Alcoholic Liver Disease
Alcoholic Liver Disease is a topic covered in the Washington Manual of Medical Therapeutics.
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General Principles
- Alcohol use disorder is a significant medical and socioeconomic problem.
- Patients may underestimate or minimize their reported alcohol abuse.
- According to the 2015 National Survey on Drug Use and Health, 15.1 million US adults age 18 and older (6.2% of this age group) had alcohol use disorder.
- The spectrum of alcoholic liver disease includes fatty liver, alcoholic steatohepatitis, severe alcoholic hepatitis, and cirrhosis. Fatty liver is the most common and occurs in up to 90% of alcoholics.
- Of all excessive alcohol users, between 10% and 20% will develop cirrhosis and 35% will develop alcoholic hepatitis. More than half of the latter will progress to cirrhosis.
- Alcoholic cirrhosis is a common cause of ESLD and HCC.
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Citation
Williams, Dominique, et al., editors. "Alcoholic Liver Disease." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602025/all/Alcoholic_Liver_Disease.
Alcoholic Liver Disease. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602025/all/Alcoholic_Liver_Disease. Accessed December 10, 2019.
Alcoholic Liver Disease. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602025/all/Alcoholic_Liver_Disease
Alcoholic Liver Disease [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 December 10]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602025/all/Alcoholic_Liver_Disease.
* Article titles in AMA citation format should be in sentence-case
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T1 - Alcoholic Liver Disease
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ED - Ramgopal,Rajeev,
ED - Gdowski,Mark,
ED - Dretler,Alexandra,
ED - Bhat,Pavat,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602025/all/Alcoholic_Liver_Disease
PB - Wolters Kluwer Health
ET - 35
DB - Washington Manual
DP - Unbound Medicine
ER -