congenital anomaly of the male genitourinary tract, characterized by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. Owing to its low prevalence and nonspecific clinical presentation, diagnosis is often delayed or incidental, with imaging playing a central role in detection and characterization. This study presents a narrative review with an illustrative case report, aiming to summarize the imaging features of Zinner syndrome, outline the main radiologic differential diagnoses of seminal vesicle cysts, and highlight common diagnostic pitfalls, with emphasis on cross-sectional imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI). The narrative review of the literature highlights that CT and MRI are essential for accurate anatomical localization, characterization of cystic content, and identification of associated genitourinary anomalies. MRI, in particular, provides superior soft-tissue contrast and is considered the reference modality for diagnosis and differential evaluation of male pelvic cystic lesions. Key differential diagnoses include Müllerian duct cysts, prostatic utricle cysts, and ejaculatory duct cysts. As an illustrative example, we report the case of a young adult male presenting with pelvic discomfort, infertility, and mild lower urinary tract symptoms. Imaging findings, including ultrasound and cross-sectional studies, demonstrated a seminal vesicle cyst associated with ipsilateral renal agenesis, consistent with Zinner syndrome. Zinner syndrome should be considered in the evaluation of male pelvic cystic lesions, particularly in the presence of unilateral renal agenesis. Awareness of its characteristic imaging features is essential for accurate diagnosis and appropriate management, with MRI playing a pivotal role in confirming the diagnosis and distinguishing it from other pelvic cystic entities.