Obesity is the most common health care problem in women of reproductive age,[1] with 36.5% of American women 20 to 39 years of age classified as obese (BMI ≥30.0 kg/m²) by the Centers of Disease Control and Prevention’s National Health and Nutrition Examination Survey.[2] Obesity poses risks to the pregnant woman and her fetus from conception through postpartum. OB/GYN hospitalists can lead initiatives that optimize care for women with obesity in the Maternity unit. Opportunities include developing protocols and order sets to provide appropriate dosing of VTE prophylaxis and antibiotics, ensuring that all necessary equipment is available on labor and delivery for managing patients with obesity, and ensuring that women with sleep apnea are managed appropriately during labor and postpartum.