Perioperative Anticoagulation and Antithrombotic Management

Perioperative Anticoagulation and Antithrombotic Management is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

  • Patients on chronic anticoagulation for AF, VTE, or mechanical heart valves often need to undergo procedures that pose risk of bleeding.
  • The indication for anticoagulation and risk of interruption must be weighed against the risk of bleeding of the procedure (including possible neuraxial anesthesia).
  • Until better research is available, decisions regarding perioperative anticoagulation will have to be made with the help of guidelines with relatively weak strength of evidence.1

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General Principles

  • Patients on chronic anticoagulation for AF, VTE, or mechanical heart valves often need to undergo procedures that pose risk of bleeding.
  • The indication for anticoagulation and risk of interruption must be weighed against the risk of bleeding of the procedure (including possible neuraxial anesthesia).
  • Until better research is available, decisions regarding perioperative anticoagulation will have to be made with the help of guidelines with relatively weak strength of evidence.1

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